pharm test 2 indications Flashcards by Adriana Blakely

DM type 1

long acting basal with rapid- acting bolus, Pramlintide(symlin)

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DM type 2

secretagogues sulfonylureas(mild to moderate), repaglinide, nateglinide, metformin(DOC), Rosiglitazone(Avandia) and pioglitazone(actos), Sitagliptin(Januvia) and Saxagliptin (onglyza), Acarbose(precise) and miglitol (glyset), Colesevelam (WelChol), Exenatide (Byetta), insulin, Pramlintide(symlin)

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Hypothyroidism

**Levothyroxine(synthroid, levothroid, levoxyl, unithroid)(DOC), liotrix(Euthroid, Thyrolar)

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Myxedema

Liothyronine Sodium (Cytomel, Triostat)

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Myxedema coma

IV bolus Levothyroxine

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Short term suppression of TSH

Liothyronine Sodium (Cytomel, Triostat)

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Hypothyroidism in pregnancy

levothyroxine

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Graves

Radioiodine(DOC)

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Toxic autonomous nodules

Radioiodine

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Toxic multinodulor goiter

radioiodine

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Graves during pregnancy

PTU(DOC)

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Hyperthyroidism

MMI(DOC), PTU

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Thyrotoxic crisis

MMI(DOC), PTU, lithium carbonate

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Preparation for thyroidectomy

MMI(DOC), PTU, KI

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Thyroid storm

corticosteroids

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Thyroiditis

corticosteroids

Iodine induced hyperthyroidism

thioamides and BB

Iodine induced hypothyroidism

levothyroxine

Lithium

levothyroxine

Cushings

Metyrapone(metopirone), Aminoglutethimide(cytadren)

Adrenal adenoma

ketoconazole(Nizoral)

Adrenal carcinoma

Mitotane(lysodren)

Hyperaldosteronism

spironolactone (DOC), eplerenone, amiloride

Hypoaldosteronism

hydrocortisone, prednisone

Addison

Fludrocortisone (Florinef)

Adrenal crisis

Hydrocortisone, IV fluids D5W, BP support, Fludrocortisone(like aldosterone) to decrease potassium levels

Acromegaly

octreotide(1st line), Bromocriptine and Ergot alkaloid, Pegvisomant

GHD short stature

Genotropin(1st line)

Short stature due to primary IGF-1 deficiency

Mescasermin

Hyperprolactinemia

Bromocriptine, Cabergoline(1st line)

Ketoacidosis

rehydrate + normalize serum glucose(NS @ 1L/hr) + (regular insulin @ 0.1-0.2 unit/kg/hr by continuous infusion)