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Pharm > Pharm Exam 2 > Flashcards

Pharm Exam 2 Flashcards

1
Q

oxybutynin

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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2
Q

oxybutynin transdermal/ oxybutynin topical

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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3
Q

darifenacin

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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4
Q

solifenacin

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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5
Q

tolterodine

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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6
Q

fesoterodine

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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7
Q

trospium

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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8
Q

flavoxate

A

anti-muscarinic used to treat overactive bladder (antispasmodic)

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9
Q

mirabegron

A

beta 3 adrenergic agonist used to treat overactive bladder (antispasmodic)

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10
Q

imipramine

A

tricyclic antidepressant; off-label use for nocturnal enuresis used to treat overactive bladder (antispasmodic)

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11
Q

hyosyamine

A

anti-cholinergic used to treat overactive bladder and bladder spasms (antispasmodic)

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12
Q

Botox

A

inhibits acetylcholine release from nerve ending, used to treat overactive bladder (antispasmodic)

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13
Q

bethanechol

A

cholinergic agonist used to treat urinary retention by increasing detrusor muscle tone and GI motility

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14
Q

neostigmine

A

cholinesterase inhibitor used to treat urinary retention by increasing detrusor muscle tone

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15
Q

finasteride

A

5alpha-reductase inhibitor (anti-dihydrotestosterone) used to treat BPH

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16
Q

dutasteride

A

5alpha-reductase inhibitor (anti-dihydrotestosterone) used to treat BPH

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17
Q

dutasteride/tamsulosin

A

5alpha-reductase inhibitor (anti-dihydrotestosterone) +selective alpha1-a adrenergic blocker; used to treat BPH

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18
Q

tamsulosin

A

selective alpha1-a adrenergic blocker; used to treat BPH

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19
Q

alfuzosin

A

selective alpha1-a adrenergic blocker; used to treat BPH

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20
Q

silodosin

A

selective alpha1-a adrenergic blocker; used to treat BPH

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21
Q

doxazosin

A

selective alpha1 adrenergic blocker; used to treat BPH

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22
Q

terazosin

A

selective alpha1 adrenergic blocker; used to treat BPH

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23
Q

prazosin

A

selective alpha1 adrenergic blocker; used to treat BPH

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24
Q

Saw Palmetto

A

herbal remedy used to treat BPH

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25
Q

-afil suffix

A

phosphodiesterase-5 inhibitor

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26
Q

tadalafil

A

phosphodiesterase-5 inhibitor; used to treat erectile dysfunction; effective for men with both ED and urinary symptoms

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27
Q

vardenafil

A

phosphodiesterase-5 inhibitor; used to treat erectile dysfunction

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28
Q

sildenafil

A

phosphodiesterase-5 inhibitor; used to treat erectile dysfunction

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29
Q

avanafil

A

phosphodiesterase-5 inhibitor; used to treat erectile dysfunction

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30
Q

yohimbine

A

alpha2 adrenergic antagonist used to treat erectile dysfunction

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31
Q

alprostadil intracavernous

A

used to treat erectile dysfunction

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32
Q

alprostadil urethral

A

used to treat erectile dysfunction

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33
Q

tamsulosin

A

alpha1a adrenergic blocker; used to treat nephrolithiasis

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34
Q

allopurinol

A

used to treat nephrolithiasis (and gout)

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35
Q

Sodium phosphate/potassium phosphate

A

used to treat nephrolithiasis and phosphorous replacement

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36
Q

Penacillamine

A

prevents cysteine cacluli; also treats Wilson Dz; RA

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37
Q

Potassium citrate

A

alkalizes the urine to treat nephrolithiasis

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38
Q

Potassium acid phosphate

A

acidifies the urine used to treat nephrolithiasis

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39
Q

Phenazopyridine

A

analgesic used to treat dysuria

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40
Q

lidocaine jelly

A

urethral anasthetic; inhibits Na channels;

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41
Q

Rimso-50

A

anti-inflammatory, antioxidant, and analgesic effects used to treat interstitial cystitis

