Pharm 3 Final exam Flashcards
1
Q
Hydrocortisone
A
Corticosteroid, tx primary adrenocortical insufficiency (Addisons). Also 2ary 3ary, Identical to cortisone
2
Q
Indomethacin
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
3
Q
Ketorolac (Acular, Acuvail, Toradol)
A
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
4
Q
Metoclopramide (Reglan)
A
Blocks DA receptor to prevent chemo nausea. AE: sedation, diarrhea, extrapyramidal symptoms
5
Q
Etodolac
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
6
Q
Droperidol
A
Blocks DA receptors. Tx chemo nausea
7
Q
Norethindrone
A
Progestogens. Daily Progestin-only pill for contraceptive. MORE STABLE to first pass metabolism. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
8
Q
Formoterol
A
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
9
Q
Flutamide
A
Antiandrogens Tx prostatic carcinoma
10
Q
Glyburide
A
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
11
Q
Fludrocortisone
A
Mineralcorticoid, tx primary adrenocortical insufficiency
12
Q
Glipizide
A
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
13
Q
Haloperidol (Haldol)
A
Blocks DA receptors. Tx chemo nausea
14
Q
vasopressin / ADH
A
Posterior pituitary, not oral, tx diabetes insipidus
15
Q
Dextromethorphan
A
Morphine derivative. Tx cough, low addictive profile (but still possible), equally effective like codeine
16
Q
Repaglinide
A
Meglitinide, Stimulates beta cells to make insulin. 3 hour duration. Good for irregular meals. AE: weight gain
17
Q
Budesonide
A
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if “spacer” is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
18
Q
Sulindac
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
19
Q
Aprepitant
A
Substance P blocker. Tx chemo nausea. Targets neurokinin receptor in brain
20
Q
Psyllium (Metamucil)
A
Bulk laxative. Water retetion increases GI movement
21
Q
Propylthiouracil
A
Inhibits thyroid hormone synthesis, tx hyperthyroidism, short half life
22
Q
Sodium bicarbonate
A
Antacid. Tx peptic ulcer symptoms. AE systemic alkalosis
23
Q
Medroxyprogesterone
A
Progestogens. INJECTIBLE. MORE STABLE to first pass metabolism. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
24
Q
Prednisone
A
Corticosteroid
25
Diclofenac (Voltaren)
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
26
Methylcellulose (Citrucel)
Bulk laxative. Water retetion increases GI movement
27
Meloxicam
(NSAID)Oxicam Derivatives - long half lives.COX 2 selective at low doses
28
Latanoprost (Xalatan)
PFG analog. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increase iris pigmentation, eyelashes, and normally causes redeye
29
gold salts
DMARD. Suppresses phagocytosis of macrophages, delayed effect, has serious AE
30
Rabeprazole
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
31
Norelgestromin
Progestogens. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
32
Aluminum hydroxide
Antacid and antidiarrheal. Absorbs toxins, coats intestinal mucosa.
ALSO bulk laxative (simlar laxative ability as bran, seeds, methylcellulose)
33
Drospirenone With ethinyl estradiol (YAZ)
Progestogens, can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
34
Flunisolide
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
35
Lansoprazole (Prevacid)
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
36
Amoxicillin
Aminopenicillin, beta-lactam abx, prevents elongation of peptioglycans. Part of triple therapy against H. Pylori peptic ulcers.
37
Acarbose
α-Glucosidase Inhibitors(for DB) to prevent upper GI carb digestion to decrease postprandial release of glucose. Taken just before meals. AE: flatulence, GI problems (avoid if have IBD)
38
What drugs can increase iris pigmentation and increased eyelashes?
Latanoprost Travaprost Bimatoprost
39
Lactulose
Osmotic laxative holds water
40
Ciclesonide
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
41
Ketoprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
42
Zafirlukast
Leukotriene antagonist. Blocks effects of leuk. Tx asthma
43
Clarithromycin
Part of triple therapy against H. Pylori peptic ulcers.
44
Methimazole
Inhibits thyroid hormone synthesis, tx hyperthyroidism, short half life
45
Magnesium citrate
Osmotic laxative holds water
46
Cetirizine (Zyrtec)
H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation). Tx motion sickness
47
Indacaterol
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
48
Metronidazole
Part of triple or quadruple therapy against H. Pylori peptic ulcers.
49
Methylcellulose (Citrucel)
Bulk laxative increases water retention in GI tract
50
Leflunomide
DMARD.Decreases pyrimidine synthesis in lymphocytes. Ci pregnancy
51
Guaifenesin
Unknown MOA. Cough expectorant (bonus: reduces cough)
52
Which corticosteroid is preferred in pregnancy?
