Pharm Unit 1 CAM Flashcards
OTC drugs include the following (3):
- Herbals. 2. Vitamins. 3. Nutritional Supplements.
The major categories for self-care include (7)
- Respiratory. 2. Feminine. 3. Pain. 4. Digestive. 5. Eye/ear/mouth. 6. Skin. 7. General well-being.
These OTC meds interefere with absorption of tetracyclines, fluoroquinolones, biphosphanates & impair absorption of iron.
Antacids.
This OTC meds alkalinize stomachic pH, reduce absorption of keoconazole, and increase renal clearance of Lithium and aspirin.
Sodium bicarbonate.
These OTC meds interefere with antihypertensive effectiveness of beta-blockers, may also increase serum Lithium levels and interfere with the cardio-protection of low-dose aspirin.
Ibuprofen & Naproxen.
When botanicals are recognized for medicinal effect.
Phytomedicine/Herbal medicine.
OTC=
Over the counter.
An botanical used in some Latino cultures to induce abortion. A therapeutic dose can also cause renal failure.
Anise tea.
OTC meds are sold as dietary supplements (not drugs) in the US under this act:
1994 Dietary Supplement Health and Education Act.
When taking OTC/herbal meds, the most common drug interaction concern is the potentiation of:
Coumadin (Anticoagulant effect).
Common probiotics:
Lactobacillus and Saccharomyces.
This herbal induces paralysis via blockade of Acetylcholine release.
Botulinum Toxin A (botox).
A term used for excessive sweating.
Hyperhidrosis.
This analgesic is derived from white willow bark and meadowsweet.
Aspirin.
This opiate is derived from poppy.
Opium.
This herb yielded the original hormonal components of the first tested oral contraceptives.
Dioscorea villosa (Mexican Yam).
Two herbs used in Chemotherapy treatment in traditional medicine:
- Vinca (periwinkle); vincristine and vinblastine. 2. Yew Tree (taxol).
This herb is used as a cardiac tonic for heart failure and cardiac arrhythmias.
Foxglove (Digitalis).
This is a naturally derived plant that depletes substance P from skin nerve endings to reduce pain and inflammation.
Chili (Cayenne) peppers–>Capsaicin.
This is a commonly used herbal that has serious clinical implications. The active ingredient is hypericin which is used as an antidepressent. However, there is drug-drug concern of serotonin syndrome or induction of CYP3A4 biotransformation pathway.
St. John’s Wort.
Two juices that may affect medications:
- Grapefruit juice. 2. Pomegranate Juice.
These crucial enzymes are found in both the Intestine and the Liver.
CYP enzymes.
4 types of Food Reactions (allergies):
- Food Hypersensitivity and Anaphalaxis (reaction to eggs). 2. Food Intolerance (gluten sensitivity). 3. Food Toxicity (poisoning from microbes). 4. Food Idiosyncrasy (MSG syndrome).
An FDA act requiring food allergen labeling:
Food Allergen Labeling and Consumer Protection Act.
Rapid edema (swelling) in deep layers of the skin.
Angioedema.
High-pitched, wheezing sound.
Stidor.
If you are allergic to one thing, there is a good chance you will be allergic to another related chemical.
Cross-reactivity.
3 common food additives that can cause an allergic response:
- Sulfites. 2. MSG (Monosodium Glutamate). 3. Food Dyes.