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42
Q

Elmiron

A

adheres to bladder wall/serves as a buffer; used to treat interstitial cystitis

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43
Q

Fibanserin

A

used to treat female sexual dysfunction

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44
Q

hydrochlorothiazide

A

thiazide diuretics used to treat hypertension

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45
Q

chlorthiazide

A

thiazide diuretics used to treat hypertension

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46
Q

chlorthalidone

A

thiazide diuretics used to treat hypertension

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47
Q

indapamide

A

thiazide diuretics used to treat hypertension

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48
Q

metolazone

A

thiazide diuretics used to treat hypertension

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49
Q

methyclothiazide

A

thiazide diuretics used to treat hypertension

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50
Q

furosemide

A

loop diuretic; used to treat hypertension

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51
Q

torsemide

A

loop diuretic; used to treat hypertension

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52
Q

ethacrynic acid

A

loop diuretic; used to treat hypertension

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53
Q

bumetanide

A

loop diuretic; used to treat hypertension

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54
Q

spironolactone

A

aldosterone antagonist used to treat hypertension

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55
Q

spironolactone/HTCZ (Aldactazide)

A

aldosterone antagonist + Thiazide diuretics; used to treat hypertension

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56
Q

eplerenone

A

aldosterone antagonist; used to treat hypertension

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57
Q

triamterene

A

epithelial Na channel antagonist; used to treat hypertension

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58
Q

triamterene/HCTZ

A

epithelial Na channel antagonist + thiazide diuretic; used to treat hypertension

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59
Q

amiloride

A

epithelial Na channel antagonist; used to treat hypertension

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60
Q

amiloride/HCTZ

A

epithelial Na channel antagonist + thiazide diuretic; used to treat hypertension

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61
Q

-pril suffix

A

Ace-Inhibitor

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62
Q

benazepril

A

Ace-Inhibitor; used to treat hypertension

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63
Q

benazepril/HCTZ

A

Ace-Inhibitor + thiazide diuretic; used to treat hypertension

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64
Q

lisinopril

A

Ace-Inhibitor; used to treat hypertension

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65
Q

lisinopril/HCTZ

A

Ace-Inhibitor + Thiazide diuretic; used to treat hypertension

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66
Q

enalapril

A

Ace-Inhibitor; used to treat hypertension

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67
Q

enalaprilat

A

Ace-Inhibitor; used to treat hypertension Used in emergencies

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68
Q

enalapril/HCTZ

A

Ace-Inhibitor + thiazide diuretic; used to treat hypertension

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69
Q

fosinopril

A

Ace-Inhibitor; used to treat hypertension

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70
Q

moexipril

A

Ace-Inhibitor; used to treat hypertension

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71
Q

perindopril

A

Ace-Inhibitor; used to treat hypertension

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72
Q

perindopril/amlodipine

A

Ace-Inhibitor + Ca channel blocker (dihydropyridine); used to treat hypertension

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73
Q

quinapril

A

Ace-Inhibitor; used to treat hypertension

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74
Q

ramipril

A

Ace-Inhibitor; used to treat hypertension

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75
Q

trandolapril

A

Ace-Inhibitor; used to treat hypertension

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76
Q

trandolapril/HCTZ

A

Ace-Inhibitor + thiazide diuretic; used to treat hypertension

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77
Q

captopril

A

Ace-Inhibitor; used to treat hypertension

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78
Q

-sartan suffix

A

angiotensin 2 receptor antagonist

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79
Q

azilsartan

A

angiotensin 2 receptor antagonist; used for hypertension

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80
Q

azilsartan/chlorthalidone

A

angiotensin 2 receptor antagonist + thiazide diuretic; used for hypertension

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81
Q

candesartan

A

angiotensin 2 receptor antagonist; used for hypertension

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82
Q

valsartan

A

angiotensin 2 receptor antagonist; used for hypertension

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83
Q

valsartan/HCTZ

A

angiotensin 2 receptor antagonist + thiazide diuretic; used for hypertension

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84
Q

losartan

A

angiotensin 2 receptor antagonist; used for hypertension

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85
Q

losartan/HCTZ

A

angiotensin 2 receptor antagonist + thiazide diuretic; used for hypertension

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86
Q

irbesartan

A

angiotensin 2 receptor antagonist; used for hypertension

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87