Prednisolone
53
What is the precursor of prostaglandins?
Arachidonic acid
54
Adalimumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
55
Empagliflozin
Na-Glu Cotransporter 2 inhibitor. Helps higher urination of glucose. AE: UTIs, urinary frequency, hypotension
56
Dutasteride
Antiandrogens Tx BPH
57
Bimatoprost (Lumigan, Latisse)
Prostaglandin analog. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increase iris pigmentation, eyelashes, and normally causes redeye
58
Rosiglitazone
Thiazolidinedione. Improves whole-body insulin sensitivity. Combination with insulin can increase heart failure risk.
59
Fluticasone (Flovent)
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
60
What's a common treatment for COPD?
-tropium (muscarnic blocker) and -erol (beta 2 agonist)
61
Why taper steroids?
So the low ACTH leves can gradually increase and return to normal
62
Oxaprozin
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
63
Oral contracepts vs Hormone therapy levels?
Dose is less in HT than contraception
64
Esomeprazole (Nexium)
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
65
Acetaminophen (Tylenol)
SUBSTITIUTE for nsaid. Prostaglandin synthesis inhibitor in CNS. Weak anti-inflammatory, does not affect platelet function. Tx viral infections in children. Hepatic necrosis at high doses
66
Diphenoxylate + atropine
Opioid-like effect on GI to slow GI tract. Tx Diarrhea
67
liothyronine
T3 substitute in hypothyroidism (long half-life)
68
thyroid stimulating hormone
Made by anterior pituitary, causes uptake of iodine and T4 T3 synthesis. Inducing P450 system accelarates metablism of thyroid hormones
69
Senna
Stimulant laxative
70
human menopausal gonadotropin
Gonadotropin, treat infertility
71
Certolizumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
72
Metformin
- increases liver sensitivity to insulin, inc skeletal muscle glucose uptake, renal cleared, dec hepatic glucose production. Avoid with alcohol abuse. Common GI distress
- drug of choice for newly diagnosed type 2DB
73
What drug is the "morning-after pill"?
High dose estrogen plus progestin
74
Omalizumab
Binds to IgE, tx asthma. Costly
75
Illoprost
Prostacyclin analog to increase cAMP, given via inhilation
76
pred forte
Corticosteroid
77
Exenatide
Glucagon-Like Polypeptide-1 Agonists. Helps suppress glucagon and enhances glucose-mediated insulin secretion. Injection only
78
Cromolyn
Mast cell stabilizer. Tx asthma, allergies. Prevention, not intervention for both diseases! Needs frequent dosing
79
Ranitidine (Zantac)
H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Longer acting, similar to Famotidine, more potant
80
What can be used orally for prostate cancer?
Bicalutamideand Nilutamide (Flutamine not oral)
81
Prolactin
Lactation, decreases reproductive function
82
What is ci for NSAIDS?
Post-op pain of coronary artery bypass graft.
83
Sucralfate
Mucosal protective agent. DON'T give with things that reduce acid (PPIs, H2 blockers, antacids)
84
Magnesium hydroxide
Antacid. And Osmotic laxative that holds water
85
What does the Middle zonafasciculata produce?
Glucocorticoids (invovled in metabolism and stress)
86
Mometasone
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
87
Naproxen (Aleve)
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
88
Travaprost (Travatan Z)
Prostaglandin pro-drug. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increase iris pigmentation, eyelashes, and normally causes redeye
89
What is the treatment escalation of type 2 diabetes?
Start with lifestyle and metformin. Then add sulfonyurea or insulin ThenThiazolidinedione or GLP-1 receptor agonist.
90
Triamcinolone (Kenalog)
Corticosteroid
91
Methylprednisolone (Medrol)
Corticosteroid. Tx inflammation
| Tx chemo nausea
92
Nilutamide
Antiandrogens. Oral treatment of prostate cancer
93
Methotrexate
DMARD. Immunosuppresant
94
Liraglutide
Glucagon-Like Polypeptide-1 Agonists. Helps suppress glucagon and enhances glucose-mediated insulin secretion. Injection only. CI family history of cancer
95
Eplerenone (Inspra)
k-sparing diuretic, aldosterone blocker
96
Prednisolone
Corticosteroid. Preferred in pregnancy
97
Aspirin
NSAID Irreversibly inactivates cyclooxygenase. Only lowers fevers, not normal body temps. Increase ventilation, less intestinal protective mucus, lower thromboxin production (less platelet aggregation). CAN CAUSE RAYE SYNDROME. 1st or 0 order elimination kidney extrected
98
Megestrol
Progestogens MORE STABLE to first pass metabolism. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
99
Pramlintide
Amylin analog. Delays gastic emtying to reduce needed insulin dose and improves satiety. Injected.
