Pharm Final Exam Flashcards
1
Q
What drug is used for heroin withdrawal that is only given at approved centers?
A
Methadone
2
Q
What drug is used for alcohol use disorder and for maintenance of sobriety?
A
Disulfiram
3
Q
What drug produces unpleasant hangover-like symptoms when alcohol is consumed?
A
Disulfiram
4
Q
What are some nursing interventions for magnesium sulfate?
A
Monitor cardiac and neuromuscular status, labs, and VS
5
Q
What is used for magnesium toxicity?
A
Calcium gluconate
6
Q
What is ferrous sulfate?
A
Iron preparation; RBC development and O2 transport
7
Q
What should be used to prevent teeth staining when taking ferrous sulfate?
A
Straw
8
Q
Ferrous sulfate should be taken
A
On an empty stomach
But if GI distress, with food but prolonged treatment due to poor absorption
9
Q
What happens if Beta 1 is blocked?
A
Decreased BP and HR
10
Q
What happens if Beta 2 is blocked?
A
Bronchoconstriction
11
Q
What is Beta Blocker used for?
A
HTN, reflex tachycardia
12
Q
What is the main nursing consideration for Beta Blockers?
A
Change position slowly (orthostatic hypotension)
13
Q
How do you recognize Benzodiazepines?
A
~lam, ~pam
14
Q
What is Benzodiazepines used for?
A
General anxiety disorder, panic disorder, trauma/stressor related disorder, hyperarousal, seizure, insomnia, muscle spasm, ETOH withdrawal
15
Q
What do you use for Benzodiazepine toxcitity?
A
Gastric lavage, activated charcoal, saline cathartics, flumazenil, crash cart
16
Q
What should you teach patient on Benzodiazepine?
A
S/S CNS/respiratory depression, avoid activities that requires alertness, avoid other CNS depressants, report paradoxical response, s/s withdrawal, taper med off when dc, limit continuous use, avoid grapejuice
17
Q
What should you avoid with all of the psych meds?
A
Grapefruit juice
18
Q
What are some s/e & a/e of Benzodiazepines?
A
Hangover feeling, REM rebound, CNS/respiratory depression, anterograde amnesia, toxicity, paradoxical response, physical dependence, tolerance, withdrawal effects, hypersensitivity
19
Q
Benzodiazepines causes
A
Reduced anxiety & sedation
20
Q
What are some drugs for non-benzodiazepines?
A
Zolpidem, Zaleplon, Eszopiclone
21
Q
What do you use non-benzodiazepines for?
A
Short-term insomnia management
22
Q
What are Hydantoins for?
A
Antiseizure
23
Q
What drugs are in Hydantoins?
A
Phenytoin, Ethotoin, Fosphenytoin
24
Q
What are some a/e of Hydantoins?
A
Cardiac collapse, CNS symptoms, blood dyscrasias, Stevens-Johnson syndrome, liver damage, SI
25
What do you need to teach for patients who are on Hydantoins?
No pregnancy (pregnancy cat D), take calcium and vitamin D, avoid herbs and OTC meds, take at same time each day, keep seizure log, wear medic bracelet, don't drive until Dr. confirms
26
What are Carbamazepines used for?
Epilepsy, seizure
27
What's the therapeutic drug level for Carbamazepine?
4 - 12 mcg/mL
28
What are a/e for Carbamazepine?
Stevens-Johnson Syndrome, SI, hepatotoxicity
29
What do you need to monitor in pt using Carbamazepine?
LFT, CBC, Serum drug level, SI, CNS changes, EKG, electrolytes, lung sounds, edema, seizure precaution
30
What is Donepezil used for?
Alzheimer's and mild to moderate dementia
31
What are some nursing considerations for Donepezil?
It's a cholinergic (SLUDGES)
Assess for improved cognitive function. if not improved, med not working.
Crash cart in case of cholinergic crisis
32
What do you use when pt is experiencing cholinergic crisis?
Atropine
33
Carbidopa/levodopa treats what?
Parkinson's
34
What do you need to teach for pt on carbidopa/levodopa?
Don't stop abruptly, urine and sweat may turn red/brown/black, take with food, avoid high protein diet, change position slowly, avoid activities requiring alertness, avoid multivitamins, notify HCP of a/e, on/off syndrome
35
What do you use Neostigmine for?
To treat Myasthenia Gravis, reverse neuromuscular blockade
36
Excessive muscarinic stimulation and cholinergic crisis is a s/e / a/e of this medication
Neostigmine
37
What's the difference between cholinergic crisis and myasthenic crisis?
Cholinergic is when overmedicated while myasthenic is when undermedicated.
38
What can be used to decide whether pt is experiencing cholinergic or myasthenic crisis?
IV Edrophonium, which is a cholinergic
39
What do you need to provide the pt when giving cholinergics?
Bedpan, urinal (SLUDGES)
40
What drugs are in central-acting muscle relaxants?
Baclofen, Dantrolene, Cyclobenzaprine
41
How do you evaluate central-acting muscle relaxants' effectiveness?
Pt reports decreased pain and increased ROM
42
What are some a/e of neuromuscular blocking drugs?
Respiratory arrest, muscle pain, malignant hyperthermia, hyperkalemia
43
What is the antidote for neuromuscular blocking drug?
Neostigmine
44
Haloperidol and Chlorpromazine are in what drug class?
Typical antipsychotics
45
Haloperidol and chlorpromazine are used for
Acute & chronic psychotic disorder
46
What are some a/e for typical antipsychotics?
Acute dystonia, parkinsonism, akathisia, tardive dyskinesia, neuroleptic malignant syndrome, neuroendocrine, seizures, agranulocytosis, liver impairment, severe dysrhythmias, sexual dysfunction, anticholinergic effects
47
What drugs are in atypical antipsychotics?
Olanzapine, clozapine, risperidone
48
What drug class can cause DM, weight gain, hypercholesterolemia, orthostatic hypotension, elevated prolactin level, and mild EPS?
Atypical antipsychotics
49
What do you need to teach in pt using atypical antipsychotics?
Report abnormal muscle movements, avoid CNS depressants, report s/s DM, diet and exercise, change position slowly, may cause drowsiness, management of anticholinergic effects, may cause seizures
50
What do you need to teach pt on Benzodiazepines?
Can cause dependence (long term), avoid driving and CNS depressants, must be tapered, take with food, take at bedtime, avoid tobacco, caffeine, and sympathomimetics because it decreases effect of benzo
51
What is the most important thing that nurses have to monitor for in patients on antidepressants?
SI. Antidepressants can mask SI
52
What are SSRIs used for?
To treat major depression, OCD, ODD, Bulimia, PTSD, social anxiety, general anxiety
53
Fluoxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, and Paroxetine are in this drug class
SSRIs
54
What are some a/e of SSRIs?
CNS stimulation (don't take at bedtime), sexual dysfunction, weight loss then gain, serotonin syndrome, rash, GI bleed, Bruxism, hyponatremia, withdrawal syndrome, sleepiness
55
What are the nursing considerations for SSRIs?
Assess for SI & adherence.
Poor adherence due to sexual dysfunction
56
Phenelzine is in this drug class
MAOIs
57
What are MAOIs for?
To treat neurotic or atypical depression
58
What are some drug interactions with MAOIs?
Any CNS stimulant, any sympathomimetics, vasopressors, TCAs, SSRIs, general anesthetics
59
What are some food interactions with MAOIs?
Foods high in tyramine.
Aged cheese, beer, red wine, smoked meat, yogurt, coffee, chocolate, pickled foods, yeast, bananas, liver
60
Which antidepressant is known for several drug/food interactions?
MAOIs
61
What are lithium used for?
