Final exam (fixed spelling) Flashcards
1
Q
Hydrocortisone
A
Corticosteroid, tx primary adrenocortical insufficiency (Addison’s). Also 2ary 3ary, Identical to cortisone
2
Q
Indomethacin
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
3
Q
Ketorolac (Acular, Acuvail, Toradol)
A
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
4
Q
Metoclopramide (Reglan)
A
Blocks DA receptors tx chemo nausea. AE: sedation, diarrhea, extrapyramidal symptoms
5
Q
Etodolac
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
6
Q
Droperidol
A
Blocks DA receptors. Tx chemo nausea
7
Q
Norethindrone
A
Progestogens. Daily Progestin-only pill for contraceptive. MORE STABLE to first pass metabolism. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
8
Q
Formoterol
A
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
9
Q
Flutamide
A
Antiandrogens Tx prostatic carcinoma
10
Q
Glyburide
A
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
11
Q
Fludrocortisone
A
Mineralocorticoid
12
Q
Glipizide
A
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
13
Q
Haloperidol (Haldol)
A
Blocks DA receptors. Tx chemo nausea
14
Q
vasopressin / ADH
A
Posterior pituitary, not oral, tx diabetes insipidus
15
Q
Dextromethorphan
A
Morphine derivative. Tx cough, low addictive profile (but still possible), equally effective like codeine
16
Q
Repaglinide
A
Meglitinide, Stimulates beta cells to make insulin. 3 hour duration. Good for irregular meals. AE: weight gain
17
Q
Budesonide
A
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if “spacer” is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
18
Q
Sulindac
A
(NSAID)Acetic Acid derivatives, Lower therapeutic index :(
19
Q
Aprepitant
A
Substance P blocker. Tx chemo nausea. Targets neurokinin receptor in brain
20
Q
Psyllium (Metamucil)
A
Bulk laxative. Water retention increases GI movement
21
Q
Propylthiouracil
A
Inhibits thyroid hormone synthesis, tx hyperthyroidism, short half life
22
Q
Sodium bicarbonate
A
Antacid. Tx peptic ulcer symptoms. AE systemic alkalosis
23
Q
Medroxyprogesterone
A
Progestogens. INJECTIBLE. MORE STABLE to first pass metabolism. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
24
Q
Prednisone
A
Corticosteroid. Preferred in pregnancy
25
Diclofenac (Voltaren)
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
26
Methylcellulose (Citrucel)
Bulk laxative. Water retention increases GI movement
| Adsorbent Anti-diarrheal
27
Meloxicam
(NSAID)Oxicam Derivatives - long half lives. UNIQUE: COX 2 selective at low doses
28
Latanoprost (Xalatan)
PGF analog. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increased iris pigmentation, eyelashes, and normally causes red eye
29
gold salts
DMARD. Suppresses phagocytosis of macrophages, delayed effect, has serious AE
30
Rabeprazole
Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
31
Norelgestromin
Progestogens. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
32
Aluminum hydroxide
Antacid and adsorbent antidiarrheal
33
Drospirenone With ethinyl estradiol (YAZ)
Progestogens, can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
34
Flunisolide
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
35
Lansoprazole
(Prevacid) Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
36
Amoxicillin
Aminopenicillin, beta-lactam abx, prevents elongation of peptidoglycans. Part of triple therapy against H. Pylori peptic ulcers.
37
Acarbose
α-Glucosidase Inhibitors(for DB) to prevent upper GI carb digestion to decrease postprandial release of glucose. Taken just before meals. AE: flatulence, GI problems (avoid if have IBD)
38
What drugs can increase iris pigmentation and increased eyelashes?
Latanoprost Travoprost Bimatoprost
39
Lactulose
Osmotic laxative holds water
40
Ciclesonide
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
41
Ketoprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
42
Zafirlukast
Leukotriene antagonist. Blocks effects of leuk. Tx asthma
43
Clarithromycin
Part of triple therapy against H. Pylori peptic ulcers.
44
Methimazole
Inhibits thyroid hormone synthesis, tx hyperthyroidism, short half life
45
Magnesium citrate
Osmotic laxative holds water
46
Cetirizine
(Zyrtec) H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation). Tx motion sickness
47
Indacaterol
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
48
Metronidazole
Part of triple or quadruple therapy against H. Pylori peptic ulcers.
49
Methylcellulose (Citrucel)
Bulk laxative increases water retention in GI tract
50
Leflunomide
DMARD.Decreases pyrimidine synthesis in lymphocytes. Ci pregnancy
51
Guaifenesin
Unknown MOA. Cough expectorant (bonus: reduces cough)
52
Which corticosteroid is preferred in pregnancy?
Prednisone
53
What is the precursor of prostaglandins?
Arachidonic acid
54
Adalimumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
55
Empagliflozin
Na-Glu Cotransporter 2 inhibitor. Helps higher urination of glucose. AE: UTIs, urinary frequency, hypotension
56
Dutasteride
Antiandrogens Tx BPH
57
Bimatoprost (Lumigan, Latisse)
Prostaglandin analog. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increased iris pigmentation, eyelashes, and normally causes red eye
58
Rosiglitazone
Thiazolidinedione. Improves whole-body insulin sensitivity. Combination with insulin can increase heart failure risk.
59
Fluticasone (Flovent)
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
60
What's a common treatment for COPD?
-tropium (muscarinic blocker) and -erol (beta 2 agonist)
61
Why taper steroids?
So the low ACTH levels can gradually increase and return to normal
62
Oxaprozin
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
63
Oral contraceptives vs Hormone therapy levels?
Dose is less in HT than contraception
64
Esomeprazole (Nexium)
Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
65
Acetaminophen (Tylenol)
SUBSTITUTE for nsaid. Prostaglandin synthesis inhibitor in CNS. Weak anti-inflammatory, does not affect platelet function. Tx viral infections in children. Hepatic necrosis at high doses
66
Diphenoxylate + atropine
Opioid-like effect on GI to slow GI tract. Tx Diarrhea
67
liothyronine
T3 substitute in hypothyroidism (long half-life)
68
thyroid stimulating hormone
Made by anterior pituitary, causes uptake of iodine and T4 T3 synthesis. Inducing P450 system accelerates metabolism of thyroid hormones
69
Senna
Stimulant laxative
70
human menopausal gonadotropin
Gonadotropin, treat infertility
71
Certolizumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
72
Metformin
- increases liver sensitivity to insulin, inc skeletal muscle glucose uptake, renal cleared, dec hepatic glucose production. Avoid with alcohol abuse. Common GI distress
- drug of choice for newly diagnosed type 2DB
73
What drug is the "morning-after pill"?
High dose estrogen plus progestin
74
Omalizumab
Binds to IgE, tx asthma. Costly
75
Illoprost
Prostacyclin analog to increase cAMP, given via inhalation
76
pred forte
Corticosteroid
77
Exenatide
Glucagon-Like Polypeptide-1 Agonists. Helps suppress glucagon and enhances glucose-mediated insulin secretion. Injection only
78
Cromolyn
Mast cell stabilizer. Tx asthma, allergies. Prevention, not intervention for both diseases! Needs frequent dosing
79
Ranitidine
(Zantac) H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Longer acting, similar to Famotidine, more potent
80
What can be used orally for prostate cancer?
Bicalutamideand Nilutamide (Flutamide not oral)
81
Prolactin
Lactation, decreases reproductive function
82
What is ci for NSAIDS?
Post-op pain of coronary artery bypass graft.
83
Sucralfate
Mucosal protective agent. DON'T give with things that reduce acid (PPIs, H2 blockers, antacids)
84
Magnesium hydroxide
Antacid. And Osmotic laxative that holds water
85
What does the Middle zona fasciculata produce?
Glucocorticoids (involved in metabolism and stress)
86
Mometasone
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
87
Naproxen
(Aleve) (NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
88
Travoprost (Travatan Z)
Prostaglandin pro-drug. Binds to Prostaglandin FP receptor to increase uveoscleral outflow. Increased iris pigmentation, eyelashes, and normally causes red eye
89
What is the treatment escalation of type 2 diabetes?
Start with lifestyle and metformin. Then add sulfonylurea (Gli- Gly-) or insulin Then Thiazolidinedione (-zone) or GLP-1 receptor agonist. -(u/a)tide
90
Triamcinolone (Kenalog)
Corticosteroid
91
Methylprednisolone (Medrol)
Corticosteroid. Tx inflammation
| Tx chemo nausea
92
Nilutamide
Antiandrogens. Oral treatment of prostate cancer
93
Methotrexate
DMARD. Immunosuppressant
94
Liraglutide
Glucagon-Like Polypeptide-1 Agonists. Helps suppress glucagon and enhances glucose-mediated insulin secretion. Injection only. CI family history of cancer
95
Eplerenone (Inspra)
k-sparing diuretic, aldosterone blocker
96
Prednisolone
Corticosteroid.
97
Aspirin
NSAID Irreversibly inactivates cyclooxygenase. Only lowers fevers, not normal body temps. Increase ventilation, less intestinal protective mucus, lower thromboxane production (less platelet aggregation). CAN CAUSE REYE SYNDROME. 1st or 0 order elimination kidney extracted
98
Megestrol
Progestogens MORE STABLE to first pass metabolism. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
99
Pramlintide
Amylin analog. Delays gastric emptying to reduce needed insulin dose and improves satiety. Injected.
100
Which progestins are more stable?
Medroxyprogesterone, Megestrol, Norethindrone
101
Cox-1 or Cox-2 inhibition has fewer side effects?
Cox 2
102
Finasteride
Antiandrogens Tx BPH
103
Fenoprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
104
Cortisone
Corticosteroid
105
Palonosetron
5-HT3 blocker. Tx chemo nausea.
106
Benzonatate
Local anesthetic for respiratory passage to reduce cough reflex
107
Mifepristone
Progesterone antagonist. 1st trimester abortion
108
Pirbuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
109
Pantoprazole
Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
110
Tolmetin
(NSAID)Heteroaryl Acetic Acids.- approved for long-term use. Ophthalmically available
111
Progesterone
Progestogens. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
112
Granisetron
5-HT3 blocker. Tx chemo nausea.
113
Golimumab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
114
Nabumetone
NSAID. Low AE
115
Tamoxifen
Selective Estrogen-Receptor Modulator (SERM), tx breast cancer. P450 metabolized, bile excreted.
ae: crystalline retinopathy
116
Docusate
Stool softener (constipation prevention)
117
Piroxicam
(NSAID)Oxicam Derivatives - long half lives
118
Celecoxib
(Celebrex) NSAID, more COX-2 selective for better pain management. Does not affect blood, but has other NSAID AE
119
How are Glucocorticoids and DMARDS implemented in disease therapy?
Glucocorticoids are used in rheumatoid arthritis until DMARDs kick in.
120
Chloroquine
DMARD. tx malaria (prevent heme metabolism (toxic to parasite, increases pH)). AE: Bull's eye maculopathy
121
Levothyroxine
Tx hypothyroidism and thyroid replacement (long-half-life), T4 substitute
122
Tetracycline
Part of quadruple therapy against H. tx Pylori peptic ulcers.
MOA Binds to 30s ribosome subunit, stops addition of new AAs
ae:phototoxicity, pseudotumor cerebri, vertigo; ci: kids
123
Glycerin
suppository
124
Saxagliptin
Dipeptidyl Peptidase-IV Inhibitors. Use with diet and exercise
125
When should you not use an ocular steroid?
Do NOT use a (cortico)steroid for Herpes simplex EPITHELIAL keratitis
Also avoid for large corneal epithelial defects
126
What drug is nearly 100% bioavailable
Nizatidine (H2 blocker) has no liver metabolism
127
Codeine
Opiate. Gold standard for cough suppression. Decreases mucosal secretion
128
Ondansetron
5-HT3 blocker. Tx chemo nausea.
