PHARM DRUG CLASSES Flashcards
What are ACE I?
ACE inhibitors reduce the activity of the renin-angiotensin-aldosterone system
thus reduce work of heart
What is suffix for ACE I?
-pril
What are examples?
captopril, enalpril, lisinopril
What are they used for?
anti HTN, CHF
General SE of ACE I?
hypotension, cough, hyperkalemia, headache, dizziness, fatigue, nausea, and renal impairment.
What are ARB?
Blockage of AT1 receptors directly causes vasodilation, reduces secretion of vasopressin, and reduces production and secretion of aldosterone
reducing BP
suffix for ARB?
-sartan
uses for ARB?
anti HTN, CHF
SE for ARB?
dizziness, headache, and/or hyperkalemia. orthostatic hypotension,
What are azole fungals?
inhibits cytochrome P450 fungal enzyme
used for fungal infections
What is -azole suffix?
azole
What are barbiturates?
are drugs that act as central nervous system depressants, from mild sedation to total anesthesia. and anti seizures
What is suffix?
-barbital
What are benzodiazepines?
enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant
What is suffix for benzo’s?
-epam or -olam
What are SE of benzo’s?
drowsiness, dizziness, and decreased alertness and concentration. Lack of coordination may result in falls and injuries, in particular, in the elderly.Decreased libido and erection Depression Hypotension and suppressed breathing (hypoventilation) may be encountered with intravenous use.
What are Beta blockers?
Beta blockers block the action of endogenous catecholamines epinephrine (adrenaline) and norepinephrine (noradrenaline) on adrenergic beta receptors, of the sympathetic nervous system, which mediates the fight-or-flight response.
What are BB used for?
angina, CHF, HTN, arrhytmias, CHF
What are SE of BB?
nausea, diarrhea, bronchospasm, dyspnea, exacerbation of Raynaud’s syndrome, bradycardia, hypotension, heart failure, heart block, fatigue, dizziness, alopecia (hair loss), , erectile dysfunction and/or alteration of glucose and lipid metabolism.
What are CCB?
are several medications that disrupt the movement of calcium (Ca2+
) through calcium channels
What are the two types of CCB?
- dihydropyridine- used to reduce systemic vascular resistance and arterial pressure
- non- di- relatively selective for myocardium, reduce myocardial oxygen demand and reverse coronary vasospasm
What are SE of CCB?
Dizziness, headache, redness in the face Fluid buildup in the legs and ankle edema Rapid heart rate Slow heart rate Constipation Gingival overgrowth
What are glucocorticoids?
anti inflammatory / immunosuppresive
What are examples of glucocorticoids?
cortisone, dexamethasone, prednisone