Q

olmesartan

A

angiotensin 2 receptor antagonist; used for hypertension

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88
Q

olmesartan/HCTZ

A

angiotensin 2 receptor antagonist + thiazide diuretic; used for hypertension

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89
Q

telmisartan

A

angiotensin 2 receptor antagonist; used for hypertension

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90
Q

telmisartan/amlodipine

A

angiotensin 2 receptor antagonist + Ca channel blocker; used for hypertension

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91
Q

eprosartan

A

angiotensin 2 receptor antagonist; used for hypertension

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92
Q

aliskiren

A

direct renin inhibitor; used for hypertension

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93
Q

aliskiren/HCTZ

A

direct renin inhibitor + thiazide diuretic; used for hypertension

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94
Q

aliskiren/amlodipine

A

direct renin inhibitor + Ca channel blocker; used for hypertension

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95
Q

aliskiren/amlodipine/HCTZ

A

direct renin inhibitor + Ca channel blocker + thiazide diuretic; used for hypertension

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96
Q

-dipine suffix

A

dihydropyridine Ca channel blocker

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97
Q

amlodipine

A

dihydropyridine Ca channel blocker

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98
Q

amlodapine/benzepril

A

CCB+ACEI; used for hypertension

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99
Q

amlodipine/olmesartan

A

CCB/ARB used for hypertension

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100
Q

amlodipine/olmesartan/HCTZ

A

CCB/ARB/thiazide diuretic used for hypertension

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101
Q

amlodapine/valsartan

A

CCB/ARB used for hypertension

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102
Q

amlodapine/valsartan/HCTZ

A

CCB/ARB/thiazide diuretic used for hypertension

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103
Q

amlodapine/atorvastain

A

CCB/statin; used for hypertension

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104
Q

isradipine

A

dihydropyridine CCB

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105
Q

felodipine

A

dihydropyridine CCB

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106
Q

nisoldipine

A

dihydropyridine CCB

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107
Q

nifedipine

A

dihydropyridine CCB

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108
Q

nicardipine

A

dihydropyridine CCB Used in emergencies

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109
Q

clevidipine

A

dihydropyridine CCB

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110
Q

verapamil

A

non-dihydropyridine CCB

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111
Q

ditiazem

A

non-dihydropyridine CCB

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112
Q

-olol suffix

A

selective beta 1 blocker

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113
Q

atenolol

A

selective beta 1 blocker; used for hypertension

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114
Q

atenolol/chlorthalidone

A

selective beta 1 blocker + thiazide diuretic; used for hypertension

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115
Q

acebutolol

A

selective beta 1 blocker; used for hypertension

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116
Q

betaxolol

A

selective beta 1 blocker; used for hypertension

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117
Q

bisoprolol

A

selective beta 1 blocker; used for hypertension

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118
Q

esmolol

A

selective beta 1 blocker; used for hypertension Used in emergencies

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119
Q

metoprolol succinate

A

selective beta 1 blocker; used for hypertension

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120
Q

metoproplol succinate/ HCTZ

A

selective beta 1 blocker + thiazide diuretic; used for hypertension

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121
Q

metoprolol tartrate

A

selective beta 1 blocker; used for hypertension

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122
Q

metoprolol tartrate/HCTZ

A

selective beta 1 blocker + thiazide diuretic; used for hypertension

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123
Q

nebivolol

A

selective beta 1 blocker; used for hypertension

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124
Q

carvedilol

A

alpha1 beta1 beta2 blocker

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125
Q

labetalol

A

alpha1 beta1 beta2 blocker Used in hypertensive emergencies

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126
Q

nadolol

A

non-selective beta blocker

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127
Q

penbutolol

A

non-selective beta blocker

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128
Q

pindolol

A

non-selective beta blocker

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129
Q

propanolol

A

non-selective beta blocker

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130
Q

timolol

A

non-selective beta blocker

131
Q

-azosin suffix

A

selective alpha 1 blocker

132
Q

doxazosin

A

selective alpha 1 blocker

133
Q

prazosin

A

selective alpha 1 blocker

134
Q

terazosin

A

selective alpha 1 blocker

135
Q

nitroprusside

A

vasodilator Used in hypertensive emergencies

136
Q

nitroglycerin

A

vasodilator Used in emergencies

137
Q

hydralazine

A

vasodilator Used in emergencies

138
Q

minoxidil

A

vasodilator

139
Q

fenoldopam

A

vasodilator; Used in hypertensive emergencies

140
Q

clonidine

A

alpha2 agonist (central-acting anti-hypertensive)

