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Pharm 4 Flashcards

1
Q

beta-lactam antibiotic MOA

A

inhibits cell wall synthesis

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2
Q

-cillin

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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3
Q

Penicillin G

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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4
Q

Penicillin V

A

Penicillins; beta-lactam antibiotic; inhibitor of cell wall synthesis

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5
Q

Oxacillin

A

anti-staph penicillin; beta-lactam

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6
Q

Dicloxacillin

A

anti-staph penicillin; beta-lactam

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7
Q

Naficillin

A

anti-staph penicillin; beta-lactam

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8
Q

Ampicillin

A

broad spectrum penicillin; beta-lactam

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9
Q

Amoxicillin

A

broad spectrum penicillin; beta-lactam

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10
Q

Ticaricillin

A

anti-pseudomonal penicillin; beta-lactam

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11
Q

Piperacillin

A

anti-pseudomonal penicillin; beta-lactam

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12
Q

Clavulanic acid

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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13
Q

Sulbactam

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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14
Q

Tazobactam

A

Beta-lactamase inhibitor; used in combo with beta-lactam drug

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15
Q

Probenecid

A

blocks tubular transport increasing plasma penicillin levels; used in combo with beta-lactam drug

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16
Q

“cefs”

A

Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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17
Q

Cephalexin

A

1st gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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18
Q

Cefazolin

A

1st gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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19
Q

Cefaclor

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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20
Q

Cefuroxime axetil

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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21
Q

Cefuroxime sodium

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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22
Q

Cefoxitin

A

2nd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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23
Q

Cefiditoren pivoxil

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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24
Q

Cefidinir

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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25
Q

Ceftibuten

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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26
Q

Ceflixime

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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27
Q

Ceftriaxone

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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28
Q

Ceftazidime sodium

A

3rd gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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29
Q

Cefepime

A

4th gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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30
Q

Ceftaroline fosamil

A

5th gen Cephalosporin; beta-lactam antibiotic; inhibitor of cell wall synthesis

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31
Q

“penems”

A

Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis

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32
Q

Meropenem

A

Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis

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33
Q

Doripenem

A

Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis

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34
Q

Imipenem/Cilastatin

A

Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis; + inhibitor of renal dihydropeptidase 1 preventing penem degradation

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35
Q

Ertapenem

A

Carbapenems; beta-lactam antibiotic; inhibitor of cell wall synthesis

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36
Q

Cilastatin

A

inhibitor of renal dihydropeptidase 1 preventing penem degradation

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37
Q

Monobactam drugs

A

beta-lactam antibiotic; inhibitor of cell wall synthesis

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38
Q

Aztreonam

A

Monobactam; beta-lactam antibiotic; inhibitor of cell wall synthesis

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39
Q

Glycopeptide

A

beta-lactam antibiotic; inhibitor of cell wall synthesis and inhibits RNA synthesis

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40
Q

Vancomycin

A

Glycopeptide beta-lactam antibiotic; inhibitor of cell wall synthesis and inhibits RNA synthesis

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41
Q

Lipoglycopeptide

A

beta-lactam antibiotic; inhibitor of cell wall synthesis

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42
Q

Telavancin

A

Lipoglycopeptide; beta-lactam antibiotic; inhibitor of cell wall synthesis

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43
Q

Sulfonamides

A

Folic acid synthesis inhibitor; inhibits metabolism

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44
Q

Sulfamethoxazole/Trimethoprim

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism

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45
Q

Sulfisoxazole

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism

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46
Q

Sulfacetamide topical

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism

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47
Q

Sulfacetamide opthalmic

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism

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48
Q

Silver sulfadiazine

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits metabolism; used for burns

