Pharm 4 Flashcards

1
Q

beta-lactam antibiotic MOA

A

inhibits cell wall synthesis

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2
Q

-cillin

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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3
Q

Penicillin G

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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4
Q

Penicillin V

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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5
Q

Oxacillin

A

anti-staph penicillin; beta-lactam

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6
Q

Dicloxacillin

A

anti-staph penicillin; beta-lactam

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7
Q

Naficillin

A

anti-staph penicillin; beta-lactam

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8
Q

Ampicillin

A

broad spectrum penicillin; beta-lactam

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9
Q

Amoxicillin

A

broad spectrum penicillin; beta-lactam

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10
Q

Ticaricillin

A

anti-pseudomonal penicillin; beta-lactam

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11
Q

Piperacillin

A

anti-pseudomonal penicillin; beta-lactam

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12
Q

Clavulanic acid

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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13
Q

Sulbactam

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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14
Q

Tazobactam

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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15
Q

Probenecid

A

blocks tubular transport increasing plasma penicillin levels; used in combo with beta-lactam drug

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16
Q

“cefs”

A

Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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17
Q

Cephalexin

A

1st gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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18
Q

Cefazolin

A

1st gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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19
Q

Cefaclor

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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20
Q

Cefuroxime axetil

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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21
Q

Cefuroxime sodium

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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22
Q

Cefoxitin

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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23
Q

Cefiditoren pivoxil

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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24
Q

