Autoantibodies Flashcards

1
Q

What disease carries Anti-ACh Abs?

A

Myasthenia gravis

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2
Q

What disease carries Anti-basement Abs?

A

Goodpasture syndrome

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3
Q

What disease(s) carries Anti-cardiolipin Abs?

A

SLE and Antiphospholipid syndrome

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4
Q

What disease(s) carries Anti-centromere Abs?

A

Limited scleroderma

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5
Q

What disease(s) carries Anti-desmosome Abs?

A

Pemphigus vulgaris

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6
Q

What disease(s) carries Anti-glutamic acid decarboxylase (GAD-65) Abs?

A

Type I Diabetes Mellitus

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7
Q

What disease(s) carries Anti-chemidesmosome Abs?

A

Bullous pemphigoid

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8
Q

What disease(s) carries Anti-histone Abs?

A

drug induced lupus

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9
Q

What disease(s) carries Anti-Jo-1, anti-SRP, and anti-Mi2 Abs?

A

Polymyositis or dermatomyositis

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10
Q

What disease(s) carries Anti-thyroglobulin Abs?

A

Hashimoto thyroiditis

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11
Q

What disease(s) carries Anti-mitochondrial Abs?

A

Primary billiary cirrhosis

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12
Q

What disease(s) carries Anti-Scl 70 (anti-DNA topoisomerase I) Abs?

A

Scleroderma (diffuse)

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13
Q

What disease(s) carries Anti-smooth muscle Abs?

A

Autoimmune hepatitis

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14
Q

What disease(s) carries Anti-SSA/SSB Abs?

A

Sjogren syndrome

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15
Q

What disease(s) carries Anti-TSH receptor Abs?

A

Graves disease

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16
Q

What disease(s) carries Anti-U1 RNP (ribnucleoprotein) Abs?

A

Mixed CT disease

17
Q

What disease(s) carries Anti-endomysial, IgA anti-tissue transglutaminase Abs?

A

Celiac disease

18
Q

What disease(s) carries MPO-ANCA/p-ANCA Abs?

A

Microscopic polynagiiitis, esoinophilic granulomatosis with polyangiitis (Churg-Strauss)

19
Q

What disease(s) carries PR3-ANCA/c-ANCA Abs?

A

Wegener (granulomatosis with polyangiitis)