Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

STEP 1 (5) > Pharm- Toxicities and Side Effects > Flashcards

Pharm- Toxicities and Side Effects Flashcards

1
Q

What is the antidote for Acetaminophin OD?

A

N-acetylcysteine (replenishes glutathione)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the antidote for AChE inhibitor, organophosphates OD?

A

Atropine > pralidoxime

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the antidote for Amephetamines (basic) OD?

A

NH4Cl to acidify urine to trap it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the antidote for Antimuscarinic, anticholinergic OD?

A

Physostigmine salicylate, control hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the antidote for Benzo OD?

A

Flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the antidote for BB OD?

A

Glucagon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the antidote for copper, arsenic, gold OD?

A

Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the antidote for Cyanide OD?

A

Nitrate + thiosulfate, hydroxocobalamin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the antidote for heparin OD?

A

Protamine sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the antidote for iron OD?

A

Deferoxamine or Deferasirox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the antidote for Lead OD?

A

EDTA, dimercaprol, succimer, penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the antidote for Mercury OD?

A

Dimercaprol (BAL), succimer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the antidote for Methemoglobin OD?

A

Methylene blue, vitC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the antidote for Opiods OD?

A

Naloxone, naltrexone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the antidote for Salicyclate OD?

A

NaHCO3 (alkalinize urine), dialysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the antidote for tpA, streptokinase, urokinase OD?

A

Aminocaproic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the antidote for Warfarin OD?

A

vit K or fresh frozen plasma (faster)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What drugs can produce hot flashes as an AE?

A

Tamoxifen and Clomiphene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What drugs can produce hyperglycemia as an AE?

A

Tacrolimus, protease inhibitors, niacin, HCTZ, steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What drugs can produce hypothyroidism as an AE?

A

Lithium, amiodarone, sulfonamides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What drugs can produce acute cholestatic hepatitis, jaundice as an AE?

A

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What drugs can produce diarrhea as an AE?

A

Metofrmin, erythromycin, colchicine, orlistatm and acarbose

Might Excite Colon on Accident

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What drugs can produce focal to massive hepatic necrosis as an AE?

A

Halothane, Amanita phalloides (death cap mushrooms), Valproic acid acetaminophen

Liver ā€œHAVAcā€

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What drugs can produce hepatitis as an AE?

A

Rifampin, isoniazid, pyrazinamide, statins, and fibrates

25
What drugs can produce pancreatitis as an AE?
Didanosine, steroids, alcohol, valproic acid, azathioprine, diuretics (furosemide, HCTZ)
26
What drugs can produce pseudomembranous colitis as an AE?
Clinamycine, ampicillin, cephalosporins
27
What drugs can produce agrnaulocytosis as an AE?
ganciclovir, clozapine, carbamazepine, colchicine, methimazole, propthiouracil
28
What drugs can produce asplastic anemia as an AE?
Carbamazepine, methimazole, NSAIDs, Benzene, chloramphenicol, and propylthiouracil
29
What drugs can produce a driect coombs positive test as an AE?
Methyldopa and pencillin
30
What drugs can produce grey baby syndrome as an AE?
Chloramphenicol
31
What drugs can produce hemolysis in G6PD deficiency as an AE?
Isoniazid, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin
32
What drugs can produce megaloblastic anemia as an AE?
Phenyotin, Methotrexate, sulfa drugs
33
What drugs can produce thrombocytopenia as an AE?
heparin
34
What drugs can produce thrombotic issues as an AE?
OCPs, and hormone replacement therapy
35
What drugs can produce fat redistribution as an AE?
Protease inhbitors and steroids Fat PIG
36
What drugs can produce gingival hyperplasia as an AE?
Phenytoin, CCBs, Cyclosporine
37
What drugs can produce hyperuricemia as an AE?
Pyrazinamide, Thiazides, Furosemide, Niacin, and Cyclosporine Painful Tophi and Feet Need Care
38
What drugs can produce myopathy as an AE?
Fibrates, niacin, colchicine, hydroxychloroquine interferon-a perincillamine statins steroids
39
What drugs can produce osteoporosis as an AE?
Steroids and heparin
40
What drugs can produce photosensitivity as an AE?
Sulfonamides, amiodarone, tetracyclines, and 5-FU SAT For Photo
41
What drugs can produce SJS/TEN as an AE?
Anti-epileptic durgs (esp. lamitrigine), allopurinol, sulfa drugs, penicillin
42
What drugs can produce a SLE like syndrome as an AE?
Sulfa drug, hydralazine, isoniazid, procainamide, phenyotin, etanercept
43
What drugs can produce tendon rupture as an AE?
Fluroquinolones
44
What drugs can produce cinchonism (Cinchonism or quinism is a pathological condition caused by an overdose of quinine or quinidine) as an AE?
Quinidine or quinine
45
What drugs can produce Parkinson-like syndrome as an AE?
Antipsychoics, Reserpine, Metoclopramide
46
What drugs can produce seizures as an AE?
Isoniazid, Bupropion (esp. with eating disorder), Imipenem, Enflurane
47
What drugs can produce tardive dyskinesia as an AE?
Antipsychotcs, metoclopramide
48
What drugs can produce diabetes inspidius as an AE?
Lithium or demeclocycline
49
What drugs can produce Fanconi syndrome as an AE?
Expired tetracycline
50
What drugs can produce hemorrhagic cystitis as an AE?
Cyclophsophamide or ifosfamide (prevent with mesna)
51
What drugs can produce interstitial nephritis as an AE?
Methicillin, NSAIDS, and furosemide
52
What drugs can produce SIADH as an AE?
Carbamazepine, Cyclophosphamide, SSRIs
53
What drugs can produce dry cough as an AE?
ACEIs
54
What drugs can produce pulmonary fibrosis as an AE?
Bleomycin, Amiodarone, Busulfan, Methotrexate
55
What are the CYP inducers?
Chronic alcohol use St. Johns Wort Phenytoin, Phenobarbital, Carbamazepinr Nevirapine Griseofulvin
56
What are the CYP inhbitors?
Acute alcohol use Ritonavir Amiodarone cimetidine ketoconazole Sulfonamides Grapefruit juice Quinidine Macroplides except azithromycin
57
What are the sulfa drugs?
Probenecid Furosemide, Thiazides Acetazolamide Celecoxib Sulfonamide ABX Sulfasalazine Sulonylureas
58
pts with sulfa allergies may present with:
Fever, UTI, SJS, hemolytic anemia, thrombocytopenia, agranulocytosis, and urticaria

STEP 1 (5) (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions