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Pharmacology II > Pharm 2 quiz 1 > Flashcards

Pharm 2 quiz 1 Flashcards

1
Q

Irbesartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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2
Q

Carvedilol

A

non-selective beta blocker (for HTN, angina, AND heart failure). MOA: Decreases CO and renin. This reduces negative effects of heart remodeling

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3
Q

Nisoldipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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4
Q

Bumetanide

A

Loop Diuretic, antiHTN, and heart failure med.MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance

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5
Q

Nitroprusside (Nitropress)

A

Parenteral agent (Vasodilator for HTN and heart failure). MoA: increases cGMP, > NO increases to cause rapid vasodiation

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6
Q

Atenolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

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7
Q

Hydrochlorothiazide (HCTZ)

A

Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance

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8
Q

Aliskiren

A

Renin inhibitor (for HTN), MOA: decreases blood volume

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9
Q

Milrinone

A

Inotrope (for heart failure). MOA: this phosphodiesterase inhibitor causes increase of cAMP, increases Ca

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10
Q

Diltiazem

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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11
Q

Fenoldopam

A

Parenteral agent (Vasodilator for HTN). MOA: Peripheral dopamine-1 receptor agonist to increase renal blood flow

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12
Q

Metoprolol

A

Beta 1 blocker (for HTN, angina AND heart failure). Decreases CO and renin and increases NO production causing vasodilation. This reduces negative effects of heart remodeling

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13
Q

Methazolamide

A

Carbonic Anhydrase Inhibitors (diuretic). MOA: CAI affects proximal convoluted tubule, reduces Na/Cl/bicarb reabsorption, excretes water/K/some Na
.

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14
Q

Isosorbide mononitrate (Imdur, Ismo)

A

Organic Nitrate (for angina) MOA: Increases NO and cGMP (both for dilation)

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15
Q

Prazosin (Minipress)

A

Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle

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16
Q

Hydralazine

A

Vasodilator (for HTN and heart failure). MOA: Increases NO

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17
Q

Acebutolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

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18
Q

Nicardipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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19
Q

Ranolazine (Ranexa)

A

Sodium channel blocker (for angina). MOA: Inhibits late phase of Na current to improve diastolic function

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20
Q

Propranolol

A

non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin

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21
Q

Losartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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22
Q

Telmisartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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23
Q

Enalapril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

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24
Q

Benazepril (Lotensin)

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

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25
Q

Moexipril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

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26
Q

Esmolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

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27
Q

Clevidipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

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28
Q

Azilsartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

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29
Q

Terazosin (Hytrin)

A

Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle

30
Q

Valsartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

31
Q

Eprosartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

32
Q

Spironolactone (Aldactone)

A

“Potassium-Sparing” Diuretic, antiHTN, (also for heart failure). MOA: inhibits aldosterone receptors in collecting tubule, causing Na/water excretion (retains K/H). lowers peripheral resistance; relieves adema and cardiac work load

33
Q

Cilazapril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

34
Q

Inamrinone

A

Inotrope (for heart failure). MOA: this phosphodiesterase inhibitor causes increase of cAMP, increases Ca

35
Q

Quinapril (Accupril)

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

36
Q

Felodipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

37
Q

Ramipril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

38
Q

Lisinopril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

39
Q

Doxazosin

A

Alpha blocker (for HTN). MOA: Relaxes arterial and venous smooth muscle

40
Q

Candesartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

41
Q

Isradipine

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

42
Q

Indapamide

A

Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K and water excretion (retains Ca). lowers peripheral resistance

43
Q

Torsemide

A

Loop Diuretic, antiHTN, and heart failure med.MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance

44
Q

Nitroglycerin

A

Organic Nitrate (for angina) MOA: Increases NO and cGMP (both for dilation)

45
Q

Amlodipine (Norvasc)

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

46
Q

Nebivolol

A

Beta 1 blocker (for HTN, angina AND heart failure). Decreases CO and renin and increases NO production causing vasodilation. This reduces negative effects of heart remodeling

47
Q

Methyldopa

A

Centrally acting alpha-2 agonist (for HTN). MOA: Lowers CO

48
Q

Metolazone

A

Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance

49
Q

Captopril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

50
Q

Mannitol (Osmitroll)

A

Osmotic diuretic. MOA Carries water with it as it filters through glomerulus

51
Q

Olmesartan

A

Angiotensin-2-receptor blockers (for HTN and heart failure) MOA: Reduces water retention; decreased preload and afterload for increased CO.

52
Q

Chlorthalidone

A

Thiazide diuretic, antiHTN, and heart failure med. MOA: inhibits Na/Cl cotransporter in the distal convoluted tubule, causing Na,Cl, K, and water excretion (retains Ca). lowers peripheral resistance

53
Q

Nifedipine (Procardia)

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

54
Q

Acetazolamide (Diamox)

A

Carbonic Anhydrase Inhibitors (diuretic). MOA: CAI affects proximal convoluted tubule, reduces Na/Cl/bicarb reabsorption, excretes water/K/some Na
.

55
Q

Furosemide (Lasix)

A

Loop Diuretic, antiHTN, and heart failure med.MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance

56
Q

Clonidine

A

Centrally acting alpha-2 agonist (for HTN). MOA: Lowers CO

57
Q

Eplerenone (Inspra)

A

“Potassium-Sparing” Diuretic, antiHTN, (also for heart failure). MOA: inhibits aldosterone receptors in collecting tubule, causing Na/water excretion (retains K/H). lowers peripheral resistance; relieves adema and cardiac work load

58
Q

Dopamine

A

Beta agonist (for heart failure) MOA: Increases contraction of heart

59
Q

Ethacrynic acid

A

Loop Diuretic, antiHTN, and heart failure med.MOA: Inhibits Na/K/2Cl cotransporter in ascending loop of Henle, causing Na, K, Ca, and water excretion. lowers peripheral resistance

60
Q

Perindopril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

61
Q

Verapamil

A

Calcium channel blocker (vasodilator for HTN and Angina). MOA: Dilates arteries by blocking inward Ca to prevent muscle contraction

62
Q

Bisoprolol

A

Beta 1 blocker (for HTN and angina). MOA: Decreases CO and renin and increases NO production causing vasodilation

63
Q

Trandolapril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

64
Q

Labetalol

A

non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin

65
Q

Minoxidil

A

Vasodilator (for HTN). MOA: opens K channels that hypopolarize smooth muscle

66
Q

Digoxin

A

Inotrope (for heart failure). MOA: increases Ca by inhibiting Na/K pump

67
Q

Nadolol

A

non-selective beta blocker (for HTN, angina). MOA: Decreases CO and renin

68
Q

Fosinopril

A

ACE inhibitor (for HTN and heart failure). MOA: Decreases angiotensin II and increases bradykinin, reducing water retention

69
Q

Dobutamine

A

Beta agonist (for heart failure). MOA: Increases contraction of heart

70
Q

Isosorbide dinitrate (Dilatrate-SR, Isordil)

A

Organic Nitrate (for angina and heart failure). MOA: Increases NO and cGMP (both for dilation)

Pharmacology II (7 decks)

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