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Emma Micro > Pharm Nuggets > Flashcards

Pharm Nuggets Flashcards

1
Q

penicillin resistant to b-lactamase degradation

A

antistaphylococcal penicillins

  • oxacillin
  • nafcillin
  • dicloxacillin
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2
Q

resistant to cleavage by most b-lactamases

A

carbapenems

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3
Q

narrow spectrum b-lactam gram - only

A

aztronam

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4
Q

generally, as cephalosporin generation increases, which coverages inc/dec?

A

gram - increases, gram + decreases

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5
Q

cephalosporin with inc anaerobic coverage

A

2nd gen

  • cefuroxime
  • cefoxitine
  • cefotetan
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6
Q

cephalosporin with good CSF penetration

A

3rd gen

  • ceftriaxone
  • cefotaxime
  • ceftazidme
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7
Q

cephalosporin that binds PBP2a

A

5th gen

-ceftaroline

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8
Q

red man syndrome

A

vancomycin

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9
Q

skel m. toxicity

A

daptomycin

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10
Q

antacids can bind up

A

quinolones

tetracyclines

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11
Q

aminoglycosides have synergistic effects when added to

A

B-lactams

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12
Q

P450 inhib

A

macrolides

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13
Q

mainstay tx of tick-borne illnesses

A

tetracylines

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14
Q

esophageal ulceration

A

tetracyclines

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15
Q

particularly high rates of C. diff with use of

A

clindamycin

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16
Q

serotonin syndrome

A

linezolid

17
Q

kernicterus

A

sulfonamides

18
Q

all of the protein synthesis inhibitors are bacterio___ while aminoglycosides are bacterio____

A

all protein synth inhibitors –> bacteriostatic (block prod of proteins)

aminoglycosides –> bactericidal

19
Q

big guns against MRSA

A

vancomycin
daptomycin
linezolid

20
Q

take a van to the metro when treating

A

C. diff

21
Q

only b-lactam against MRSA

A

ceftaroline (5th gen cephalosporin)

22
Q

which beta-lactam lowers the seizure threshold?

A

imipenem

23
Q

very broad b-lactam can cover pseudomonas

A

piperacillin

24
Q

respiratory quinolones

A

levofloxacin

moxifloxacin

25
Q

gram - (Pseudomonas)

A
  • ceftazidime (3rd)
  • cefepime (4th)
  • aminoglycosides
  • ciprofloxacin
  • aztreonam
  • imipenem
26
Q

gram + (MRSA)

A
  • vancomycin
  • linezolid
  • daptomycin
  • ceftaroline
  • doxycycline
  • SMX-TMR
27
Q

organisms that cause atypical pneumonia can be covered with which abx

A

fluoroquinolone (moxifloxacin)

macrolides

28
Q

Common bacterial causes of community acquired pneumonia

A

Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis

29
Q

organisms causing atypical pneumonia

A

Legionella
Mycoplasma
Chlamydia

30
Q

of all quinolones, which has most effects on gram -

A

ciprofloxacin

including pseudomonas

31
Q

Beta-lactams are not very active against ______ organisms - they require activiely replicating organisms and those that have a cell wall.

A

intracellular

32
Q

rarely used

A

Chloramphenicol

33
Q

protein synthesis inhibitor only active against gram positive organisms?

A

linezolid

Emma Micro (12 decks)

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