Chapter 8 - Xanthines Flashcards
What is other chemical has theophylline been compared to?
Caffeine
What class of drug is theophylline?
Bronchodilator
But a weak one
What is theophylline best used for?
To stimulate ventilatory drive and strengthen diaphragm
Who does theophylline treat?
Alternative treatment for Patients with a mild, persistent asthma older than 5.
Who are not recommended for theophylline?
Patients with acute asthma under the age of 5
What is the usage of theophylline for COPD patients?
It is not recommended for patients with exacerbated COPD.
There is not significant difference between beta agonists and anticholenergics over theophylline.
What can you use theophylline for with regards to babies?
Apnea of prematurity.
What do you use to create theophylline?
Alkaloid plants.
Like cocoa, tea leaves, kola nuts
What effects do the methylxanthine group cause in humans?
CNS stimulation Cardiac stimulation Diuresis Bronchial, uterine, and vascular smooth muscle Relaxation Coronary vasodilation Cerebral vasoconstriction
What side effects does theophylline cause?
Headache Anxiety Nausea Tachycardia Diuresis
What is the therapeutic range of theophylline?
5-20 micrograms per ml
What does smoking do to theophylline dose?
Inactivates it
When is it indicated to use theophylline?
When beta agonists and anticholenergics don’t fix underlying issue.
When is theophylline contraindicated?
Those with gastrointestinal issues
What does theophylline strengthen?
Respiratory muscle contractility
Respiratory muscle strength and endurance
