Pharm Flashcards

1
Q

Antacid side effects

A
  • toxicity of Ca and Ma more likely in pt’s with renal disease
  • Combo products seek to balance constipating with laxative effects
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2
Q

magnesium salts

Milk of Magnesia

A

Saline laxative

draws water into the colon from surrounding tissue which stimulates contractions

use extensively for bowel prep

can be dangerous in pts with renal insufficiency

onset of action variable

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3
Q

Aluminum salts

Amphogel

A

Antacid

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4
Q

Magnesium & Calcium

Rolaids

A

Combo Antacid

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5
Q

sucralfate

Cytotec

A

Mucosal protectant

directly protects duodenal ulcers by forming barrier

no systematic effects

given before meals and at bedtime on an empty stomach

used as anti-ulcer agent in pts on LT NSAIDs and aspirin treatment

side effects

  • abdominal pain
  • diarrhea
  • spontaneous abortion
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6
Q

Hypertonic Solutions

A
  • D5LR
  • 3%NS
  • D5 1/2NS
  • D5NS
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7
Q

Ferrous Sulfate (Iron)

A
  • Necessary for production of hgb
  • Treats iron deficiency anemia
    (r/t chronic or acute blood loss, pregnancy, poor diet)

Mild anemia- increase dietary sources

Moderate anemia- PO/IM/IV supplementation

Severe anemia- transfusion

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8
Q

Hypotonic Solutions

A
  • 0.45% NaCl (1/2NS)
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9
Q

Magnesium & Aluminum

Maalox

A

Combo Antacid

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10
Q

Soapsuds enema

A

addition of castile soap

soap irritates intestines

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11
Q

Isotonic Solutions

A
  • 5% dextrose in H20 (D5W)
  • 0.9%NaCl (NS)
  • Lactated Ringer’s (LR)

Treat hypernatremia, replace water, used to administer medications

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12
Q

hydrochlorothiazide

Microzide

A

Thiazide diuretic

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13
Q

spironolactone

Aldactone

A

Potassium-sparing diuretic

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14
Q

Antiemetic Drugs

A

most effective when given in advance of event

most effective when combined to block different pathways

various routes utilized

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15
Q

senna/sennosides

Senokot

A

Stimulant Laxatives

bowel irritants- trigger peristatic contractions

harshest category, causes abdominal cramping

short-term use for acute constipation

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16
Q

Hypotonic enema

A

tap water

exerts pressure pefore escaping bowel into interstital space

17
Q

prochlorperazine

Compazine

A

Antidopaminergic Antiemetics

blocks dopamine receptors

antipsychotic and anticholinergic effects

frequently used for chemo and post-op

side effects

  • drowsiness
  • constipation
  • dry mouth/eyes
  • restlessness
  • blurred vision
  • disorientation
  • extrapyramidal effects (muscle issues)
18
Q

Isotonic enema

A

saline

stimulates peristalsis by presence

19
Q

Folic Acid (Folate)

A
  • preggers need double the dose

- Deficiency caused by dietary deficits, GI diseases, chemo, malignancy, cirrhosis

20
Q

Cleansing enema

A

any type that promotes complete bowel evcuation

21
Q

Vit b12 (Cyanocobalamin)

A
  • deficiency usually caused by poor or absent absorption (gastric resection, Crhon’s, pernicious anemia)
  • Dietary: meats, seafood eggs
  • Pernicious anemia, lacking intrisic factor/protein, need parental administration
22
Q

Sodium Salts

Alka-seltzer

A

Antacid

23
Q

Nursing Implications for Ferrous Sulfate

A
  • causes constipation
  • causes dark green or black stool
  • calcium inhibits absorption
  • Vit C enhances absorption
  • Best absorbed on empty stomach
  • Liquid needs to be dilute and drink through straw
  • use Z track for IM and monitor for phlebitis
24
Q

meclizine

Antivert

A

Antihistamine antiemetic

blacks h1 receptors in inner ear (motion sickness)

Side effects

  • sedation
  • dizziness
  • dry mouth
25
Q

glycerin suppositories

MiraLax, GoLytley

A

Hypersomotic laxative

draw water into colon from surrounding tissues which stimulates contractions

used for colon prep prior to diagnostic procedures

onset variable

26
Q
docusate sodium
(Colace)
A

emollient laxatives (stool softeners, surfactant laxatives )

enable mositure and fat to penetrate the stool, make it easier to pass

increased mass of stool stimulates peristalsis

widely used preventaively

27
Q

psyllium

Metamucil

A

Bulk forming laxatives

high in fiber which attracts fluid into colon

treat chronic constipation

gentle action, slow onset

danger of obstruction if fluid intake inadequate

28
Q

Calcium Salts

TUMS

A

Antacid

29
Q

Antacids

A
  • Neutralize stomach acid, provide only symptom relief
  • long term use can cause electrolyte imbalances
  • Most effective take 1-2 hours after eating and at bedtime
  • Liquids coat esophagus and stomach
  • Chewables need to be fully chewed and chased with water
  • May interfere with absorption of other drugs, do not take other meds within 1-2 hrs
  • cause premature release of enteric coated drugs
30
Q

metoclopramide

Reglan

A

Prokinetic Antiemtics

Stimulates forward peristalsis in GI tract (also blocks dopamine receptors)

side effects

  • drowsiness
  • extrapyramidal rxns
  • restlessness
31
Q

Famotidine

Pepcid

A

H2 receptor antagonist
(all “-tidine” drugs)

supresses secretion of gastric acid

once daily doses most effective if taken at bedtime

Multi-day dose taken after meals and at bedtime

Avoid antacids- interfere with absorption

Smoking decreases effectiveness

32
Q

ondansetron

Zofran

A

Serotonin antagonist antiemetic

selectively blocks specific serotonin receptors in GI tract, chemoreceptor trigger zone and medullary vomiting center

side effects (minimal)

  • headache
  • dizziness
  • diarrhea/constipation
33
Q

furosemide

Lasik

A

Loop diuretic

34
Q

Hypertonic enema

A

fleet, small volume

draws fluid into colon

35
Q

omeprazole

Prilosec

A

Proton Pump Inhibitor
(all “-prazole” drugs)

Totally blocks acid secretions

Stronger and longer lasting that h2 receptor antagonists

Drug of choice for gastric and duodenal ulcer treatment

long-term therapy associated with osteoporosis

most effective taken before first meal of day

can use antacid concurrently (Ca advised for LT therapy)

Avoid alcohol, antacids, irritating foods

36
Q

Magnesium Salts

Milk of Magnesia

A

Antacid and Laxative

37
Q

oil retention enema

A

lubricates rectum, colon and stool

penetrates stool to increase bulk and soften