Cefidinir

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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25
Ceftibuten
3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
26
Ceflixime
3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
27
Ceftriaxone
3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
28
Ceftazidime sodium
3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
29
Cefepime
4th gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
30
Ceftaroline fosamil
5th gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis
31
"penems"
Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis
32
Meropenem
Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis
33
Doripenem
Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis
34
Imipenem/Cilastatin
Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis; + inhibitor of renal dihydropeptidase 1 preventing penem degradation
35
Ertapenem
Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis
36
Cilastatin
inhibitor of renal dihydropeptidase 1 preventing penem degradation
37
Monobactam drugs
beta-lactam antibiotic; inhibitor of cell wall synthesis
38
Aztreonam
Monobactam; beta-lactam antibiotic; inhibitor of cell wall synthesis
39
Glycopeptide
beta-lactam antibiotic; inhibitor of cell wall synthesis ***and inhibits RNA synthesis***
40
Vancomycin
Glycopeptide beta-lactam antibiotic; inhibitor of cell wall synthesis ***and inhibits RNA synthesis***
41
Lipoglycopeptide
beta-lactam antibiotic; inhibitor of cell wall synthesis
42
Telavancin
Lipoglycopeptide; beta-lactam antibiotic; inhibitor of cell wall synthesis
43
Sulfonamides
Folic acid synthesis inhibitor; inhibits metabolism
44
Sulfamethoxazole/Trimethoprim
Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism
45
Sulfisoxazole
Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism
46
Sulfacetamide topical
Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism
47
Sulfacetamide opthalmic
Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism
48
Silver sulfadiazine
Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism; used for burns
49
Trimethoprim
inhibits dihydrofolate reductase; this inhibits folic acid reduction
50
"floxacin" drugs
Quinolones; inhibits nucleic acid synthesis or function
51
Quinolone drugs
inhibits nucleic acid synthesis or function
52
Ciprofloxacin
Quinolone; inhibits nucleic acid synthesis or function
53
Levoflaxacin
Quinolone; inhibits nucleic acid synthesis or function
54
Moxifloxacin
Quinolone; inhibits nucleic acid synthesis or function
55
Gemfloxacin
Quinolone; inhibits nucleic acid synthesis or function
56
Ofloxacin
Quinolone; inhibits nucleic acid synthesis or function
57
Besifloaxacin opthalmic
Quinolone; inhibits nucleic acid synthesis or function
58
"sulfa" drugs
Sulfonamides; Folic acid synthesis inhibitor; inhibits
59
Rifamycins
inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis
60
"Rifa" drugs
Rifamycins; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis
61
Rifampin
Rifamycin; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis
62
"cycline drugs"
Tetracylcine or glycylcycline; inhibitors of protein synthesis
63
Tetracylcine drugs
inhibitors of protein synthesis
64
Doxycycline
Tetracycline; inhibitor of protein synthesis
65
Minocycline
Tetracycline; inhibitor of protein synthesis
66
Tetracycline
Tetracycline; inhibitor of protein synthesis
67
Tigecycline
Glycylcycline; inhibitor of protein synthesis
68
Aminogycoside drugs
Inhibitors of protein synthesis
69
Amikacin
Aminogycosides; Inhibitors of protein synthesis
70
Gentamicin
Aminogycosides; Inhibitors of protein synthesis
71
Neomycin
Aminogycosides; Inhibitors of protein synthesis
72
Paromomycin
Aminogycosides; Inhibitors of protein synthesis
73
Streptomycin
Aminogycosides; Inhibitors of protein synthesis
74
Tobramycin
Aminogycosides; Inhibitors of protein synthesis
75
Macrolide drugs
Inhibitors of protein synthesis
76
Azithromycin
Macrolide; Inhibitors of protein synthesis
77
Erythromycin
Macrolide; Inhibitors of protein synthesis
78
Clarithromycin
Macrolide; Inhibitors of protein synthesis
79
Telithromycin
Ketolide drug (Macrolide); Inhibitors of protein synthesis
80
Lincosamide drugs
Inhibitors of protein synthesis
81
Clindamycin
Lincosamide; Inhibitor of protein synthesis
82
Lincomycin
Lincosamide; Inhibitor of protein synthesis
83
Streptogramin drugs
Inhibitor of protein synthesis
84
Quinupristin/Dalfopristin (Synercid)
Streptogramin drug; inhibitor of protein synthesis
85
Oxazolidinone drugs
Inhibitor of protein synthesis
86
Linezolid
Oxazolidinone; Inhibitor of protein synthesis
87
Mupirocin
binds to isoleucyl-tRNA synthetase, inhibiting protein synthesis
88
Isoniazid
TB drug; inhibits mycolic acid synthesis, disrupting cell wall
89
Rifampin
TB drug; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis
90
Pyrazinamide
TB drug; inhibits mycobacterial growth
91
Ethambutol
TB drug; inhibits metabolite synthesis
92
Clarithrromycin
TB drug; Mycobacterium Avium Complex (MAC) drug; Macrolide; Inhibitors of protein synthesis
93
Azithromycin
TB drug; Mycobacterium Avium Complex (MAC) drug; Macrolide; Inhibitors of protein synthesis
94
Nystatin
Polyene antifungal; oral
95
Amphotericin B
Polyene antifungal; IV
96
Nystatin topical
Polyene antifungal; topical
97
Azole drugs
Imidazole (most likely) or Triazole drug
98
Ketoconazole
Imidazole antifungal; oral
99
Micoconazole oropharyngeal