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49
Q

Trimethoprim

A

inhibits dihydrofolate reductase; this inhibits folic acid reduction

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50
Q

“floxacin” drugs

A

Quinolones; inhibits nucleic acid synthesis or function

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51
Q

Quinolone drugs

A

inhibits nucleic acid synthesis or function

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52
Q

Ciprofloxacin

A

Quinolone; inhibits nucleic acid synthesis or function

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53
Q

Levoflaxacin

A

Quinolone; inhibits nucleic acid synthesis or function

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54
Q

Moxifloxacin

A

Quinolone; inhibits nucleic acid synthesis or function

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55
Q

Gemfloxacin

A

Quinolone; inhibits nucleic acid synthesis or function

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56
Q

Ofloxacin

A

Quinolone; inhibits nucleic acid synthesis or function

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57
Q

Besifloaxacin opthalmic

A

Quinolone; inhibits nucleic acid synthesis or function

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58
Q

“sulfa” drugs

A

Sulfonamides; Folic acid synthesis inhibitor; inhibits

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59
Q

Rifamycins

A

inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis

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60
Q

“Rifa” drugs

A

Rifamycins; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis

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61
Q

Rifampin

A

Rifamycin; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis

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62
Q

“cycline drugs”

A

Tetracylcine or glycylcycline; inhibitors of protein synthesis

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63
Q

Tetracylcine drugs

A

inhibitors of protein synthesis

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64
Q

Doxycycline

A

Tetracycline; inhibitor of protein synthesis

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65
Q

Minocycline

A

Tetracycline; inhibitor of protein synthesis

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66
Q

Tetracycline

A

Tetracycline; inhibitor of protein synthesis

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67
Q

Tigecycline

A

Glycylcycline; inhibitor of protein synthesis

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68
Q

Aminogycoside drugs

A

Inhibitors of protein synthesis

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69
Q

Amikacin

A

Aminogycosides; Inhibitors of protein synthesis

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70
Q

Gentamicin

A

Aminogycosides; Inhibitors of protein synthesis

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71
Q

Neomycin

A

Aminogycosides; Inhibitors of protein synthesis

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72
Q

Paromomycin

A

Aminogycosides; Inhibitors of protein synthesis

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73
Q

Streptomycin

A

Aminogycosides; Inhibitors of protein synthesis

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74
Q

Tobramycin

A

Aminogycosides; Inhibitors of protein synthesis

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75
Q

Macrolide drugs

A

Inhibitors of protein synthesis

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76
Q

Azithromycin

A

Macrolide; Inhibitors of protein synthesis

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77
Q

Erythromycin

A

Macrolide; Inhibitors of protein synthesis

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78
Q

Clarithromycin

A

Macrolide; Inhibitors of protein synthesis

79
Q

Telithromycin

A

Ketolide drug (Macrolide); Inhibitors of protein synthesis

80
Q

Lincosamide drugs

A

Inhibitors of protein synthesis

81
Q

Clindamycin

A

Lincosamide; Inhibitor of protein synthesis

82
Q

Lincomycin

A

Lincosamide; Inhibitor of protein synthesis

83
Q

Streptogramin drugs

A

Inhibitor of protein synthesis

84
Q

Quinupristin/Dalfopristin (Synercid)

A

Streptogramin drug; inhibitor of protein synthesis

85
Q

Oxazolidinone drugs

A

Inhibitor of protein synthesis

86
Q

Linezolid

A

Oxazolidinone; Inhibitor of protein synthesis

87
Q

Mupirocin

A

binds to isoleucyl-tRNA synthetase, inhibiting protein synthesis

88
Q

Isoniazid

A

TB drug; inhibits mycolic acid synthesis, disrupting cell wall

89
Q

Rifampin

A

TB drug; inhibits DNA-dependent RNA polymerase; inhibiting mRNA synthesis

90
Q

Pyrazinamide

A

TB drug; inhibits mycobacterial growth

91
Q

Ethambutol

A

TB drug; inhibits metabolite synthesis

92
Q

Clarithrromycin

A

TB drug; Mycobacterium Avium Complex (MAC) drug; Macrolide; Inhibitors of protein synthesis

93
Q

Azithromycin

A

TB drug; Mycobacterium Avium Complex (MAC) drug; Macrolide; Inhibitors of protein synthesis