141
Q

clonidine/chlorthalidone

A

alpha2 agonist (central-acting anti-hypertensive) + thiazide diuretic

142
Q

guanfacine

A

alpha2 agonist (central-acting anti-hypertensive)

143
Q

methyldopa

A

alpha2 agonist (central-acting anti-hypertensive)

144
Q

phentolamine

A

non-selective alpha blocker Used in emergencies

145
Q

acetazolamide

A

Carbonic anhydrase inhibitor; used as diuretic

146
Q

mannitol

A

osmotic diuretic; used as diuretic

147
Q

furosemide

A

loop diuretic; used as diuretic

148
Q

torsemide

A

loop diuretic; used as diuretic

149
Q

ethacrynic acid

A

loop diuretic; used as diuretic

150
Q

bumetanide

A

loop diuretic; used as diuretic

151
Q

hydrochlorothiazide

A

thiazide diuretic; used as diuretic

152
Q

chlorthalidone

A

thiazide diuretic; used as diuretic

153
Q

chlorthiazide

A

thiazide diuretic; used as diuretic

154
Q

indapamide

A

thiazide diuretic; used as diuretic

155
Q

metolazone

A

thiazide diuretic; used as diuretic

156
Q

methyclothiazide

A

thiazide diuretic; used as diuretic

157
Q

spironolactone

A

Steroid (aldosterone) antagonist, potassium-sparing diuretic

158
Q

eplerenone

A

Steroid (aldosterone) antagonist, Potassium-sparing diuretic

159
Q

triamterene

A

epithelial Na channel antagonist; potassium-sparing diuretic

160
Q

amiloride

A

epithelial Na channel antagonist; potassium-sparing diuretic

161
Q

conivaptan

A

ADH antagonist, collecting duct diuretic

162
Q

tolvaptan

A

ADH antagonist, collecting duct diuretic

163
Q

pamabrom

A

methylxanthine stimulant promotes diuresis by antagonizing adenosine receptors

164
Q

-statin suffix

A

HMG CoA reductase inhibitor-Statin

165
Q

lovastatin

A

HMG CoA reductase inhibitor-Statin

166
Q

simvastatin

A

HMG CoA reductase inhibitor-Statin

167
Q

atorvastatin

A

HMG CoA reductase inhibitor-Statin

168
Q

rosuvastatin

A

HMG CoA reductase inhibitor-Statin

169
Q

pravastatin

A

HMG CoA reductase inhibitor-Statin

170
Q

fluvastatin

A

HMG CoA reductase inhibitor-Statin

171
Q

pitavastatin

A

HMG CoA reductase inhibitor-Statin

172
Q

ezetimibe

A

Cholesterol absorption inhibitor

173
Q

ezetimibe/simvastatin

A

Cholesterol absorption inhibitor + HMG CoA reductase inhibitor-Statin

174
Q

contains fibr root

A

fibric acid derivative

175
Q

gemfibrozil

A

fibric acid derivative

176
Q

fenofibrate

A

fibric acid derivative

177
Q

fenofibric acid

A

fibric acid derivative

178
Q

fenofibrate micronized

A

fibric acid derivative

179
Q

contains nia root

A

nicotinic acid derivative

180
Q

niacin

A

nicotinic acid derivative

181
Q

niacin/simvastatin

A

nicotinic acid derivative + HMG CoA reductase inhibitor-Statin

182
Q

Niaspan

A

nicotinic acid derivative

183
Q

Sio-Niacin

A

nicotinic acid derivative

184
Q

omega 3 ethyl esters

A

omega 3 fatty acids

185
Q

col or chol root

A

bile acid sequesterants

186
Q

colesevelam

A

bile acid sequesterants

187
Q

cholestyramine

A

bile acid sequesterants

188
Q

colestipol

A

bile acid sequesterants

189
Q

icosapent ethyl

A

reduces hepatic triglyceride synthesis; used to treat severe hypertriglyceridemia