129
Theophylline
Increases cAMP for tx chronic asthma, drug is phased out because narrow TI. AE: Fatal arrhythmias
130
follicle-stimulating hormone
Gonadotropin, treat infertility
131
Beclomethasone
Inhaled corticosteroid, reduces inflammation. Tx asthma, allergies. Can be discontinued in 1-2 weeks. Few systemic effects if "spacer" is used (so all drug goes to lungs). AE: lower immunity can cause candidiasis
132
Raloxifene
Selective Estrogen-Receptor Modulator (SERM), bile excreted
133
Dolasetron
5-HT3 blocker. Tx chemo nausea.
134
Miglitol
α-Glucosidase Inhibitors(for DB) to prevent upper GI carb digestion to decrease postprandial release of glucose. Taken just before meals. AE: flatulence, GI problems (avoid if have IBD)
135
Diphenhydramine
(Benadryl) H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
136
Misoprostol
PGE1 analog on parietal cells protects mucosal lining of stomach from NSAIDs. Can induce labor (and abortion)
137
Corticotropin
ACTH is made by anterior pituitary. Drug is a diagnostic tool for adrenal insufficiency
138
What does the Inner zona reticularis produce?
Androgens
139
Lubiprostone
Laxative. Activates Cl channel to increase fluid secretion into intestine. NO POTENTIAL FOR DEPENDENCY. Tx: chronic constipation. AE: nausea
140
What can androgens treat?
Low testosterone males,
osteoporosis and wasting from HIV/cancer
severe burn healing
Endometriosis
141
Meclofenamate
(NSAID) Fenamate. Severe side effects
142
Calcium carbonate (Tums)
Antacid. Tx peptic ulcer symptoms
143
Somatostatin
suppress GH and TSH, tx tumors
144
Somatotropin
Synthetic GH
145
Linagliptin
DPP-4 inhibitor, inc insulin dec glucagon
146
Loratadine
(Claritin) H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
147
Salmeterol
Beta 2 agonist, longer acting (12+ hours), slow onset. No anti-inflammatory effect
148
Prochlorperazine (Compazine)
Block DA receptors. Tx chemo nausea. AE: hypotension, restlessness, extrapyramidal symptoms
149
Montelukast (Singulair)
Leukotriene antagonist. Tx asthma and allergic rhinitis
150
Loperamide
(Imodium A-D) Opioid-like effect on GI to slow GI tract. Tx Diarrhea
151
Etanercept
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
152
Levalbuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
153
Estrogens has what AE?
Increase cervical cancer risk but lowers endometrial and ovarian cancer risk. weight gain. enhances serum lipids
154
Nateglinide
Meglitinide, Stimulates beta cells to make insulin. 3 hour duration. Good for irregular meals. AE: weight gain
155
Betamethasone
Corticosteroid. Fetal lung maturation before birth
156
Levonorgestrel
Progestogens. can cause acne, HA, depression, weight gain. Tx hormonal deficiency, contraception (in combination),
157
D-penicillamine
DMARD. Cysteine analog that Slows progression of bone destruction and RA. Short-term tx only. Don't combine with other DMARDs
158
Flurbiprofen
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
159
What are the side effects of corticosteroids?
Decreased growth in children, glaucoma, central fat, osteoporosis, infection risk, hair growth, increased appetite, peptic ulcer, hypertension, edema, hypokalemia, POSTERIOR SUBCAPSULAR CATARACT
160
Estriol
Metabolite of estradiol, Produced by the placenta
161
Gonadorelin
Posterior pituitary hormone.
| synthetic GnRH, tx prostate cancer, endometriosis, precocious puberty
162
Tobradex
Corticosteroid
163
Tiotropium (Spiriva)
Muscarinic blocker. Tx asthma (inhaled) (and helps COPD). Not as good as Beta 2 agonist for asthma.
Tx motion sickness
164
Spironolactone (Aldactone)
k-sparing diuretic, aldosterone blocker
165
What does the Outer zona glomerulosa produce?
