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Pharmacology II > Pharm 2 quiz 1 > Flashcards

Pharm 2 quiz 1 Flashcards

1
Q

Irbesartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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2
Q

Carvedilol

A

non-selective beta blocker (for HTN, angina, AND heart failure). MOA: Decreases CO and renin. This reduces negative effects of heart remodeling

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3
Q

Nisoldipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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4
Q

Bumetanide

A

Loop Diuretic, antiHTN, and heart failure med.MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance

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5
Q

Nitroprusside (Nitropress)

A

Parenteral agent (Vasodilator for HTN and heart failure). MoA: increases cGMP, > NO increases to cause rapid vasodiation

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6
Q

Atenolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

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7
Q

Hydrochlorothiazide (HCTZ)

A

Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance

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8
Q

Aliskiren

A

Renin inhibitor (for HTN), MOA: decreases blood volume

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9
Q

Milrinone

A

Inotrope (for heart failure). MOA: this phosphodiesterase inhibitor causes increase of cAMP, increases Ca

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10
Q

Diltiazem

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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11
Q

Fenoldopam

A

Parenteral agent (Vasodilator for HTN). MOA: Peripheral dopamine-1 receptor agonist to increase renal blood flow

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12
Q

Metoprolol

A

Beta 1 blocker (for HTN, angina AND heart failure). Decreases CO and renin and increases NO production causing vasodilation. This reduces negative effects of heart remodeling

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13
Q

Methazolamide

A

Carbonic Anhydrase Inhibitors (diuretic). MOA: CAI affects proximal convoluted tubule, reduces Na/Cl/bicarb reabsorption, excretes water/K/some Na
.

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14
Q

Isosorbide mononitrate (Imdur, Ismo)

A

Organic Nitrate (for angina) MOA: Increases NO and cGMP (both for dilation)

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15
Q

Prazosin (Minipress)

A

Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle

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16
Q

Hydralazine

A

Vasodilator (for HTN and heart failure). MOA: Increases NO

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17
Q

Acebutolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

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18
Q

Nicardipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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19
Q

Ranolazine (Ranexa)

A

Sodium channel blocker (for angina). MOA: Inhibits late phase of Na current to improve diastolic function

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20
Q

Propranolol

A

non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin

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21
Q

Losartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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22
Q

Telmisartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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23
Q

Enalapril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

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24
Q

Benazepril (Lotensin)

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

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25
Moexipril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
26
Esmolol
Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation
27
Clevidipine
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
28
Azilsartan
Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.
29
Terazosin (Hytrin)
Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle
30
Valsartan
Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.
31
Eprosartan
Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.
32
Spironolactone (Aldactone)
“Potassium-Sparing” Diuretic, antiHTN, (also for heart failure). MOA: inhibits aldosterone receptors in collecting tubule, causing Na/water excretion (retains K/H). lowers peripheral resistance; relieves adema and cardiac work load
33
Cilazapril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
34
Inamrinone
Inotrope (for heart failure). MOA: this phosphodiesterase inhibitor causes increase of cAMP, increases Ca
35
Quinapril (Accupril)
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
36
Felodipine
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
37
Ramipril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
38
Lisinopril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
39
Doxazosin
Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle
40
Candesartan
Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.
41
Isradipine
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
42
Indapamide
Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K and water excretion (retains Ca). lowers peripheral resistance
43
Torsemide
Loop Diuretic, antiHTN, and heart failure med. MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance
44
Nitroglycerin
Organic Nitrate (for angina) MOA: Increases NO and cGMP (both for dilation)
45
Amlodipine (Norvasc)
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
46
Nebivolol
Beta 1 blocker (for HTN, angina AND heart failure). Decreases CO and renin and increases NO production causing vasodilation. This reduces negative effects of heart remodeling
47
Methyldopa
Centrally acting alpha-2 agonist (for HTN). MOA: Lowers CO
48
Metolazone
Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance
49
Captopril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
50
Mannitol (Osmitroll)
Osmotic diuretic. MOA Carries water with it as it filters through glomerulus
51
Olmesartan
Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.
52
Chlorthalidone
Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance
53
Nifedipine (Procardia)
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
54
Acetazolamide (Diamox)
Carbonic Anhydrase Inhibitors (diuretic). MOA: CAI affects proximal convoluted tubule, reduces Na/Cl/bicarb reabsorption, excretes water/K/some Na .
55
Furosemide (Lasix)
Loop Diuretic, antiHTN, and heart failure med. MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance
56
Clonidine
Centrally acting alpha-2 agonist (for HTN). MOA: Lowers CO
57
Eplerenone (Inspra)
“Potassium-Sparing” Diuretic, antiHTN, (also for heart failure). MOA: inhibits aldosterone receptors in collecting tubule, causing Na/water excretion (retains K/H). lowers peripheral resistance; relieves adema and cardiac work load
58
Dopamine
Beta agonist (for heart failure) MOA: Increases contraction of heart
59
Ethacrynic acid
Loop Diuretic, antiHTN, and heart failure med. MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance
60
Perindopril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
61
Verapamil
Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction
62
Bisoprolol
Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation
63
Trandolapril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
64
Labetalol
non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin
65
Minoxidil
Vasodilator (for HTN). MOA: opens K channels that hypopolarize smooth muscle
66
Digoxin
Inotrope (for heart failure). MOA: increases Ca by inhibiting Na/K pump
67
Nadolol
non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin
68
Fosinopril
ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention
69
Dobutamine
Beta agonist (for heart failure). MOA: Increases contraction of heart
70
Isosorbide dinitrate (Dilatrate-SR, Isordil)
Organic Nitrate (for angina and heart failure). MOA: Increases NO and cGMP (both for dilation)

Pharmacology II (7 decks)

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