To decrease mood fluctuations, to treat bipolar disorder
62
What do you need to teach pt on Lithium?
Taper off, it will take days to reach desired effect
63
What's the normal serum drug level for lithium?
0.6 - 1.2 mEq/L
64
Lithium level < 1.5 can manifest
N/V/D, thirst, polyuria, muscle weakness, fine hand tremor, slurred speech, lethargy
65
Lithium level 1.5 - 2 indicates
Early indication of lithium toxicity.
Manifests ongoing GI distress, confusion, poor coordination, coarse tremors, sedation. Hold dose
66
Lithium level 2 - 2.5 indicates
Advanced indication of lithium toxicity.
Extreme polyuria with dilute urine, tinnitus, involuntary extremity movements, blurred vision, ataxia, seizures, severe hypotension, respiratory complications (can lead to death). Emetics, gastric lavage
67
Lithium level > 2.5
Severe toxicity.
Oliguria, seizures, rapid progression of manifestations. Possibly death. Requires hemodialysis
68
Amitriptyline and nortriptyline are in this drug class
TCAs
69
What are the s/a/e of TCAs?
Orthostatic hypotension, anticholinergic effects, sedation, toxicity, decreased seizure threshold, excessive sweating, sexual dysfunction, arrhythmias
70
What drugs are in Anti-gout medications?
Colchicine, Allopurinol, Probenecid
71
What do you need to teach patient taking Anti-gout drugs?
Avoid food high in purine (red meat, alcohol, scallop), increase fluid intake (promote uric acid secretion and prevent kidney stones), take with food, stop if rash occurs, avoid grapefruit juice and salicylates. Can have metallic taste
72
Corticosteroids, Ibuprofen, and Aspirin are in this drug class
NSAIDs
73
What are some a/e of NSAIDs?
Bleeding, GI injury, nephro/hepatotoxic
74
What are some nursing interventions for NSAIDs?
Monitor for bleeding, increase fluid intake, take with food, avoid alcohol and G herbs
75
What are aspirin for?
MI prevention (baby aspirin), decrease inflammation, pain, fever, prevent blood clot
76
Aspirin interacts with these drugs
Warfarin (increase bleeding and absorption)
Alcohol (increase risk of GI bleeding)
G herbs (increase bleeding)
77
What are some a/e of Aspirin?
GI effects, bleeding, nephrotoxicity in high dose, renal impairment, salicylism (overdose), Reye's syndrome (in children with viral illness)
78
What are methotrexate used for?
Slow or delay worsening of RA
79
What drug class is methotrexate in?
DMARDs
80
What are the contraindications of Methotrexate?
Liver failure, alcohol use disorder, blood dyscrasias
81
What drugs are in opioid agonist?
Morphine, fentanyl, codeine, heroin, hydrocodone, hydromorphone, meperidine, methadone, oxycodone, oxymorphone, tramadol
82
What are the a/e of opioid agonists?
Respiratory depression, cardiac arrest, neurotoxicity
83
Naloxone and naltrexone are in this drug class
Opioid antagonist
84
How would you know you need to give naloxone to a patient?
When opioid taking patient's respiration rate decreases
85
What are the general a/e for cephalosporins and penicillin?
Hypersensitivity reactions, bleeding, superinfections, C.diff
86
If patient is allergic to cephalosporins, then it is likely that the patient is also allergic to
Penicillin
87
What are the nursing interventions for Cephalosporins and Penicillins?
History of allergy, C&S before starting, RFT & LFT, s/s superinfection, bleeding. Report bloody diarrhea, multiple liquid stools
88
What are the s/a/e of Vancomycin?
Ototoxicity, Red-man syndrome, nephrotoxicity, Stevens-Johnson syndrome, IV site pain, thrombophlebitis
89
What are some nursing interventions for Vancomycin?
Check serum drug level, infuse over 60 minutes, check hearing, infusion site, s/s superinfection
90
What's the only abx that you don't have to worry about C. diff?
Vancomycin
91
What are fluoroquinolones used for?
Broad spectrum abx
92
What are the a/e of fluoroquinolones?
Achilles tendon rupture, superinfection, crystalluria, hypersensitivity reactions
93
Gentamicin, Tobramycin, Amikacin, Kanamycin, Neomycin, Streptomycin are in this drug class
Aminoglycosides
94
Aminoglycosides have narrow therapeutic index meaning it needs
peak and trough levels
95
INH is used for
TB
96
What are the s/a/e of INH?
Neuropathy, hepatotoxicity, hepatitis
97
INH is taken with what to prevent neuropathy?
Vitamin B6 (pyridoxine)
98
When taking INH, limit the intake of this kind of food
Tyramine high food such as avocados, aged cheese, smoked meat, chocolate, etc.
99
Acyclovir is used for
Herpes simplex viruses, varicella zoster virus (shingles)
It's an anti-viral
100
Fluconazole is used for
Systemic mycoses
101
Tamoxifen is used for
Breast cancer
102
What are the a/e for Tamoxifen?
Endometrial cancer/vaginal bleeding, hypercalcemia, blood clot
103
Epoetin alfa is used to
Increase production of RBC.
For chronic kidney disease, chemo, those taking meds for HIV & AIDs, elective surgeries
104
HTN, risk for thrombotic events, DVT, headache and body ache are s/a/e of
Epoetin alfa
105
Oprelvekin is used to
Increase the production of platelets
To treat thrombocytopenia
106
How do you know if Oprelvekin is effective?
Platelet > 50,000
107
How do decongestants work?
Vasoconstriction
108
Pseudoephedrine and Phenylephrine are in this drug class
Decongestants
109
What are s/a/e of decongestants?
Related to sympathomimetic effects on CNS & cardio systems
110
Decongestants are contraindicated in
Glaucoma and pt with preexisting HTN, cardiac disease, and hyperthyroidism
111
What drugs are in Methylxanthines?
Theophylline and aminophylline
112
What are Methylxanthines used for?
Asthma & bronchospasms
113
What are some drug interactions of Methylxanthines?
Smoking and caffeine
114
What drugs are in Mucolytic?
Acetylcysteine
115
What should you teach about Mucolytics?
It smells like rotten eggs
116
What drugs are in Beta 2 agonist group?
Albuterol, Levalbuterol, Pirbuterol, Arformoterol, Formoterol, Indacaterol
117
What are Beta 2 agonists used for?
Bronchodilate
118
What's the difference between short acting vs long acting Beta 2 agonist?
Rescue drug vs preventing asthma symptoms
119
What should you teach about Beta 2 agonists?
Don't use short-acting more than 2-3 times per week
Use this before using corticosteroids
Use as ordered
Use with spacer
Tolerance can occur
120
What are the a/e of Beta 2 agonists?
Sinus tachycardia, HTN, palpitations, angina
121
How do you recognize inhaled corticosteroids?
Beclomethasone, Budesonide, Flunisolide, Fluticasone, Mometasone, Triamcinolone, Ciclesonide
Steroids usually -one
122
What are inhaled corticosteroids used for?
Maintenance drug for Asthma & COPD
123
What should you teach the patient who uses inhaled corticosteroids?
Rinse mouth after use, use after Beta 2 agonist, use every day. Can take 4 weeks
124
What drugs are in cardiac glycosides?
Digoxin, Digitalis, Digitoxin
125
What are cardiac glycosides used for?
For HF, A.fib, A.flutter
126
What are some s/a/e of cardiac glycosides?
Drug toxicity, cardiotoxicity, GI effects, CNS effects
127
What are some nursing interventions when using cardiac glycosides?
Monitor serum drug level, K+ level, check apical pulse, s/s heart failure, s/s digoxin toxicity
128
What indicates digoxin toxicity?
Apical pulse < 60bpm
129
What is the big risk factor for digoxin toxicity?
Hypokalemia
130
Nitroglycerin, Amyl nitrate, Isosorbide dinitrate, Isosorbide mononitrate are in this drug class
Nitrates
131
What are nitrates used for?
Antianginal; decrease cardiac oxygen demand and vasodilate
132
What are some s/a/e of nitrates?
Headache, Hypotension, dizziness, syncope, flushing, peripheral edema, orthostatic hypotension, reflex tachycardia, palpitations, dyspnea
133
What are contraindicated in nitrate use?
Concurrent use of PDE5 inhibitors (fatal hypotension)
134
What do you need to teach the patient about nitrate transdermal patch?
Usually for chronic angina; so slower than other routes
longer duration of action
date, time, initial
rotate site
Take it off at bedtime to decrease tolerance
135
What drugs are in K+ sparing diuretics?
Spironolactone, Triamterene
136
K+ sparing diuretic is used for
Hypokalemia. Used with other diuretics to help maintain K+ balance
137
What are some s/a/e of K+ sparing diuretics?
Hyperkalemia, dizziness, androgen effects, gynecomastia
138
What are some nursing interventions when using K+ sparing diuretics?
S/S hyperkalemia, avoid K+ rich foods and salt substitutes, check K+ levels
139
What drugs are in Thiazides?
Hydrochlorothiazide (HCTZ), chlorothiazide
140
What are thiazides used for?
Central HTN, edema, HF
141
How do you evaluate the effectiveness of thiazides?
Decreased BP (in normal range), decreased edema, dyspnea, crackles
142
What drugs are in loop diuretics?
Furosemide, Bumetanide
143
What are loop diuretics used for?
CHF, edema, HTN, acute renal failure, acute pulmonary edema, hypertensive crisis
144
What do you need to teach patient on loop diuretic?
Change positions slowly, take in the morning, be ready to go to bathroom, eat K+ rich foods and supplements, s/s hypokalemia, take with food, wear sunscreen, avoid foods high in Na+, keep daily weight and BP log
145
How do you evaluate effectiveness of a loop diuretic?
Decreased BP (in normal range), Decreased edema, dyspnea, crackles.
Same as Thiazides
146
How do you recognize Calcium channel blockers?
Diltiazem, Verapamil, ~dipine
147
What are CCBs for?
Antihypertensive
148
What are a/e of CCB?
Edema, hypotension, bradycardia, CHF
149
What are some nursing considerations for CCB?
VS, EKG, I&O, Daily weight
Labs (LFT, RFT, CBC, Glucose, K+ level)
Edema & flushing
150
What do you need to teach patient on CCB?
Taper dose, report chest pain, avoid statins and grapefruit juice
151
Clonidine is used for
Hypertension. It's an Alpha 2 agonist
152
What do you need to teach patient on Clonidine?
Taper dose, Daily weight, self check BP, I&O, mental depression can occur, swelling legs & feet, vivid dreams/nightmares, It's a transdermal patch; put on same time each day, change every 7 days, rotate site
153
How do you recognize ACE inhibitors?
~pril
154
ACE inhibitors are for
Antihypertensive
155
What are some s/a/e of ACE inhibitors?
Angioedema, Cough, Elevated potassium
156
What do you need to teach patient on ACE inhibitors?
Taper dose, avoid K+ foods and salt substitutes, check BP, blackbox warning for pregnancy.
Cough is a s/e, but if can't tolerate, notify and change to ARBs
157
How do you treat HTN in African Americans?
They don't respond to ACE inhibitors. Treat with diuretics first and add Beta blocker or ACE inhibitor
158
Warfarin is used to treat
DVT, prevent blood clots in pt with A.fib, prosthetic heart valves. Prevent MI, TIA, PE and DVT
159
What labs do you check when using Warfarin?