Mineralocorticoids (aldosterone)
166
Anakinra
Interleukin-1 receptor antagonist. Daily subcutaneous injection. Don't combine with TNF inhibitors. Tx Rheumatoid arthritis
167
Nizatidine
H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Nearly 100% bioavailable
168
Albuterol
Beta 2 agonist, short acting. No anti-inflammatory effect
169
Ketoconazole
Antifungal that Strongly inhibits all gonadal and adrenal steroid hormone synthesis, tx cushing's
170
Alprazolam
(Xanax) Benzodiazepine. Tx anticipatory nausea
171
Infliximab
TNF Inhibitor. Tx rheumatoid arthritis. Can be combined with DMARD.Subcutaneous/ IV administration. Increased risk of infection/ lymphoma or other cancers.
172
Zileuton
Leukotriene antagonist. Prevents leuk. Formation. Tx asthma
173
Famotidine
(Pepcid) H2 blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: Similar to ranitidine, most potent.
174
human chorionic gonadotropin
Gonadotropin, treat infertility
175
Estrone
Metabolite of estradiol,Primary circulating estrogen after menopause
176
Ipratropium (Atrovent)
Muscarinic blocker. Tx asthma (inhaled) (and helps COPD). Not as good as Beta 2 agonist for asthma. Tx motion sickness
177
Which progestin can be a daily contraceptive?
Norethindrone
178
What can treat BPH?
Finasteride and dutasteride
179
Omeprazole (Prilosec)
Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs. UNIQUE: can interfere with warfarin metabolism
180
Bicalutamide
Antiandrogens. Oral treatment of prostate cancer
181
Fexofenadine
(Allegra) H1 blocker. AE: Sedation and anticholinergic effects (dry eyes, mouth, constipation) Tx motion sickness
182
Which progestin is injectible?
Medroxyprogesterone
183
Glimepiride
Sulfonylurea. Stimulates beta cells to make insulin by closing K channels to cause depolarization. First-line therapy, esp for non-overweight pts. CI: alcoholism can induce hypoglycemia. AE: weight gain
184
What are testosterone AE?
Female masculinization
Males: Impotence, decreased spermatogenesis, gynecomastia, prostate growth
Lowers HDL and raises LDL :(
185
Pioglitazone
Thiazolidinedione. Improves whole-body insulin sensitivity. Combination with insulin can increase heart failure risk.
186
What is the #1 cause patients seek medical care?
Troublesome cough
187
Diflunisal
NSAID
188
Ibuprofen (Advil, Motrin)
(NSAID) Propionic acid derivative, reversibly inactivates cyclooxygenase
189
Bismuth subsalicylate (Pepto-Bismol)
Mucosal protective agent. Tx recovering ulcers. DON'T give with things that reduce acid (PPIs, H2 blockers, antacids)
Part of quadruple therapy against H. Pylori peptic ulcers. Anti-diarrheal. Decreases fluid secretion.
190
Lorazepam
(Ativan) Benzodiazepine. Tx anticipatory nausea
191
Tx viral infections in children
Acetaminophen (Tylenol)
192
Bisacodyl (Correctol)
Stimulates colon for laxative. AE: cramping
193
Mineral oil
suppository
194
Castor oil
Irritant laxative. CI pregnancy (can cause contractions)
195
Sitagliptin
Dipeptidyl Peptidase-IV Inhibitors
196
Dexamethasone
Corticosteroid. Suppression test for cushing's syndrome dx, Fetal lung maturation before birth. Tx chemo nausea
197
Polyethylene glycol
Osmotic laxative holds water
198
Dexlansoprazole
Proton pump inhibitor, prodrug gets intestinally absorbed to inhibit H+ efflux from parietal cells. Tx erosive esophagitis, duodenal ulcer, GERD (take before breakfast). H2 blockers (-tidine) hinder PPIs
199
Oxytocin (Pitocin)
Posterior pituitary, not oral
200
Canagliflozin
Na-Glu Cotransporter 2 inhibitor. Helps higher urination of glucose. AE: UTIs, urinary frequency, hypotension
201
Cimetidine
H2 (Tagamet) blocker to reduce gastric acid secretion. Tx Peptic ulcers, Acute stress ulcers (tolerance may develop), GERD (slow onset). Crosses placenta. UNIQUE: inhibits CP450 metabolism