100
Which progestins are more stable?
Medroxyprogesterone, Megestrol, Norethindrone
101
Cox-1 or Cox-2 inhibition has fewer side effects?
Cox 2
102
Finasteride
Antiandrogens Tx BPH
103
Fenoprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
104
Cortisone
Corticosteroid
105
Palonosetron
5-HT3 blocker. Tx chemo nausea.
106
Benzonatate
Local anesthetic for respiratory passage to reduce cough reflex
107
Mifepristone
Progesterone antagonist. 1st trimester abortion
108
Pirbuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
109
Pantoprazole
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
110
Tolmetin
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
111
Progesterone
Progestogens. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
112
Granisetron
5-HT3 blocker. Tx chemo nausea.
113
Golimumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
114
Nabumetone
NSAID. Low AE
115
Tamoxifen
Selective Estrogen-Receptor Modulator (SERM), tx breast cancer. P450 metabolized, bile excreted
116
Docusate
Stool softener (constipation prevention)
117
Piroxicam
(NSAID)Oxicam Derivatives - long half lives
118
Celecoxib (Celebrex)
NSAID, more COX-2 selective for better pain management. Does not affect blood, but has other NSAID AE
119
How are Glucocorticoids and DMARDS implemented in disease therapy?
Glucocorticoids are used in rheumatoid arthritis until DMARDs kick in.
120
Chloroquine
DMARD
121
Levothyroxine
Tx hypothyroidism and thyroid replacement (long-half-life), T4 substitute
122
Tetracycline
Part of quadruple therapy against H. tx Pylori peptic ulcers.
123
Glycerin
suppositorie
124
Saxagliptin
Dipeptidyl Peptidase-IV Inhibitors. Use with diet and exercise
125
When should you not use an ocular steroid?
Do NOT use a (cortico)steroid for Herpes simplex EPITHELIAL keratitis
Also avoid for large corneal epithelial defects
126
What drug is nearly 100% bioavailable
Nizatidine (H2 blocker) has no liver metabolism
127
Codeine
Opiate. Gold standard for cough suppression. Decreases mucosal secretion
128
Ondansetron
5-HT3 blocker. Tx chemo nausea.
129
Theophylline
Increases cAMP for tx chronic asthma, drug is phased out because narrow TI. AE: Fatal arrhythmias
130
follicle-stimulating hormone
Gonadotropin, treat infertility
131
Beclomethasone
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
132
Raloxifene
Selective Estrogen-Receptor Modulator (SERM), bile excreted
133
Dolasetron
5-HT3 blocker. Tx chemo nausea.
134
Miglitol
α-Glucosidase Inhibitors(for DB) to prevent upper GI carb digestion to decrease postprandial release of glucose. Taken just before meals. AE: flatulence, GI problems (avoid if have IBD)
135
Diphenhydramine (Benadryl)
H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
136
Misoprostol
Prostaglandin E analog. Tx NSAID ulcers. Ci pregnancy
137
Misoprostol
PGE1 analog on parietal cells protects mucosal lining of stomach from NSAIDs. Can induce labor (and abortion)
138
Corticotropin
ACTH is made by anterior pituitary. Drug is a diagnostic tool for adrenal insufficiency
139
What does the Inner zonareticularis produce?
Androgens
140
Lubiprostone
Laxative. Acivates Cl channel to increase fluid secretion into intestine. NO POTENTIAL FOR DEPENDANCY. Tx: chronic constipation. AE: nausea
141
What can androgens treat?
Low testosterone males, osteoporosis and wasting from HIV/cancer severe burn healing Endometriosis
142
Meclofenamate
(NSAID) Fenamate. Severe side effects
143
Calcium carbonate (Tums)
Antacid. Tx peptic ulcer symptoms
144
Somatostatin
suppress GH and TSH, tx tumors
145
Somatotropin
Synthetic GH
146
Linagliptin
DPP-4 inhibitor, inc insulin dec glucagon
147
Loratadine (Claritin)
H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
148
Salmeterol
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
149
Prochlorperazine (Compazine)
Block DA receptors. Tx chemo nausea. AE: hypotension, restlessness, extrapyramidal symptoms
150
Montelukast (Singulair)
Leukotriene antagonist. Tx asthma and allergic rhinitis
151
Loperamide (Imodium A-D)
Opioid-like effect on GI to slow GI tract. Tx Diarrhea
152
Etanercept
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
153
Levalbuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
154
Estrogens has what AE?