Imidazole antifungal; for oral candidiasis
100
Clotrimazole
Imidazole antifungal; for oral candidiasis
101
Butoconazole vaginal
Imidazole antifungal; vaginal
102
Tioconazole vaginal
Imidazole antifungal; vaginal
103
Clotrimazole topical
Imidazole antifungal; topical
104
Econazole topical
Imidazole antifungal; topical
105
Ketaconazole topical
Imidazole antifungal; topical
106
Miconazole topcial
Imidazole antifungal; topical
107
Itraconazole
Triazole antifungal
108
Fluconazole
Triazole antifungal
109
"fine" drugs
Allylamine antifungal
110
Terbinafine
Allylamine antifungal; oral
111
Butenafine topical
Allylamine antifungal; topical
112
Naftifine topical
Allylamine antifungal; topical
113
Terbinafine topical
Allylamine antifungal; topical
114
"fungin" drugs
Echinocandin antifungal
115
Andidulafungin
Echinocandin antifungal; IV
116
Caspofungin
Echinocandin antifungal; IV
117
Micafungin
Echinocandin antifungal; IV
118
Flucytosine
antifungal; oral
119
Griseofulvin
antifungal; oral
120
Ciclopirox topical
antifungal; topical
121
Tolnaflate topical
antifungal; topical
122
Zidovudine
Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)
123
Azidothymidine
Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)
124
Lamivudine
Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)
125
Tenofovir
Antiviral; HIV 1 NTRTI (nucleotide reverse transcriptase inhibitor)
126
Nevirapine
Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)
127
Efavirenz
Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)
128
Delavirdine
Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)
129
-"navir" drugs
Antiviral HIV 3 PI (Protease inhibitor)
130
Nelfinavir
Antiviral HIV 3 PI (Protease inhibitor)
131
Bacitracin
antibacterial; polypeptide; inhibits cell wall synthesis
132
Polymyxin B
antibacterial; polypeptide; increases cell wall permeability
133
Metronidazole
antibacterial; disrupts DNA by inhibiting nucleic acid synthesis
134
Tinidazole
antibiotic
135
Nitrofurantion
antibiotic; inhibits DNA, RNA, Protein, and cell wall synthesis
136
Chloramphenicol
antibiotic; inhibits protein synthesis
137
Ritonavir
Antiviral HIV 3 PI (Protease inhibitor)
138
Saquinavir
Antiviral HIV 3 PI (Protease inhibitor)
139
Indinavir
Antiviral HIV 3 PI (Protease inhibitor)
140
Atazanavir
Antiviral HIV 3 PI (Protease inhibitor)
141
Daranavir
Antiviral HIV 3 PI (Protease inhibitor)
142
"gravir" drugs
Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)
143
Dolutegravir
Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)
144
Raltegravir
Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)
145
Cobicistat
Antiviral HIV 5 (other); antiretroviral booster
146
Enfuvirtide
Antiviral HIV 5 (other); entry blocker/fusion inhibitor
147
Interferon alfa 2b
Antiviral HBV and HCV (Hep B and C) drug
148
Peginterferon alfa 2a
Antiviral HBV and HCV (Hep B and C) drug
149
Lamivudine
Antiviral HBV (Hep B) drug
150
Ribavirin
Antiviral HCV (Hep C) drug
151
Peginterferon alfa 2b
Antiviral HBC (Hep C) drug
152
ledipasvir/sofosbavir
Antiviral HBC (Hep C) drug
153
Acyclovir
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
154
Famciclovir
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
155
Foscarnet
Antiviral HSV, VZV; (Herpes/Varicella/Zoster) ***and CMV***
156
Valacyclovir
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
157
Ganciclovir ophthalmic
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
158
Vidarabine
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
159
Idoxuridine
Antiviral HSV, VZV; (Herpes/Varicella/Zoster)
160
Ganciclovir
Antiviral HSV, VZV; (Herpes/Varicella/Zoster) **and CMV***
161
Amantadine
Antiviral Influenza
162
Rimatidine
Antiviral Influenza
163
Oseltamivir
Antiviral Influenza
164
Zanamivir
Antiviral Influenza
165
Atovaquone/proguanil
Antiparasitic; malaria
166
Chloroquine phosphate
Antiparasitic; malaria
167
Primaquine phosphate
Antiparasitic; malaria
168
Mefloquine
Antiparasitic; malaria
169
Pyrimethamine
Antiparasitic; Malaria Toxoplasmosis
170
Sulfadoxine/pyrimethamine
Antiparasitic; Malaria Toxoplasmosis
171
Suramin
Antiparasitic; trypanosomiasis
172
Melarsoprol
Antiparasitic; trypanosomiasis
173
Nifurtimox
Antiparasitic; trypanosomiasis
174
Metronidazole
Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis
175
Paramomycin
Antiparasitic; amebiasis
176
Metronidazole
Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis
177
Metronidazole
Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis
178
Pyrimethamine
Antiparasitic; Malaria Toxoplasmosis
179
Sulfadoxine
Antiparasitic; Malaria Toxoplasmosis
180
Permethrin topical
antiparasitic; scabies and lice
181
Crotamiton topical
antiparasitic; scabies
182
Lindane topical
antiparasitic; scabies
183
Permethrin topical
antiparasitic; scabies and lice
184
Ivermectin
antiparasitic and antihelminth; Roundworm/Hookworm/Pinworm and lice
185
Malathion toipcal
antiparasitic; lice
186
Albendazole
antihelminth; ***Roundworm/Hookworm/Pinworm and tapeworms***
187
Mebendazole
antihelminth; Roundworm/Hookworm/Pinworm
188
Pyrantel pamoate
antihelminth; Roundworm/Hookworm/Pinworm
189
Ivermectin
antiparasitic and antihelminth; Roundworm/Hookworm/Pinworm and lice
190
Piperazine
antihelminth; Roundworm/Hookworm/Pinworm
191
Niclosamide
antihelminth; tapeworms
192
Praziquantel
antihelminth; tapeworms
193
Albendazole
antihelminth; ***Roundworm/Hookworm/Pinworm and tapeworms***
194
Praziquantel
antihelminth; **tapeworms and flukes***