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#GI II Test 2 > Pharm > Flashcards

Pharm Flashcards

1
Q

NS 3/4 drug names treats?

A

Gazoprevir/paritaprevir/simeprevir HCV -serine protease decreasee post tracrib procc/repli

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2
Q

NS5B names? treats?

A

Dasabuvir/Sofosbuvir HCV RNA polymerase decrease

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3
Q

NS5A Names? treats?

A

Elbasvir/Ledipasvir/Ombitasvir/Velpatasvir HCV decrease viral rep/assembly

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4
Q

Give to treat once daily with full coverage?

A

Velpatasvir/Sofosbuvir

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5
Q

NRTI the sides?

A

Lamivudine/telbivudine/entecavir

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6
Q

NRTI the tide?

A

Tenofovir/Adefovir

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7
Q

which NRTI is nephrotoxic? which is not?

A

TEnofovir. entecavir

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8
Q

Dont give IFN a to what patients?

A

Not compensated cirrhosis

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9
Q

IFN a will initially cause? MOA

A

initially cause increase in inflammation/fibrosis then decreases. MOA= JAK stat which increases ISGs which decrease replication

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#GI II Test 2 (8 decks)

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