Pharm- 7

Question 0

What is a conductor?

Answer 0

an object or type of material which permits the flow of electric charges in one or more directions

Question 1

What is a capacitor?

Answer 1

a passive two-terminal electrical component used to store energy in an electric field.

Question 2

What acts as a capacitor in the cell?

Answer 2

The lipid bilayer

Question 3

What are the things in the lipid bilayer that act as a conductor for electrical charges?

Answer 3

ion channels

Question 4

What are the 3 things to help make the resting membrane potential?

Answer 4

1. An unequal disruption of positive and negative charges on each side of the plasma membrane
2. A difference in selective permeabilities of the membrane to the various cations and anions
3. The current generating action of active energy and passive pumps that help maintain ion gradients

Question 5

Is there a higher concentration of K inside or outside of the cell?

Answer 5

Inside

Question 6

What causes K to flow out of the cell, if passive K channels are open?

Answer 6

concentration gradient

Question 7

What happens to the change in charge if K moves with the chemical gradient outside the cell?

Answer 7

The negative proteins (A-) are left inside, so the inside of the cell becomes more negative relative to the outside.

Question 8

Why does K eventually stop flowing outside of the cell, even thoguh there is still a chemical gradient for it to leave?

Answer 8

The pull of the electrical negativity inside the cell overcomes the chemical gradient. this is the electrochemical gradient.

Question 9

Which structures maintain the chemical concentrations of Na and K in and out of the cell?

Answer 9

Na/K ATPase pumps

Question 10

How many Na’s and K’s are pumped out/in of the cell via the Na/K ATPase pump?

Answer 10

3 Na’s out, 2 K’s in

Question 11

How many Ca’s and Na’s are pumped out/in of the cell via the Na/Ca exchanger?

Answer 11

1 Ca++ out, 3 Na+ in

Question 12

Which ion has the most effect on the Nerst eqn for cells?

Answer 12

K

Question 13

What is the Nerst eqn used for?

Answer 13

used to calculate the equilibrium potential at a given concentration differences of a SINGLE permeable ion across a cell membrane. It tells us what potential would exactly balance the tendency for diffusion down the concentration gradient

Question 14

What is the goldman eqn used for?

Answer 14

when resting potential is determined by TWO or MORE species of ions, the influence of each species is governed by its concentration inside and outside the cell and by the relative permeability of the membrane to that ion

Question 15

I’m not making cards on action potentials.

Answer 15

because there will be plenty of cards as it is. Want to hear a funny story?

I once saw chuck norris in hollywood. i told him he’s a big vagina and i made fun of his beard. i ran away quick knowing he couldnt catch me and hed never find s gjrgsrongosnr srvi44vsvrsrvonsboebnbnbnnbbonkeotebppsw[22’

Question 16

What does tetrodoxin do?

Answer 16

Blocks voltage-gated Na channels –> no AP –> fatal paralysis

Question 17

How is Ach degraded?

Answer 17

by acetylcholinsesterase in the synapse

Question 18

Drugs that block AchE are a good way to treat which disorder?

Answer 18

myasthenia gravis

Question 19

What does cocaine inhibit?

Answer 19

A BAD TIME YEEEEEEEEEEEEEE

also dopamine and NE reuptake in the brain

Question 20

what does fluoxetine inhibit?

Answer 20

serotonin reuptake (its an SSRI)