PHARM

Question 1

How might an oral vs transdermal estrogen medicine be metabolized differently?

Answer 1

They wont be.

Question 2

What is the advice from the FDA on their Black Box warning regarding estrogen therapy for postmenopausal women?

Answer 2

Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals.

Question 3

A young woman presents to your clinic at age 5 for precocious puberty. what transdermal cream could be responsible for this?

Answer 3

Evamist skin applied hormone

Question 4

Name two combination estrogen and progesterone drugs

Answer 4

Prempro and femhrt

Question 5

Name 3 oral tablet progestin pills

Answer 5

Medroxyprogesterone acetate
Norethindrone
Prometrium

Question 6

Megestrol is what type of drug? What’s it’s theraputic use ?

Answer 6

synthetic progestin (works the same as progesterone) 
used for treating cachexia and cancer

Question 7

You patient is post menopausal and has been experiencing dyspareunia what do you recommend?

Answer 7

Either a topical low dose estrogen cream for the vagina w/o progesterone, or Ospemifene and estrogen receptor agonist on the endometrium

Question 8

What’s a new estrogen drug (not combo) that reduces the risk of endometrial hyperplasia; the major concern for those taking estrogen therapy alone?

Answer 8

conjugated estrogens + benzodoxifene the latter acts as a antagonist in the uterus but an agonist

Question 9

What is paroxetine used for?

Answer 9

SSRI used to treat symptoms of menopause

Question 10

Premarin is what?

Answer 10

pregnant mares urine a natural source of estrogen

Question 11

When is it recommended to use bio identical hormones?

Answer 11

With allergies to gov approved hormones. There are some risks with custom preparation of the BIH.

Question 12

Etodolac is contraindicated

Answer 12

with aspirin allergy

Question 13

What is the aspirin triad?

Answer 13

Aspirin allergy , asthma, Nasal polyps