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Paige: Neuro! > Pharm blessings! > Flashcards

Pharm blessings! Flashcards

1
Q

If these cards look funny it’s because brainscape is taking away my ability to do cool things unless I pay money

A

anyway
time to have FUN and learn about neurological drugs
i mean neurololical
because lol

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2
Q

what is non-pharm sprain treatment

A

RICE
just eat a shit ton of rice
also Rest Ice Compression Elevation

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3
Q

what is a good pharm treatment for a sprain

A

scheduled vicoden for 1 week then NSAIDs

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4
Q

what is the primary goal with pain management?

A

increase functionality and normality for patient

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5
Q

is codeine a prodrug

A

yes they call it PROdeine

no they don’t

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6
Q

which drug can cause baby death because it’s excreted in the breast milk

A

codeine

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7
Q

what drugs have the most evidence in treating muscle spasms?

A

scheduled NSAIDs x 3days

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8
Q

what is the max ibuprofen dose per day

A

2400 mg

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9
Q

what is the max dose of naproxen [aleve]?

A

400mg/day

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10
Q

what muscle relaxant from msk can you give for a muscle spasm?

A

cyclobenzaprine

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11
Q

what are the 2 DOC for diabetic neuropathy?

A

duloxetine [cymbalta]

anitriptyline [elavil]

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12
Q

what drug class works best for diabetic neuropathy?

A

antidepressants

TCA, SNRI

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13
Q

will treating diabetic neuropathy cure all the pain

A

nope

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14
Q

what is the DOC for MS?

A

glatiramer acetate [copaxone]

but in a different case tdubs also said dimethyl fumarate [tecfidera] which is new soo

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15
Q

by how much does dimethyl fumerate [tecfidera] decrease MS relapses?

A

75%

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16
Q

by how much does glatiramer acetate [copaxone] reduce MS relapses?

A

28% / 35%

choose your own adventure / answer

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17
Q

what can you give for an acute MS attack

A

prednisone x 3d

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18
Q

your pt has chronic pain from OA with no response to vicoden so what do you do

A 
#1 drug test
#2 prescribe percocet
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19
Q

what is tolerance

A
  1. when you have a really annoying friend and you just put up with them
  2. when you used to be hammered off of 3 drinks but now you’re an alcoholic so 3 drinks don’t even touch you
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20
Q

what is dependence

A
  1. when that really annoying friend is super clingy

2. when you psychologically and physiologically need a drug to function

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21
Q

WHAT IS A SIDE EFFECT OF OPIOIDS

A

CONSTIPATION DAMN IT

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22
Q

your pt has severe pain from a hip fracture. what do you rx?

A

IV morphine

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23
Q

do you need to dose adjust morphine for CKD?

A

yes

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24
Q

what thing causes no pain when it hits you?

A

music

bob marley/sublime reference
(look up the song trenchtown rock)

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25
Q

which drug swears at you when you take it?

A

ibuprofane

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26
Q

these jokes are pathetic, i know

A

but not as pathetic as the lack of efficacy of codeine in 10% of the Caucasian population AM I RIGHT

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27
Q

what does codeine metabolize to

A

morphine

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28
Q

what is the biggest concern with IV opioids?

A

overdose leading to respiratory depression

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29
Q

what drug is an opioid antagonist

A

naloxone [narcan]

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30
Q

what opioid is 4x more potent than morphine?

A

hydromorphone [dilaudid]

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31
Q

what opioid is the MOST potent?

A

fentanyl [duragesic]

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32
Q

what should you do about a pre-surgical person’s metformin or glipizide while admitted?

A

d/c that and give insulin until 48hours after surgery

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33
Q

why can’t you give the elderly tramadol?

A

decreases seizure threshold

CNS symptoms

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34
Q

what 2 drugs did we prescribe in class for tonic-clonic seizures?

A

valproic acid [depakote]
carbamazepine
(you can give others, too)

35
Q

what seizure med can you use for all different types of seizures?

A

lamotrigine [lamictal]

36
Q

what is the DOC for petit mal seizures?

A

ethosuximide [zarontin]

37
Q

what do you give for status epilepticus?

A 
#1 IV lorazepam [ativan] for immediate seizing
#2 phenytoin [dilantin] in a different IV
38
Q

should you give phenytoin fast or slow, and why?

A

slow

can cause tissue necrosis otherwise

39
Q

what defines status epilepticus?

A

a tonic-clonic seizure lasting longer than 5 minutes

40
Q

do seizures meds have a wide or narrow therapeutic range?

A

narrow

41
Q

which anticonvulsant drug has a side effect of gingival hyperplasia?

A

phenytoin [dilantin]

42
Q

what supplement should you give with phenytoin [dilantin] (and maybe other seizure meds? idk)

A

folic acid

43
Q

what is a unique side effect of phenytoin [dilantin]

A

gingival hyperplasia like I just effing told you 2 cards ago

WORKIN’ THAT SHORT-TERM MEMORY BABY

44
Q

what drug is ACTUALLY FDA approved as an anticonvulsant, but has a crazy short half-life?

