Pharm

Question 1

acetaminophen MOA

Answer 1

decrease syn of prostaglandins

Question 2

NSAIDs

Answer 2

inhibit Cox I

Question 3

when to stop ASA before sx

other NSAIDs

Answer 3

1 week

3-5 days

Question 4

when should you avoid morphine

Answer 4

head trauma

Question 5

methadone

Answer 5

opioid agonist and NMDA antag

Question 6

beta lactams can induce this type of hypersensitivity

Answer 6

type I

Question 7

1st gen cephs

Answer 7

skin

Question 8

2nd gen cephs

Answer 8

Upper respiratory

PID

Question 9

3rd gen cephs

Answer 9

pneumonia + CNS

Question 10

vanco

Answer 10

red man syndrome, oto/nephro toxic

Question 11

tetacycline MOA

amingoglycosides

Answer 11

30s

Question 12

clinda MOA

macrolides

Answer 12

50s

good for PCN/ceph allergy

Question 13

FQ MOA

Answer 13

DNA gyrase

Question 14

Bactrim MOA

Answer 14

block folate

Question 15

what to monitor with INH

Answer 15

monitor LFTs, give B6, drug induced lupus

Question 16

furosemide

Answer 16

ascending loop of henle

Question 17

Non-dihydro

Answer 17

verapamil-affects contractility
diltiazem-angina/antiarythmias
SE constipation

Question 18

dihydro

Answer 18

amlodipine

vasodilation

Question 19

Digoxin

Answer 19

+ inotrope, used for HF/a-fib

Question 20

glitazones

Answer 20

BBW for MI

Question 21

what drug can be used to prevent tumor lysis syndrome

Answer 21

allopurinol

Question 22

carbamezapine SE

Answer 22

aplastic anemia, prevent Na influx

Question 23

phenytoin SE

Answer 23

gingival hyperplasia, osteoperosis, megaloblastic anemia

supplement with folate, Ca, Vit D

Question 24

what to monitor for valproate

Answer 24

LFT

Question 25

doxorubicin SE

Answer 25

cardiotoxicity

Question 26

Bleomycin

Answer 26

pulmonary fibrosis

Question 27

5-FU SE

Answer 27

mucositis

Question 28

cisplatin SE

Answer 28

peripheral neuropathy | ototoxicity

Question 29

cyclophosphamide SE

Answer 29

hemorrhagic cystitis

Question 30

adenosine and dipyramidole moa

Answer 30

vasodilation of coronary arteries

Question 31

Maoi can cause

Answer 31

HTN

Question 32

Tyrosine kinase inh are usedul for

Answer 32

CML

Question 33

Hydralazine is used in conj with

Answer 33

Isosorbide dinitritr

Question 34

HIV regimen

Answer 34

2 NRTIs + 1 other class

Question 35

argatroban

Answer 35

direct thrombin inhibitor

Question 36

clopidogrel

Answer 36

p2Y12 receptor inhibitor

Question 37

tamoxifen

Answer 37

``` prevent breast cancer lowers LDL increase bone density increases risk for endometrial/uterine cancer a/w increased risk of VTE ```

Question 38

what drugs effect warfarin

Answer 38

ketoconazole, INH, cimetidine

Question 39

drugs that cause dru induced lupus

Answer 39

procainamide, methyldopa, hydralazine

Question 40

this drug can cause depression, fatigue, insomnia, appetitie change

Answer 40

propranolol

Question 41

SE of heparin

Answer 41

osteoperosis | hyperkalemia

Question 42

thiazide diuretics can cause

Answer 42

hyponatremia

Question 43

tyramine MAO OD can lead to

Answer 43

HTN crisis

Question 44

best drug to treat hypertryglycerides

Answer 44

fibrates | however, they increase gallstone formation so use in caution w/GB disease

Question 45

lithium SE

Answer 45

hyperparathyroid, hypercalcemia, nephogenic DI, CKD, thyroid dysfunction, teratogenic

Question 46

drugs that cause QT prolongation

Answer 46

antipsychotics FQs macrolides

Question 47

HIT tx

Answer 47

switch to argatroban, fondaparinux

Question 48

digoxin SE

Answer 48

cardiac arrythmias confusion blurred vision/color elevated K

Question 49

hypokalemia typically occurs also with

Answer 49

hypomagnesia