Pharm Effects And Clinical Use Of Adrenoceptor Agonists Flashcards
What is the pharmacological effect (and receptor) of direct acting catecholamine Dobutamine?
Cardiac stimulant (B1)
Vasodilation (B2)
What is the clinical use for Dobutamine?
Shock, AHF, and cardiac stimulation during surgery
What is the pharmacological effect (and receptor) of direct acting catecholamine Dopamine?
Cardiac stimulation (B1)
Increased BP (B1 / A1)
What is the clinical use of Dopamine?
Shock, HF, Hypotension
What is the pharmacological effect (and receptor) of direct acting catecholamine Epinephrine?
Vasoconstriction (a1)
Cardiac stimulation (B1)
Increased BP and Bronchodilation (B2)
What is the clinical use of Epinephrine?
Anaphylaxis, cardiac arrest, V fib, reduce bleeding, prolong affects of local anesthetics
What is the pharmacological effect (and receptor) of direct acting catecholamine Isoproterenol?
Cardiac stimulation (B1)
Bronchodilation (B2)
Wha this the clinical use of isoproterenol?
Atrioventricular block
Bradycardia
What is the pharmacological effect (and receptor) of direct acting catecholamine Norepinephrine?
Vasoconstriction and Increase BP (a1)
What is the clinical use of norepinephrine?
Hypotension and shock
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Albuterol?
Bronchodilation (B2)
What is the clinical use of Albuterol?
Asthma
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Brimonidine?
Decreased aqueous humor formation (a2)
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Apraclonidine?
Decreased aqueous humor formation (a2)
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Clonidine?
Decreased sympathetic outflow from CNS (a2)
What is the clinical use of Clonidine?
HTN
Opioid dependence
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Dexmetomidine?
Sedation (a2)
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Midodrine?
Vasoconstriction (a1)
What is the clinical use of midodrine?
Orthostatic hypotension
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Oxymetazoline?
Vasoconstriction (a1)
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Phenylphrine?
Vasoconstriction, increased BP and mydriasis (a1)
What is the pharmacological effect (and receptor) of direct acting non-catecholamine Terbutaline?
Bronchodilation (B2)
What is the pharmacological effect (and receptor) of indirect acting agent amphetamine?
Increase in NE release, and CNS stimulation
What is the pharmacological effect (and receptor) of indirect acting agent Cocaine?
Inhibition of NE uptake