A

valium [diazepam]

45
Q

what is DOC for alzheimer’s disease?

A

donepezil [aricept]

46
Q

DEMENTIA TEST #1

you are in a race. you run past the person in 2nd place. what place are you in?

A

2nd

if you answered “first place,” start looking for a nursing home because you have dementia.

47
Q

what type of drug does donezapil [aricept] interact with?

A

anticholinergics

48
Q

what can you add to duloxetine [aricept] for alzheimer’s disease if it’s moderate to severe?

A

memantine [namenda]

49
Q

what drug class is memantine [namenda]?

A

NMDA receptor antagonist

50
Q

what imbalance causes seizures to happen?

A 
excess glutamate (excitatory)
less GABA (inhibitory)
51
Q

lorazepam [ativan] increases the neurotransmitter ______

A

GABA

52
Q

which anticonvulsant is most likely to cause the side effect of osteoporosis?

A

phenytoin [dilantin]

others do this, too

53
Q

What is the DOC for parkinson’s disease?

A

levodopa/carbidopa

54
Q

what dopamine agonist drug can you add to levodopa/carbidopa?

A

ropinorole [requip]

55
Q

what COMT inhibitor drug (which decreases dopamine degradation) can you add to levodopa/carbidopa?

A

Entacapone [comtan]

56
Q

DEMENTIA TEST #2
if a red house is made of red bricks, and a blue house is made of blue bricks, and a black house is made of black bricks, what is a green house made of?

A

you can’t grow wonderful gardens inside of a green brick building, dummy

greenhouses are made of glass

57
Q

how do you treat constipation with drugs

A

colace + senna

58
Q

how come some people don’t respond to codeine?

A

can’t metabolize CYP enzyme therefore can’t convert it to morphine

59
Q

WHAT OTC DRUG DECREASES THE EFFECTIVENESS OF ACE-I’S LIKE LISINOPRIL

A

NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS NSAIDS

60
Q

what is the “wearing off” phenomenon?

A

when drugs start to wear off after 5y of use

61
Q

what do you prescribe for MS muscle spasms?

A

the muscle relaxant Baclofen

62
Q

should you taper a patient off Baclofen

A

since this is even a flashcard, you better bet your sweet ass that the answer is yes

63
Q

with what neurological disorder can you not prescribe baclofen?

A

seizures

64
Q

does baclofen work in the CNS or PNS?

A

CNS

65
Q

Does dantrolene [dantrium] work in the CNS or PNS?

A

PNS

66
Q

what type of intolerance is a sign of MS?

A

heat intolerance

67
Q

are these pharm cards boring?

A

I’M SORRY BUT IT’S A BORING UNIT OKAY

68
Q

what do you call an epileptic in a pile of leaves?

A

Russell

69
Q

what should you prescribe for a migraine with aura?

A

elitriptan [relpax] or sumatriptan [imitrex] ASAP

70
Q

what can you rx for ppx of migraine?

how often must a person get migraines to get ppx treatment?

A

propanolol

must get migraines once per week

71
Q

what happens when you prescribe benzos for alzheimer’s disease?

A

the patients turn lime green

+ confusion + agitation

72
Q

what is the MC side effect of dimethyl fumerate [tecfidera]

A

flushing and GI side effects

73
Q

what can you do to counteract flushing?

A

take ASA 30 mins before med

like niacin

74
Q

what type of vaccines should you avoid with dimethyl fumerate [tecfidera]

A

live

75
Q

what pg category is dimethyl fumerate [tecfidera]?

A

PG-13

lol jk Cat C: avoid

76
Q

also shout out to bethany for making THE best pharm tables week after week

A

you da best

77
Q

what am I eating right now?

A

raspberries

just a fun fact about the author

78
Q

we are so close to the end and I’m stalling

A

these pesticides are giving me ADD

here we go here we go here we go

79
Q

if you prescribe fingolimod [gilenya] for MS, what tests should you order when you start it?

A

PFTs

and you monitor a shit ton of stuff

80
Q

if you’re on fingolimod [gilenya], how long do you have to wait before getting pregnant?

A

2 months

81
Q

what s/e are common for fingolimod [gilenya]?

A

man b00bs
^decide for yourself whether or not that’s true
HA, nausea, diarrhea

82
Q

what’s the rule for down-titrating morphine in the elderly

A

don’t
just keep it high and let them die

wow that was morbid
down titrate 5% every 2 weeks or something like that

83
Q

look we’re done in only 83 cards :)
see how quickly i can do this when i don’t dick around?
anyway, what time is it?

A

wine time.

good luck lovies!

Paige: Neuro! (7 decks)

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