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Quarter 3 > Pharm II- Exam 1 Simple Review > Flashcards

Pharm II- Exam 1 Simple Review Flashcards

1
Q

Alpha blockers

A

Phentolamine
Phenoxybenzamine
Prazosin
Tamsulosin

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2
Q

Beta blockers

A 
Propranolol
Timolol
Metoprolol
Betaxolol
Nebivolol
Esmolol
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3
Q

A1 and Beta (all) blockers

A

Labetolol

Carvedilol

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4
Q

Phentolamine (Regitine)

A 
decrease BP (Rarely used for HTN crisis)
contra: CAD
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5
Q

Phenoxybenzamine

A

IRREVERSIBLE

DOC to prevent HTN in Pheochromo b4 surgery

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6
Q

Prazosin (Minipress)

A

BPH and HTN

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7
Q

Tamsulosin (Flomax)

A

BPH only

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8
Q

Propranolol

A

all the heart stuff and inc exercise tolerance
non specific beta- blocker

Contra:
Acute HT, Asthma, AV block, Bradycardia, Cardiogenic shock, Pheochromocytoma

Caution: P450 intxns

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9
Q

Metoprolol

A

just like Propranolol except less side effects bc blocks B1 only

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10
Q

Timolol (Timoptic)

A

Glaucoma

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11
Q

Betaxolol (Betoptic)

A

Glaucoma (2nd choice, B1 selective)

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12
Q

Nebivolol

A

most selective beta blocker but expensive so not used often

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13
Q

Esmolol

A

for critically ill, when quick effect is needed i.e. Arrhythmia

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14
Q

Labetolol

Carvedilol

A

A1 and B (all) blocker
Vasodilation w/o Reflex Tachy
Contra: Asthma

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15
Q

NE

A

rarely used in Hypotensive crisis

A and B1&raquo_space;» B2

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16
Q

Epinephrine (Adrenilin)

A

Beta > Alpha

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17
Q

Epinephrine (Adrenaline) use

A

Anaphylactic shock
Glaucoma
Cardiac arrest
Decrease diffusion of injected drugs

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18
Q

Isoproterenol

A

potent Beta only agonist

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19
Q

Isproterenol use

A

cardiac arrest, heart block, activates the SA and AV node

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20
Q

Phenylephrine (Neofrin)

A

decongest, dilate eyes, hypotensive emergency

Rebound effect

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21
Q

Phenylephrine (Neofrin)

A

Rebound effect

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22
Q

Oxymetazoline (Afrin)

A

decrease redness in eyes

decrease nasal congestion

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23
Q

Clonidine & Methyldopa

A

decrease HTN
decrease cravings
decrease hot flashes
dry up secretions pre-anesthesia

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24
Q

Tizanidine

A

reduce spasticity in neuro conditions

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25
Q

Dobutamine

A

B1

Stress tests, increase contractility and cardiac output

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26
Q

Albuterol

A

B2

Asthma

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27
Q

Mirabegron

A

B3

overactive bladder

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28
Q

Dopamine

A

short term for refractory HF

do NOT give with MAOi

29
Q

Fenoldopam

A

Dopamine receptor

Emergency HTN

30
Q

Amphetamine (Adderall)
Methylphenidate (Ritalin)
Methamphetamine (Desoxyn)

A

Increase release of NE

Increase alertness and decrease appetite and tiredness

31
Q

Cocaine

A

inhibit re-uptake of NE

local anesthetic and powerful vasoconstrictor

32
Q

Tyramine

A

increase Catecholamine release

33
Q

do NOT mix MAOis with

A

Dopamine or

Tyramine

34
Q

Direct Acting Cholinergic (M or N) Agonist

A

Bethanechol
Pilocarpine
Nicotine
Varenicline

35
Q

Bethanechol-M

A

Urinary retention

Increase GI motility

36
Q

Pilocarpine-M

A

Tx Xerostomia

Last choice for Glaucoma

37
Q

Nicotine

A

activates Symp and Parasymp

38
Q

Varenicline (Chantix)

A

stop smoking

39
Q

ACE-I (6)

A 
Neostigmine/Pyridostigmine
Physostigmine
Edrophonium
Donepezil
Organophosphates
40
Q

Neostigmine/Pyridostigmine

A

Myasthenia Gravis

Reverse bock post surgery

41
Q

Physostigmine

A

nuttin’, rare for Atropine poisoning

42
Q

Edrophonium

A

tester for Myasthenia tx

43
Q

Donepezil

A

Alzheimer’s tx!!

44
Q

Organophosphates

A

SLUDE poisoning

Tx with Atropine and 2-PAm

45
Q

Overall effects of ACE-Inhibitors

A 
Increase alertness
Miosis
Salivation
Secretion
Bronchoconstriction
Bradycardia
46
Q

Anticholinergics- Cholinergic (M and N) Antagonist

9

A 
Atropine
Scopolamine
Tropicamide
Ipratropium/Atrovent
Tolterodine/Feso/Darif/Solif
Oxybutynin
Dicyclomine/Bentyl
Botox
Succinychol
47
Q

Atropine

A 
Reverse bradycardia
Heart block
Post MI
Tx diarrhea
Muscarine poisoning
48
Q

Scopolamine

A

Motion sickness

49
Q

Tropicamide

A

Eye exam

dilate eyes

50
Q

Ipratroprium (Atrovent)

A

COPD

sometimes Asthma

51
Q

Tolterodine/Fesoterodine/Darifenacin/Solifenacin

A

Overactive bladder

M3 selective

52
Q

Oxybutynin

A

Bladder spasms post surgery or in neurogenic dz

53
Q

Dicyclomine (Bentyl)

A

Diarrhea predominant IBS

54
Q

Botox

A

blocks Ach release
Urinary incontinence
Migraine
Wrinkles

55
Q

Succinylcholine

A

Depolarizing blocker

Tracheotomy and Intubation

56
Q

Propranolol (b1 b2) and Metoprolol (b1) CONTRA

A 
Acute HF
Asthma
AV block
Bradycardia
Cardiogenic shock
Pheochromocytoma

strong caution in Diabetics

57
Q

Prazosin (a1 block) CONTRA

A

Viagra (ED drugs)

Nitrates

58
Q

Phentolamine (nonspec a block)
used for emergency HTN
CONTRA

59
Q

Epinephrine CONTRA

A

ppl also taking b-blockers

can cause severe HTN

60
Q

Phentylephrine (Neofrin) (a1 agonist)

CONTRA

A

ppl w/BPH and HTN

61
Q

Pseudoephedrine (Sudafed) (a1 agonist)

CONTRA

A

caution w/BPH and HTN

62
Q

Oxymetazoline (Afrin)

CONTRA

A

caution w/closed angle glaucoma and HTN

63
Q

Clonidine and Methyldopa CONTRA

A

Not rec as Monotherapy

64
Q

Clonidine advice

A

Avoid sudden withdrawal–> HTN crisis

Avoid getting patch hot –> Hypotension

65
Q

Dopamine (used for short term refractory HF) CONTRA

A

MAO-Inhibitors

66
Q

Tyramine CONTRA

A

MAO-Inhibitors –> severe HTN crisis

67
Q

Muscarinic Agonists CONTRA

A

Asthma/COPD
Peptic ulcers
Bowel obstruction
Coronary insuff/heart dz

68
Q

Muscarinic Antagonists CONTRA

A

Acute angle glaucoma

BPH

69
Q

Succinylcholine CONTRA

A

Hx malignant hyperthermia
Extensive soft tissue damage
Burns

Caution: teens and children

Quarter 3 (17 decks)

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