190
Q

lomitapide

A

used to treat homozygous familial hypercholesterolemia; also used to treat atherosclerotic cardiovascular disease

191
Q

alirocumab

A

PSK9 inhibitor used to treat heterozygous familial hypercholesterolemia; also used to treat atherosclerotic cardiovascular disease

192
Q

evolocumab

A

PSK9 inhibitor used to treat homozygous and heterozygous familial hypercholesterolemia; also used to treat atherosclerotic cardiovascular disease

193
Q

quinidine

A

Class 1A (sodium channel blocker) anti-arrhythmic

194
Q

procainamide

A

Class 1A (sodium channel blocker) anti-arrhythmic

195
Q

disopyramide

A

Class 1A (sodium channel blocker) anti-arrhythmic

196
Q

lidocain

A

Class 1B (sodium channel blocker) anti-arrhythmic

197
Q

mexiletine

A

Class 1B (sodium channel blocker) anti-arrhythmic

198
Q

flecainide

A

Class 1C (sodium channel blocker) anti-arrhythmic

199
Q

propafenone

A

Class 1C (sodium channel blocker) anti-arrhythmic

200
Q

acebutolol

A

Class 2 (beta blockers) anti-arrhythmic

201
Q

esmolol

A

Class 2 (beta blockers) anti-arrhythmic

202
Q

propanolol

A

Class 2 (beta blockers) anti-arrhythmic

203
Q

nadolol

A

Class 2 (beta blockers) anti-arrhythmic

204
Q

amiodarone

A

Class 3 (potassium channel blocker) anti-arrhythmic

205
Q

iubutilide

A

Class 3 (potassium channel blocker) anti-arrhythmic

206
Q

sotalol

A

Class 3 (potassium channel blocker) anti-arrhythmic

207
Q

dofetilide

A

Class 3 (potassium channel blocker) anti-arrhythmic

208
Q

dronedarone

A

Class 3 (potassium channel blocker) anti-arrhythmic

209
Q

verapamil

A

Class 4 (calcium channel blocker) anti-arrhythmic

210
Q

diltiazem

A

Class 4 (calcium channel blocker) anti-arrhythmic

211
Q

adenosine

A

anti-arrhythmic

212
Q

digoxin

A

anti-arrhythmic

213
Q

magnesium sulfate

A

anti-arrhythmic

214
Q

epinephrine

A

anti-arrhythmic; ACLS, VF/pulseless VT

215
Q

atropine

A

anti-arrhythmic; acute reversal of AV block

216
Q

isoproterenol

A

anti-arrhythmic; acute reversal of AV block

217
Q

cilostazol

A

PDE 3 Inhibitor; reduces platelet aggregation and supresses cAMP degredation which promotes vasodilation; used for PVD

