Pharm Ch 1 Flashcards
What are Aerosolized agents?
Group of aerosolized drugs that are instilled directly intro the trachea.
What are the categories of aerosolized drugs?
7 types
- adrenergic
- anti-cholenergic
- anti-asthmatic
- mucoactive
- corticosteroid
- anti-infective
- surfactant
What is airway resistance?
Measure of airway impedance
What is a brand name or trade name of a drug?
It’s a proprietary name given by the manufacturer.
Brand name and trade name are the same.
Chemical name?
Name derived form chemical structure.
COPD?
Chronic obstructive pulmonary disorder.
- airflow limitation that is not fully reversible and progressive.
- associated with abnormal inflammatory response of the lung.
Code name of a drug?
Name assigned by A manufacture to an experimental chemical that could be a new drug.
Drug administration?
Method by which a drug is made available to the body.
Generic name of a drug?
Name assigned to a chemical by U.S. Adopted name council when it shows to have therapeutic use and the drug company want to sell it.
Non-proprietary name of a drug?
Name of the drug other than it’s tradename.
Official name of the drug?
- after the drug is fully approved for use and entered into the national formulary.
- the drug’s generic name becomes official name.
Orphan drugs?
2 reasons of importance
Drug or biological products for the diagnosis or treatment of a rare disease
- affecting fewer than 200,000 people
- with no reasonable expectation of recovering cost of drug development but treats specific disease
Pharmacodynamics?
Dynamic is the drug on the body
dynamic DOB
Pharmacogenetics?
Study of the interrelationships between drugs and genetic differences
Pharmacokinetics?
Kinetic BOD
The effect of the body on the drugs
Pharmacology?
Study of drugs
Therapeutics?
Art of treating disease with drugs
What is phase 1 new drug approval?
Drug is administered and researched on a small group of a healthy volunteers
What is phase 2 new drug approval
Drug is investigated and administered to a small number of individuals with the disease
What is phase 3 new drug approval
Drug is administered to a large number of individuals with the disease. Multi center studies
What are over-the-counter drugs?
- drugs that have strength less than prescription formulation.
- yet still can have a hazardous affects if taken haphazardly
Why would you choose genetic over brand-name prescriptions?
- Cost associated with brand-name drug marketing.
- brand-name invested more money then generic brand name company
What are anti-infective agents
Antibiotics or antituberculosis drugs
What is an example of neuromuscular blocking agent?
Chariform agents
What is an example of CNS agents?
Analgesics and sedatives
What is an example of antiarrhythmic agents?
Cardiac glycosides and lidocaine
What are antihypertensive and Anti-anginal agents.
Beta blocking or nitroglycerin
What are examples of anticoagulant or Thrombolytic agents
Heparin or streptokinase
What are example of diuretics
Thiazides or furosemide
What are the purpose of beta adrenergic agents?
Relaxation the bronchial smooth muscle and bronchodilation.
- COPD
- asthma
- CF
- acute bronchitis
What are alpha-adrenergic agents used for?
-what do they treat?
Topical vasoconstriction and de-congestion
- treats upper airway swelling
What do anticholenergic agents do?
What do they treat?
Relaxation of cholinergic induced bronchoconstriction
-improve ventilation flow for COPD and asthma
What do mucoactive agents do?
2 points
- Changes properties of mucus in the airway.
- Reduces viscocity and promotion of clearance
What do corticosteroids treat?
Reduction in control of airway inflammation response associated with asthma or seasonal chronic rhinitis.
What are antiasthmatic agents used for?
Prevention of onset and development of asthmatic response through inhibition of airway inflammation
What are exogenous surfactants used for?
Normalizing lung compliance for newborns in distress.
Surface tension
What are prostacyclin analogues used for?
Treats pulmonary hypertension
-decreases shortness of breath and increasing walking distance
What is ARDS?
Respiratory insufficiency as a result of:
- trauma
- pneumonia
- O2 toxicity
- gram neg sepsis
- systemic inflammatory response
