Pharm Flashcards
Reverse toxicity of Acetaminophen
N-acetylcysteine (replenishes glutathione)
Reverse toxicity of AChE inhibitors, organophosphates
Atropine > pralidoxime
Reverse toxicity of Antimuscarinic, anticholinergic agents
Physostigmine, control hyperthermia
Reverse toxicity of Arsenic
Dimercaprol, succimer
Reverse toxicity of Benzodiazepines
Flumazenil
Reverse toxicity of β-blockers
Atropine, glucagon
Reverse toxicity of Carbon monoxide
100% O2, hyperbaric O2
Reverse toxicity of Copper
Penicillamine, trientine (Copper penny)
Reverse toxicity of Cyanide
Nitrite + thiosulfate, hydroxocobalamin
Reverse toxicity of Digitalis (digoxin)
Anti-dig Fab fragments
Reverse toxicity of Heparin
Protamine sulfate
Reverse toxicity of Iron
Deferoxamine, deferasirox, deferiprone
Reverse toxicity of Mercury
Dimercaprol, succimer
Reverse toxicity of Methanol, ethylene glycol (antifreeze)
Fomepizole > ethanol, dialysis
Reverse toxicity of Methemoglobin
Methylene blue, vitamin C
Reverse toxicity of Opioids
Naloxone
Reverse toxicity of Salicylates
NaHCO3 (alkalinize urine), dialysis
Reverse toxicity of TCAs
NaHCO3
Reverse toxicity of Warfarin
Vitamin K (delayed effect), fresh frozen plasma (immediate)
How many 1/2 lives to reach steady state in first order kinetics?
4-5