Increase cervical cancer risk but lowers endometrial and ovarian cancer risk. weight gain. eEnchances serum lipids
155
Nateglinide
Meglitinide, Stimulates beta cells to make insulin. 3 hour duration. Good for irregular meals. AE: weight gain
156
Betamethasone
Corticosteroid. Fetal lung maturation before birth
157
Levonorgestrel
Progestogens. can cause acne, HA, depression, weightgain. Tx hormonal deficiency, contraception (in combination),
158
D-penicillamine
DMARD. Cysteine analog thatSlows progression of bone destruction and RA. Short-term tx only. Don't combine with other DMARDs
159
Flurbiprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
160
What are the side effects of corticosteroids?
Decreased growth in children, glaucoma, central fat, osteoporosis, infection risk, hair growth, increased appetite, peptic ulcer, hypertension, edema, hypokalemia, POSTERIOR SUBCAPSILAR CATARACT
161
Estriol
Metabolite of estradiol, Produced by the placenta
162
Gonadorelin
Posterior pituitary hormone.
| synthetic GnRH, tx prostate cancer, endometriosis, precocious puberty
163
Tobradex
Corticosteroid
164
Tiotropium (Spiriva)
Muscarinic blocker. Tx athsma (inhaled) (and helps COPD). Not as good as Beta 2 agonist for asthma.
Tx motion sickness
165
Spironolactone (Aldactone)
k-sparing diuretic, aldosterone blocker
166
What does the Outer zonaglomerulosa produce?
Mineralocorticoids (aldosterone)
167
Anakinra
Interleukin-1 receptor antagonist. Daily subcutaneous injection. Don't combine with TNF inhibitors
168
Nizatidine
H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Nearly 100% bioavailable
169
Albuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
170
Ketoconazole
Antifungal that Strongly inhibits all gonadaland adrenal steroid hormone synthesis, tx cushings
171
Alprazolam (Xanax)
Benzodiazepine. Tx anticipatory nausea
172
Infliximab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
173
Zileuton
Leukotriene antagonist. Prevents leuk. Formation. Tx asthma
174
Famotidine (Pepcid)
H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Similar to ranitidine, most potant.
175
human chorionic gonadotropin
Gonadotropin, treat infertility
176
Estrone
Metabolite of estrodial,Primary circulating estrogen after menopause
177
Ipratropium (Atrovent)
Muscarinic blocker. Tx athsma (inhaled) (and helps COPD). Not as good as Beta 2 agonist for asthma. Tx motion sickness
178
Which progestin can be a daily contraceptive?
Norethindrone
179
What can treat BPH?
Finasteride and dutasteride
180
Omeprazole (Prilosec)
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs. UNIQUE: can interfere with warfarin metabolism
181
Bicalutamide
Antiandrogens. Oral treatment of prostate cancer
182
Fexofenadine (Allegra)
H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
183
Which progestin is injectible?
Medroxyprogesterone
184
Glimepiride
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
185
What are testosterone AE?
Female masculinization
Males: Impotence, decreased spermatogenesis, gynecomastia, prostate growth
Lowers HDL and raises LDL :(
186
Pioglitazone
Thiazolidinedione. Improves whole-body insulin sensitivity. Combination with insulin can increase heart failure risk.
187
What is the #1 cause patients seek medical care?
Troublesome cough
188
Diflunisal
NSAID
189
Ibuprofen (Advil, Motrin)
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
190
Bismuth subsalicylate (Pepto-Bismol)
Mucosal protective agent. DON'T give with things that reduce acid (PPIs, H2 blockers, antacids)
Part of quadruple therapy against H. Pylori peptic ulcers. Anti-diarrheal. Decreases fluid secretion.
191
Lorazepam (Ativan)
Benzodiazepine. Tx anticipatory nausea
192
Tx viral infections in children
Acetaminophen (Tylenol)
193
Bisacodyl (Correctol)
Stimulates colon for laxative. AE: cramping
194
Mineral oil
suppositorie
195
Castor oil
Irritant laxative. CI pregnancy (can cause contractions)
196
Sitagliptin
Dipeptidyl Peptidase-IV Inhibitors
197
Dexamethasone
Corticosteroid. Supression test for cushing's syndome dx, Fetal lung maturation before birth. Tx chemo nausea
198
Polyethylene glycol
Osmotic laxative holds water
199
Dexlansoprazole
Proton pump inhibitor, prodrug gets intestinally abosrbed to inhbit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
200
Oxytocin (Pitocin)
Posterior pituitary, not oral
201
Canagliflozin
Na-Glu Cotransporter 2 inhibitor. Helps higher urination of glucose. AE: UTIs, urinary frequency, hypotension
202
Cimetidine (Tagamet)
H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: inhibits CP450 metabolism