PT & INR
160
What's the therapeutic level of Warfarin labs?
PT: 1.5 - 2
INR: 2 -3
161
What drug/food interacts with Warfarin?
Highly protein bound drugs
162
What's the antidote for Warfarin?
Vitamin K
163
What does Heparin treat?
Prevents blood clots
164
What are the labs drawn for Heparin?
aPTT/PTT
165
What are the therapeutic levels of Heparin lab?
aPTT: 1.5 - 2
166
What's the antidote for Heparin?
Protamine sulfate
167
How do you recognize HMG-CoA Reductase Inhibitors?
~Statins
168
What are the baseline labs for HMG-CoA Reductase Inhibitors?
Cholesterol: 150-200
HDL: >60
LDL: <100
Triglyceride: 40-150
Liver function (statins can increase level)
Kidney function
Creatine kinase (rhabdomyolysis)
Homocysteine
CRP
Eye exam
169
What are the nursing interventions when using HMG-CoA Reductase Inhibitors?
LFT, s/s hepatotoxicity, CK level for myalgia, avoid grapefruit juice, report muscle pain, take before bedtime, report pregnancy, avoid alcohol, eye exam
170
What are the s/a/e of HMG-CoA Reductase Inhibitors?
Myopathy, hepatotoxicity, rhabdomyolysis, myalgia, GI issues
171
What drug is in surfactant laxative?
Docusate sodium
172
Surfactant laxative is used for
Stool softener; relieve constipation, prevent painful elimination, prevent straining, decreases risk for fecal impaction, promote defecation
173
How does surfactant laxative work?
Allows water to penetrate in poop
174
Lactulose is used for
Lowering ammonia level in patient with portal HTN and hepatic encephalopathy
175
What are the different types of antacids?
Aluminum & calcium compounds: constipation
Magnesium compounds: diarrhea, possible toxicity and hypermagnesemia
Sodium containing: fluid retention
Aluminum hydroxide: hypophosphatemia, hypomagnesemia
176
How does sucralfate work?
Coats mucosa and protects the ulcer
177
How does Misoprostol work?
Increases bicarbonate and mucin release and reduces acid secretion, protects lining of the stomach and helps repair ulcer
178
What drugs are in H2 receptor blockers?
Cimetidine, famotidine (~tidine)
179
What are H2 receptor blockers used for?
First choice of drug for ulcers
180
What are some drug/food interactions of H2 receptor blockers?
Smoking
181
What do you need to teach patient taking H2 receptor blockers?
Eat at regular schedule, don't over eat, avoid spicy food, caffeine, decaf, alcohols, smoking. Rest, avoid stress and NSAIDs, GI bleeding, s/s respiratory infection, take 30-60 min before eating
182
How do you recognize PPIs?
~prazole
183
What are PPIs used for?
Reduces acid secretion and suppress last phase of gastric acid production
184
What are a/e of PPIs?
Headache, N/V/D with short term
PNA, osteoporosis & fractures, rebound acid hypersecretion, hepatotoxicity, hypomagnesemia with long term
185
What drugs are in antithyroid?
Methimazole
186
How do you evaluate effectiveness of antithyroid drugs?
Decrease thyroid level (in normal range)
187
What are glucocorticoids used for?
Replacement therapy to treat Addison's
188
What are some a/e of glucocorticoids?
Suppression of adrenal gland function, Cushing's syndrome, Bone loss/osteoporosis, hyperglycemia and glycosuria, myopathy, PUD, infection, fluid & electrolyte disturbances, growth suppression in children
189
What do you need to teach patients on glucocorticoids?
Take with food, wear medic bracelet, take it every other morning, avoid NSAIDs, don't stop abruptly, perform weight bearing exercises, report s/s infection, muscle weakness, s/s cushing's
190
Levothyroxine is used for
Treat hypothyroidism, goiter
191
When should you take levothyroxine?
