Pharm quiz 1 - Antihypertensives/Diuretics Flashcards
What type of medication is Spironolactone (Aldactone)
K sparing diuretic, Aldosterone receptor antagonist
What type of medication is Furosemide (Lasix)
Antihypertensive, loop diuretic
What type of medication is Hydrochlorothiazide?
Antihypertensive, thiazide diuretic
What type of medication is Metoprolol?
Beta blocker, antihypertensive
What type of medication is Amlodipine (Norvasc)
Antihypertensive, Ca channel blocker
What type of medication is Diltiazem (Cardizem)
Antihypertensive, Ca channel blocker
What type of medication is Lisinopril?
Antihypertensive, angiotensin converting ACE inhibitor
What type of medication is Losartan?
Antihypertensive, angiotensin II receptor blocker
Spironolactone MOA
antagonizes aldosterone in the distal tubules, increasing sodium and water excretion
Furosemide MOA
Inhibits sodium and chloride reabsorption at the proximal and distal tubules and the ascending loop of Henle.
Hydrochlorothiazide MOA
Hydrochlorothiazide inhibits sodium reabsorption in the distal tubules, causing increased excretion of sodium, water, and chloride as well as potassium and hydrogen ions.
Metoprolol MOA
A selective beta blocker that selectively blocks beta1 receptors; decreases cardiac output, peripheral resistance, and cardiac oxygen consumption; and depresses renin secretion.
Amlodipine MOA
Stops calcium from entering the cells of the heart and blood vessels. This relaxes the blood vessels and lowers blood pressure, increasing supply of blood and oxygen to the heart while reducing its workload.
Diltiazem MOA
Inhibits calcium ion influx across cardiac and smooth-muscle cells, decreasing myocardial contractility and oxygen demand. Drug also dilates coronary arteries and arterioles.
Lisinopril MOA
Lisinopril inhibits ACE, leading to decreased angiotensin II production, decreased aldosterone secretion, and increased potassium level.
