Pharm Ch 1 Flashcards

1
Q

What are Aerosolized agents?

A

Group of aerosolized drugs that are instilled directly intro the trachea.

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2
Q

What are the categories of aerosolized drugs?

7 types

A
  • adrenergic
  • anti-cholenergic
  • anti-asthmatic
  • mucoactive
  • corticosteroid
  • anti-infective
  • surfactant
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3
Q

What is airway resistance?

A

Measure of airway impedance

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4
Q

What is a brand name or trade name of a drug?

A

It’s a proprietary name given by the manufacturer.

Brand name and trade name are the same.

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5
Q

Chemical name?

A

Name derived form chemical structure.

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6
Q

COPD?

A

Chronic obstructive pulmonary disorder.

  • airflow limitation that is not fully reversible and progressive.
  • associated with abnormal inflammatory response of the lung.
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7
Q

Code name of a drug?

A

Name assigned by A manufacture to an experimental chemical that could be a new drug.

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8
Q

Drug administration?

A

Method by which a drug is made available to the body.

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9
Q

Generic name of a drug?

A

Name assigned to a chemical by U.S. Adopted name council when it shows to have therapeutic use and the drug company want to sell it.

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10
Q

Non-proprietary name of a drug?

A

Name of the drug other than it’s tradename.

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11
Q

Official name of the drug?

A
  • after the drug is fully approved for use and entered into the national formulary.
  • the drug’s generic name becomes official name.
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12
Q

Orphan drugs?

2 reasons of importance

A

Drug or biological products for the diagnosis or treatment of a rare disease

  • affecting fewer than 200,000 people
  • with no reasonable expectation of recovering cost of drug development but treats specific disease
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13
Q

Pharmacodynamics?

A

Dynamic is the drug on the body

dynamic DOB

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14
Q

Pharmacogenetics?

A

Study of the interrelationships between drugs and genetic differences

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15
Q

Pharmacokinetics?

A

Kinetic BOD

The effect of the body on the drugs

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16
Q

Pharmacology?

A

Study of drugs

17
Q

Therapeutics?

A

Art of treating disease with drugs

18
Q

What is phase 1 new drug approval?

A

Drug is administered and researched on a small group of a healthy volunteers

19
Q

What is phase 2 new drug approval

A

Drug is investigated and administered to a small number of individuals with the disease

20
Q

What is phase 3 new drug approval

A

Drug is administered to a large number of individuals with the disease. Multi center studies

21
Q

What are over-the-counter drugs?

A
  • drugs that have strength less than prescription formulation.
  • yet still can have a hazardous affects if taken haphazardly
22
Q

Why would you choose genetic over brand-name prescriptions?

A
  • Cost associated with brand-name drug marketing.

- brand-name invested more money then generic brand name company

23
Q

What are anti-infective agents

A

Antibiotics or antituberculosis drugs

24
Q

What is an example of neuromuscular blocking agent?

A

Chariform agents

25
Q

What is an example of CNS agents?

A

Analgesics and sedatives

26
Q

What is an example of antiarrhythmic agents?

A

Cardiac glycosides and lidocaine

27
Q

What are antihypertensive and Anti-anginal agents.

A

Beta blocking or nitroglycerin

28
Q

What are examples of anticoagulant or Thrombolytic agents

A

Heparin or streptokinase

29
Q

What are example of diuretics

A

Thiazides or furosemide

30
Q

What are the purpose of beta adrenergic agents?

A

Relaxation the bronchial smooth muscle and bronchodilation.

  • COPD
  • asthma
  • CF
  • acute bronchitis
31
Q

What are alpha-adrenergic agents used for?

-what do they treat?

A

Topical vasoconstriction and de-congestion

- treats upper airway swelling

32
Q

What do anticholenergic agents do?

What do they treat?

A

Relaxation of cholinergic induced bronchoconstriction

-improve ventilation flow for COPD and asthma

33
Q

What do mucoactive agents do?

2 points

A
  • Changes properties of mucus in the airway.

- Reduces viscocity and promotion of clearance

34
Q

What do corticosteroids treat?

A

Reduction in control of airway inflammation response associated with asthma or seasonal chronic rhinitis.

35
Q

What are antiasthmatic agents used for?

A

Prevention of onset and development of asthmatic response through inhibition of airway inflammation

36
Q

What are exogenous surfactants used for?

A

Normalizing lung compliance for newborns in distress.

Surface tension

37
Q

What are prostacyclin analogues used for?

A

Treats pulmonary hypertension

-decreases shortness of breath and increasing walking distance

38
Q

What is ARDS?

A

Respiratory insufficiency as a result of:

  • trauma
  • pneumonia
  • O2 toxicity
  • gram neg sepsis
  • systemic inflammatory response