First thing in the morning, on an empty stomach
192
How do you recognize bisphosphonates?
~dronate
193
Bisphosphonates are used for
Prophylaxis & treatment of osteoporosis
194
What are the a/e of bisphosphonates?
Esophagitis, esophageal ulceration, visual disturbances, bisphosphonate-related osteonecrosis of the jaw, kidney toxicity
195
What do you need to teach patients on bisphosphonates?
Take on empty stomach, remain upright for 30 minutes, take with 8oz water, report visual changes, avoid dental work
196
What drugs are in sulfonylureas?
Glimepiride, glipizide, glyburide (~ide)
197
What are sulfonylureas used for?
Oral hypoglycemics. Insulin release from the pancreas
198
What are a/e of sulfonylureas?
Hypoglycemia, weight gain
199
What are some nursing considerations & patient teaching when using sulfonylureas?
Monitor s/s hypoglycemia, assess POC glucose, teach pt about snacks (15g carb), keep BG log, take with breakfast
200
What are some s/a/e of Metformin?
weight loss, GI effects, vitamin B12 and folic acid deficiency, lactic acidosis
201
What is Oxybutynin used for?
Decrease urinary incontinence AKA Overactive bladder
It's an anticholinergic
202
What are some contraindications of Oxybutynin?
Glaucoma, myasthenia gravis, paralytic ileus, GI/GU obstruction, urinary retention
203
Bethanechol is used for
Increasing bladder tone; urinary stimulant. It's a cholinergic. Used for nonobstructive urinary retention
204
What are s/a/e of Bethanechol?
SLUDGES, overdose
205
What drugs are in PDE5 inhibitors?
Sildenafil, Tadalafil (~afil). used to treat erectile dysfunction
206
What are the contraindications of PDE5 inhibitors?
Preexisting cardiac disease, hypersensitivity
207
Buthanechol is contraindicated in
Asthma
208
Alpha 1
Dilation of vessels and decrease in BP
209
Tetracycline
Take on empty stomach; iron, calcium, dairy products, antacids, magnesium decreases absorption
210
Sulfa allergy
Contraindicated in hydrochlorothiazide, loop diuretics, sulfonylureas
211
Nitrofurantoin
Observe for bruising on skin, take with milk or meals, expect brown urine
212
Rifampin
Causes bodily fluids to turn red (s/e)
Treatment for TB
213
Ethambutol
Needs baseline and periodic eye exam because it can induce optic neuritis
Part of RIPE
214
Amphotericin B
For serious systemic mycotic disease
High risk of developing nephrotoxicity
215
What's contraindicated in NSAID therapy?
Peptic ulcer disease
216
What's the expected s/e of metformin therapy?
Weight loss
217
This insulin peaks in 1-5 hours
Regular
218
A/e of ACE inhibitors
Hyperkalemia
219
Major s/e of opioids that can become an a/e
Constipation
220
Diuretic with an a/e of HF
Mannitol
221
This indicates salicylate toxicity
Tinnitus
222
A/e of gentamicin and vancomycin
Nephrotoxicity
223
Contraindication to and a/e of epoetin alfa therapy
HTN, blood clot
224
Clonidine transdermal patch should be left on for this period of time
1 week
225
PDE5 + nitrates can cause
Fatal hypotension
226
What's a desired effect of Beta blocker therapy?
Decrease HR
227
This should be avoided in those taking methylxanthines
Caffeine
228
This medication should be taken 1 hour before breakfast and 4 hours before other meds
Levothyroxine
229
Ferrous sulfate should be taken with this to increase absorption
OJ (vitamin C)
230
What can increase pt's risk of lithium toxicity and what should you teach them?
Dehydration, increase fluid intake
231
This antiseizure drug can cause gingival hyperplasia
Phenytoin
232
Potentially serious a/e of clozapine
Agranulocytosis
233
Evaluate effectiveness of donepezil
Assess LOC