218
Q

pentoxifylline

A

Lowers blood viscosity and improves erythrocyte flexibility; used for PVD

219
Q

nitroglycerin

A

vasodilator used for angina and CHF

220
Q

isosorbide dinitrate

A

vasodilator used for angina and CHF

221
Q

isosorbide mononitrate

A

vasodilator used for angina and CHF

222
Q

diltiazem

A

calcium channel blocker used for angina and CHF

223
Q

verapamil

A

calcium channel blocker used for angina and CHF

224
Q

nifedipine

A

calcium channel blocker used for angina and CHF

225
Q

nicardipine

A

calcium channel blocker used for angina and CHF

226
Q

amlodipine

A

calcium channel blocker used for angina and CHF

227
Q

atenolol

A

selective beta 1 blocker used for angina and CHF

228
Q

metoprolol succinate

A

selective beta 1 blocker used for angina and CHF

229
Q

metoprolol tartrate

A

selective beta 1 blocker used for angina and CHF

230
Q

bisoprolol

A

selective beta 1 blocker used for angina and CHF

231
Q

nadolol

A

non-selective beta-blocker used for angina and CHF

232
Q

propanolol

A

non-selective beta-blocker used for angina and CHF

233
Q

timolol

A

non-selective beta-blocker used for angina and CHF

234
Q

pindolol

A

non-selective beta-blocker used for angina and CHF

235
Q

aspirin

A

antiplatelet used for angina and CHF

236
Q

clopidogrel

A

antiplatelet used for angina and CHF

237
Q

abciximab

A

antiplatelet used for angina and CHF

238
Q

heparin

A

anticoagulant used for angina an CHF

239
Q

enoxaparin

A

anticoagulant used for angina an CHF

240
Q

ranolazine

A

used for chronic angina

241
Q

ivabradine

A

used for chronic HF and stable angina

242
Q

furosemide

A

loop diuretic used for HF

243
Q

bumetanide

A

loop diuretic used for HF

244
Q

torsemide

A

loop diuretic used for HF

245
Q

chlorthalidone

A

thiazide diuretic used for HF

246
Q

hydrochlorothiazide

A

thiazide diuretic used for HF

247
Q

metolazone

A

thiazide diuretic used for HF

248
Q

spironolactone

A

aldosterone antagonist diuretic used for HF

249
Q

eplerenone

A

aldosterone antagonist diuretic used for HF

250
Q

carvedilol

A

alpha 1, beta 1, beta 2 blocker used for HF

251
Q

metoprolol succinate

A

selective beta 1 blocker used for HF

252
Q

bisoprolol

A

selective beta 1 blocker used for HF

253
Q

captopril

A

ACEI used for HF

254
Q

enalapril

A

ACEI used for HF

255
Q

lisinopril

A

ACEI used for HF

256
Q

ramipril

A

ACEI used for HF

257
Q

quinapril

A

ACEI used for HF

258
Q

benazepril

A

ACEI used for HF

259
Q

candesartan

A

ARB used for HF

260
Q

valsartan

A

ARB used for HF

261
Q

digoxin

A

inotrope/pressor (Na K ATPase inhibitor) used for HF

262
Q

digoxin immune Fab

A

used to treat digoxin intoxication

263
Q

nitroglycerin

A

vasodilator used to treat HF

264
Q

nitroprusside

A

vasodilator used to treat HF

265
Q

isosorbide dinitrate/hydralzine

A

vasodilator combo used for HF

266
Q

isosorbide dinitrate

A

vasodilator used to treat HF

267
Q

hydralazine

A

vasodilator used to treat HF

268
Q

dobutamine

A

beta-1 agonist inotrope/pressor used for decompensated HF

269
Q

dopamine

A

beta 1, alpha 1, d1 agonist used for refractory CHF

270
Q

milirone

A

ionotrope/pressor (inhibits cAMP PDE3) used for CHF

271
Q

ivabradine

A

used for chronic HF; blocks hyperpolarization-activated cyclic nucleotide-gated channels in SA; this selectively inhibits pacemaker current to decrease HR

272
Q

sacubitril/valsartan

A

used for chronic HF

273
Q

nesiritide

A

used for acutely decompensated CHF; stimulates cGMP production which results in vascular smooth muscle relaxation

274
Q

aspirin

A

COX inhibitor used as antiplatelet

275
Q

aspirin/dipyridamole

A

COX inhibitor and adenosine reuptake inhibitor used for antiplatelet purpose and as thrombotic stroke prevention

276
Q

aspirin/omeprazole

A

COX inhibitor and proton pump inhibitor used for antiplatelet

277
Q

clopidogrel

A

ADP receptor inhibitor (thienopyridine); used for antiplatelet

278
Q

prasugrel

A

ADP receptor inhibitor (thienopyridine); used for antiplatelet

279
Q

ticagrelor

A

ADP receptor inhibitor (thienopyridine); used for antiplatelet

280
Q

dipyridamole

A

Adenosine reuptake inhibitor; used for thromboembolism prevention and as antiplatelet