94
Q

Nystatin

A

Polyene antifungal; oral

95
Q

Amphotericin B

A

Polyene antifungal; IV

96
Q

Nystatin topical

A

Polyene antifungal; topical

97
Q

Azole drugs

A

Imidazole (most likely) or Triazole drug

98
Q

Ketoconazole

A

Imidazole antifungal; oral

99
Q

Micoconazole oropharyngeal

A

Imidazole antifungal; for oral candidiasis

100
Q

Clotrimazole

A

Imidazole antifungal; for oral candidiasis

101
Q

Butoconazole vaginal

A

Imidazole antifungal; vaginal

102
Q

Tioconazole vaginal

A

Imidazole antifungal; vaginal

103
Q

Clotrimazole topical

A

Imidazole antifungal; topical

104
Q

Econazole topical

A

Imidazole antifungal; topical

105
Q

Ketaconazole topical

A

Imidazole antifungal; topical

106
Q

Miconazole topcial

A

Imidazole antifungal; topical

107
Q

Itraconazole

A

Triazole antifungal

108
Q

Fluconazole

A

Triazole antifungal

109
Q

“fine” drugs

A

Allylamine antifungal

110
Q

Terbinafine

A

Allylamine antifungal; oral

111
Q

Butenafine topical

A

Allylamine antifungal; topical

112
Q

Naftifine topical

A

Allylamine antifungal; topical

113
Q

Terbinafine topical

A

Allylamine antifungal; topical

114
Q

“fungin” drugs

A

Echinocandin antifungal

115
Q

Andidulafungin

A

Echinocandin antifungal; IV

116
Q

Caspofungin

A

Echinocandin antifungal; IV

117
Q

Micafungin

A

Echinocandin antifungal; IV

118
Q

Flucytosine

A

antifungal; oral

119
Q

Griseofulvin

A

antifungal; oral

120
Q

Ciclopirox topical

A

antifungal; topical

121
Q

Tolnaflate topical

A

antifungal; topical

122
Q

Zidovudine

A

Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)

123
Q

Azidothymidine

A

Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)

124
Q

Lamivudine

A

Antiviral; HIV 1 NRTI (nucleoside reverse transcriptase inhibitor)

125
Q

Tenofovir

A

Antiviral; HIV 1 NTRTI (nucleotide reverse transcriptase inhibitor)

126
Q

Nevirapine

A

Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)

127
Q

Efavirenz

A

Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)

128
Q

Delavirdine

A

Antiviral; HIV 2 NNRTI (non-nucleoside reverse transcriptase inhibitor)

129
Q

-“navir” drugs

A

Antiviral HIV 3 PI (Protease inhibitor)

130
Q

Nelfinavir

A

Antiviral HIV 3 PI (Protease inhibitor)

131
Q

Bacitracin

A

antibacterial; polypeptide; inhibits cell wall synthesis

132
Q

Polymyxin B

A

antibacterial; polypeptide; increases cell wall permeability

133
Q

Metronidazole

A

antibacterial; disrupts DNA by inhibiting nucleic acid synthesis

134
Q

Tinidazole

A

antibiotic

135
Q

Nitrofurantion

A

antibiotic; inhibits DNA, RNA, Protein, and cell wall synthesis

136
Q

Chloramphenicol

A

antibiotic; inhibits protein synthesis

137
Q

Ritonavir

A

Antiviral HIV 3 PI (Protease inhibitor)

138
Q

Saquinavir

A

Antiviral HIV 3 PI (Protease inhibitor)

139
Q

Indinavir

A

Antiviral HIV 3 PI (Protease inhibitor)

140
Q

Atazanavir

A

Antiviral HIV 3 PI (Protease inhibitor)

141
Q

Daranavir

A

Antiviral HIV 3 PI (Protease inhibitor)

142
Q

“gravir” drugs

A

Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)

143
Q

Dolutegravir

A

Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)

144
Q

Raltegravir

A

Antiviral HIV 4 INSTI (integrase inhibitor; IN strand transfer inhibitor)

