Pharm 2 quiz 2

Question 1

Mirtazapine

Answer 1

Atypical antidepressant. alpha 2 blocker, enhances 5HT and NE neurotransmission.

Question 2

Eszopiclone

Answer 2

Benzodiazepine-like drug. short-term binds to GABA receptor to enhance GABA. Tx insomnia

Question 3

Duloxetine (Cymbalta)

Answer 3

5HT/NE reuptake inhibitors. Tx depression (associated with chronic pain)

Question 4

Escitalopram (Lexapro)

Answer 4

SSRI. Tx depression

Question 5

Naltrexone

Answer 5

Tx alcohol dependence. opiate antagonist.

Question 6

Paroxetine (Paxil)

Answer 6

SSRI. Tx depression

Question 7

Doxepin

Answer 7

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 8

Protriptyline

Answer 8

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 9

Thioridazine

Answer 9

1st generation antipsychotic. D2 antagonist

Question 10

Chlorpromazine (Thorazine)

Answer 10

1st generation antipsychotic. D2 antagonist

Question 11

Alprazolam (Xanax)

Answer 11

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release.

Question 12

Thiothixene

Answer 12

1st generation antipsychotic. D2 antagonist

Question 13

Flurazepam

Answer 13

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 14

Selegiline

Answer 14

MAOI. Tx depression

Question 15

Venlafaxine (Effexor)

Answer 15

5HT/NE reuptake inhibitors. Tx depression (associated with chronic pain)

Question 16

Secobarbital

Answer 16

Barbiturate. binds to GABA receptor to enhance GABA.

Question 17

Disulfiram

Answer 17

Tx alcohol dependence. inhibits aldehyde dehydrogenase

Question 18

Imipramine

Answer 18

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 19

Haloperidol (Haldol)

Answer 19

1st generation antipsychotic. D2 antagonist

Question 20

Phenobarbital

Answer 20

Barbiturate. binds to GABA receptor to enhance GABA.

Question 21

Citalopram (Celexa)

Answer 21

SSRI. Tx depression

Question 22

Zaleplon

Answer 22

Benzodiazepine-like drug. short-term binds to GABA receptor to enhance GABA. Tx insomnia

Question 23

Lithium

Answer 23

Tx Mania. MOA unknown

Question 24

Estazolam

Answer 24

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 25

Midazolam (Versed)

Answer 25

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 26

Pentobarbital (Nembutal)

Answer 26

Barbiturate. binds to GABA receptor to enhance GABA.

Question 27

Triazolam

Answer 27

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 28

Quetiapine (Seroquel)

Answer 28

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 29

Carbamazepine

Answer 29

Tx mania (and epilepsy). Targets voltage-gated Na channels.

Question 30

fluphenazine

Answer 30

1st generation antipsychotic. D2 antagonist

Question 31

Ziprasidone

Answer 31

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 32

Zolpidem

Answer 32

Benzodiazepine-like drug. short-term binds to GABA receptor to enhance GABA. Tx insomnia

Question 33

Aripiprazole (Abilify)

Answer 33

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 34

Nefazodone

Answer 34

weak 5HT reuptake inhibitor. Atypical antidepressant

Question 35

Fluoxetine

Answer 35

SSRI. Tx depression

Question 36

Clonazepam (Klonopin)

Answer 36

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 37

Oxazepam

Answer 37

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 38

Temazepam

Answer 38

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 39

Chlordiazepoxide (Librium)

Answer 39

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 40

Olanzapine

Answer 40

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 41

Buspirone

Answer 41

5HT receptor agonist. Tx anxiety

Question 42

Nortriptyline

Answer 42

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 43

Sertraline

Answer 43

SSRI. Tx depression

Question 44

Bupropion (Wellbutrin, Zyban)

Answer 44

weak 5HT/NE reuptake inhibitors. Atypical antidepressant

Question 45

Lorazepam

Answer 45

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 46

Clorazepate

Answer 46

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 47

Acamprosate

Answer 47

Tx alcohol dependence. uknown MOA

Question 48

Trazodone

Answer 48

weak 5HT reuptake inhibitor. Atypical antidepressant

Question 49

Clomipramine

Answer 49

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 50

Phenelzine

Answer 50

MAOI. Tx depression

Question 51

Diazepam (Valium)

Answer 51

Benzodiazepine. binds to GABA receptor to enhance GABA; also decreases GABA release

Question 52

Flumazenil

Answer 52

Benzodiazepine blocker. reverses anesthesia

Question 53

Desipramine

Answer 53

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 54

Amitriptyline

Answer 54

Tricyclic antidepressants. block reuptake of NE and 5HT (but not DA)

Question 55

Ramelteon (Rozerem)

Answer 55

Melatonin receptor agonist. other hypnotic. Tx insomnia

Question 56

Risperidone

Answer 56

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 57

Clozapine

Answer 57

2nd generation antipsychotic. D2 antagonist (and D3, D4, 5HT blocker)

Question 58

Valproic acid

Answer 58

Tx mania (and epilepsy). Targets voltage-gated Na channels

Question 59

Tranylcypromine

Answer 59

MAOI. Tx depression