281
Q

vorpaxar

A

protease-activated receptor-1 antagonist (PAR-1); used for antiplatelet

282
Q

abciximab

A

Glycoprotein 2B/3A inhibitor; used for antiplatelet

283
Q

eptifibatide

A

Glycoprotein 2B/3A inhibitor; used for antiplatelet

284
Q

tirofiban

A

Glycoprotein 2B/3A inhibitor; used for antiplatelet

285
Q

cilostazol

A

PDE3 inhibitor; reduces platelet aggregation, suppresses cAMP degradation, produces vasodilation; used for antiplatelet

286
Q

warfarin

A

inhibits vitamin K-dependent coagulation factor synthesis (thrombin 2, VII, IX, X, protein C and S); anticoagulant

287
Q

heparin

A

binds to antithrombin III, catalyzing inactivation of clotting factors (thrombin IIa, Xa, IXa, XIa, XIIa); anticoagulant

288
Q

enoxaprin

A

binds to antithrombin II and accelerates activity inhibiting (thrombin and Xa); low molecular weight heparins; anticoagulant

289
Q

dalteparin

A

binds to antithrombin II and accelerates activity inhibiting (thrombin and Xa); low molecular weight heparins; anticoagulant

290
Q

-xaban suffix

A

oral Xa inhibitor; selective active site inhibitor, does not require antithrombin; anticoagulant

291
Q

apixaban

A

oral Xa inhibitor; selective active site inhibitor, does not require antithrombin; anticoagulant

292
Q

betrixban

A

oral Xa inhibitor; selective active site inhibitor, does not require antithrombin; anticoagulant

293
Q

rivaroxaban

A

oral Xa inhibitor; selective active site inhibitor, does not require antithrombin; anticoagulant

294
Q

edoxaban

A

oral Xa inhibitor; selective active site inhibitor, does not require antithrombin; anticoagulant

295
Q

fondaparinux

A

parenteral Xa inhibitor; antithrombin III-mediated; anticoagulant

296
Q

dabigatran

A

Direct Thrombin inhibitor

297
Q

argatroban

A

Direct Thrombin inhibitor

298
Q

bivalirudin

A

Direct Thrombin inhibitor

299
Q

desirudin

A

Direct Thrombin inhibitor

300
Q

idarucizumab

A

reversal agent for dabigatran; binds dabigatran and its metabolites

301
Q

protamine sulfate

A

used for Heparin overdose and off-label for LMWH reversal; ionically binds heparin, forms stable complex which neutralizes anticoagulant effects

302
Q

-plase suffix

A

fibrinolytic drug used for thrombolytics

303
Q

tenecteplase

A

fibrinolytic; binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis (tPA)

304
Q

alteplase

A

fibrinolytic; binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis (tPA)

305
Q

alteplase intracathter

A

fibrinolytic; binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis (tPA)

306
Q

reteplase

A

fibrinolytic; binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis (tPA)

307
Q

streptokinase

A

fibrinolytic; binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis (tPA)

308
Q

defibrotide

A

enhances enzymatic activity to hydrolize fibrin clots; used to treat hepatobiliary veno-occlusive dz

309
Q

begins with feru, ferrous, or iron

A

iron supplement used for anemia

310
Q

ferrous sulfate

A

iron supplement used for anemia

311
Q

ferrous gluconate

A

iron supplement used for anemia

312
Q

ferrous fumerate

A

iron supplement used for anemia

313
Q

ferumoxytol

A

iron supplement used for anemia

314
Q

iron dextran

A

iron supplement used for anemia

315
Q

iron sucrose

A

iron supplement used for anemia

316
Q

begins with defer

A

iron chelating agent used to treat iron overload

317
Q

defoxamine

A

iron chelating agent used to treat iron overload

318
Q

deferiprone

A

iron chelating agent used to treat iron overload

319
Q

deferasirox

A

iron chelating agent used to treat iron overload

320
Q

cyanocobalamin

A

vitamin b12 supplement

321
Q

folic acid

A

vitamin b9 supplement

322
Q

-poetin suffix

A

erythropoiesis stimulating agent

323
Q

epoetin alfa

A

erythropoiesis stimulating agent

324
Q

darbepoetin alfa

A

erythropoiesis stimulating agent

Pharm (5 decks)

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