Pharm- Insulin Flashcards

1
Q

Rapidly acting- Names

A
  • Lispro (Humalog
  • Aspart (Novolog)
  • Glulisine (Apidra)
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2
Q

Rapidly acting- Indications

A
  • Rapid blood glucose lowering
  • Mimic prandial release of insulin
  • Lower risk of hypoglycemia
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3
Q

Rapidly acting- Peak & duration

A
  • 15 - 30 min peak

- Lasts 2 hrs

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4
Q

Short acting- Names

A

Humalin R, novalin R

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5
Q

Intermediate acting- Names

A

NPH, Humalin N, Novalin N

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6
Q

Intermediate acting- Peak & duration

A

Peak: 5-6 hrs

Duration- Up to 18 hrs

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7
Q

Intermediate acting- Indications

A

Basal control, should be used with meal time control

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8
Q

Long acting- Names

A

Glargine, detemir

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9
Q

Long acting- Indications

A

Basal control

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10
Q

Insulins- SE

A
  • Hypoglycemia
  • Blurry vision
  • Skin reaction- lipohypertrophy
  • Hypersen. rxn
  • Wt gain
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11
Q

Sliding scale approach

A
  • Change dose depending on postprandial blood sugar
  • Basal insulin + short acting to cover meals
  • High sugar = higer insulin dose
  • Increased by 2 units based increase in glucose by 50
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12
Q

Glycemic control in DM

A
  • Fasting: 80-130
  • Post meal: <8%
  • Control BP
  • Goal to prevent frequent hypoglycemia
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13
Q

Type 2- Initial insulin

A
  • Late in dx, due to beta cell exhaustion
  • Long acting to start
  • Add pre-prandial if BG not controlled
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14
Q

Type 1- Initial inulin

A
  • Initial therapy

- Basal & bolus required

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