145
Q

Cobicistat

A

Antiviral HIV 5 (other); antiretroviral booster

146
Q

Enfuvirtide

A

Antiviral HIV 5 (other); entry blocker/fusion inhibitor

147
Q

Interferon alfa 2b

A

Antiviral HBV and HCV (Hep B and C) drug

148
Q

Peginterferon alfa 2a

A

Antiviral HBV and HCV (Hep B and C) drug

149
Q

Lamivudine

A

Antiviral HBV (Hep B) drug

150
Q

Ribavirin

A

Antiviral HCV (Hep C) drug

151
Q

Peginterferon alfa 2b

A

Antiviral HBC (Hep C) drug

152
Q

ledipasvir/sofosbavir

A

Antiviral HBC (Hep C) drug

153
Q

Acyclovir

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

154
Q

Famciclovir

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

155
Q

Foscarnet

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster) and CMV

156
Q

Valacyclovir

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

157
Q

Ganciclovir ophthalmic

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

158
Q

Vidarabine

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

159
Q

Idoxuridine

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster)

160
Q

Ganciclovir

A

Antiviral HSV, VZV; (Herpes/Varicella/Zoster) and CMV*

161
Q

Amantadine

A

Antiviral Influenza

162
Q

Rimatidine

A

Antiviral Influenza

163
Q

Oseltamivir

A

Antiviral Influenza

164
Q

Zanamivir

A

Antiviral Influenza

165
Q

Atovaquone/proguanil

A

Antiparasitic; malaria

166
Q

Chloroquine phosphate

A

Antiparasitic; malaria

167
Q

Primaquine phosphate

A

Antiparasitic; malaria

168
Q

Mefloquine

A

Antiparasitic; malaria

169
Q

Pyrimethamine

A

Antiparasitic; Malaria Toxoplasmosis

170
Q

Sulfadoxine/pyrimethamine

A

Antiparasitic; Malaria Toxoplasmosis

171
Q

Suramin

A

Antiparasitic; trypanosomiasis

172
Q

Melarsoprol

A

Antiparasitic; trypanosomiasis

173
Q

Nifurtimox

A

Antiparasitic; trypanosomiasis

174
Q

Metronidazole

A

Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis

175
Q

Paramomycin

A

Antiparasitic; amebiasis

176
Q

Metronidazole

A

Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis

177
Q

Metronidazole

A

Antiparasitic; amebiasis, Giardiasis, and Trichomoniasis

178
Q

Pyrimethamine

A

Antiparasitic; Malaria Toxoplasmosis

179
Q

Sulfadoxine

A

Antiparasitic; Malaria Toxoplasmosis

180
Q

Permethrin topical

A

antiparasitic; scabies and lice

181
Q

Crotamiton topical

A

antiparasitic; scabies

182
Q

Lindane topical

A

antiparasitic; scabies

183
Q

Permethrin topical

A

antiparasitic; scabies and lice

184
Q

Ivermectin

A

antiparasitic and antihelminth; Roundworm/Hookworm/Pinworm and lice

185
Q

Malathion toipcal

A

antiparasitic; lice

186
Q

Albendazole

A

antihelminth; Roundworm/Hookworm/Pinworm and tapeworms

187
Q

Mebendazole

A

antihelminth; Roundworm/Hookworm/Pinworm

188
Q

Pyrantel pamoate

A

antihelminth; Roundworm/Hookworm/Pinworm

189
Q

Ivermectin

A

antiparasitic and antihelminth; Roundworm/Hookworm/Pinworm and lice

190
Q

Piperazine

A

antihelminth; Roundworm/Hookworm/Pinworm

191
Q

Niclosamide

A

antihelminth; tapeworms

192
Q

Praziquantel

A

antihelminth; tapeworms

193
Q

Albendazole

A

antihelminth; Roundworm/Hookworm/Pinworm and tapeworms

194
Q

Praziquantel

A

antihelminth; tapeworms and flukes*

pharm (5 decks)

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