pharm 201 E2 Flashcards

1
Q

Enalapril Class/Tx

A

ACE Inhibitor/Heart Failure

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2
Q

Enalapril AE

A

*Cough, *angioedema, hypoTN, increased K, fetal injury

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3
Q

Enalapril Nsg

A

*Recognize angioedema, monitor K, BP, cough, do NOT use in pregnancy

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4
Q

Carvedilol Class/Tx

A

Beta-Blocker/Heart Failure

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5
Q

Carvedilol AE

A

Bronchoconstriction, inhibits glycogenolysis (masks hypoglycemia), caution in DM

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6
Q

Carvedilol Nsg

A

Take BP & pulse before admin, monitor hypoglycemia, teach to never stop abruptly.

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7
Q

Carvedilol Fx

A

Improves LVEF, prolongs survival, increases ecercise tollerance.

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8
Q

Digoxin Class/Tx

A

Cardiac Glycoside/Heart Failure

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9
Q

Digoxin MOA

A

Positive inotropic action: increase force of ventricular contraction, increase cardiac output, decrease preload & afterload, decrease blood volume & water retention.

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10
Q

Digoxin AE

A

*Yellowish Halos (Toxicity), dysrhythmias, AV block, severe bradycardia, anorexia, N/V, fatigue, dizziness, blurred vision.

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11
Q

Digoxin Nsg

A

Monitor K, give slowly if IV.

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12
Q

Digoxin Toxicity

A

Hold Dig and K wasting diuretics, monitor K

Give Digibind if severe

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13
Q

Morphine Sulfate Class/Tx

A

Vasodilator/Heart Failure

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14
Q

Morphine Sulfate Nsg

A

Decreases preload and afterload, decreases myocardial oxygen demand on heart.

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15
Q

Quinidine Class/Tx

A

Na-Channel Blocker/Dysrhythmias

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16
Q

Quinidine AE

A

*Diarrhea, *tinnitus, vertigo, cardiotoxicity, arterial embolism, hypoTN, peripheral neuritis

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17
Q

Quinidine Contra

A

Conduction defects, complete AV block, caution in CHF, low K, and low Mg

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18
Q

Quinidine Nsg

A

*Take with food, *Assess apical pulse before admin, monitor ECG, BP, I&O, electrolytes (K), pain/numbness of extremities

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19
Q

Propranolol Class/Tx

A

Non-selective Beta-Blocker/Dysrhythmias

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20
Q

Propranolol AE

A

bronchospasm, heart failure, AV block, sinus arrest, hypoTN

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21
Q

Propranolol Contra

A

Asthma, COPD, sinus bradycardia, heart block, heart failure

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22
Q

Propranolol Nsg

A

*Do not stop abruptly, *Moderate Na (helps prevent fluid volume overload), w/hold med if HR

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23
Q

Diltiazem Class/Tx

A

Ca-Channel Blocker/Dysrhythmias

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24
Q

Diltiazem AE

A

bradycardia, AV block, heart failure, altered liver/kidney fx

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25
Diltiazem Contra
AV block, hypoTN, sick sinus syndrome, pulmonary congestion in MI
26
Diltiazem Nsg
Take before meals & @ HS, stop smoking and ETOH, change position slowly
27
HMG-CoA Reductase Inhibitors Class/Tx
"-statins"/decrease CHO concentration in liver
28
HMG-CoA Reductase Inhibitors AE
*hyperglycemia, myopathy, hepatotoxicity, rhabdomyolysis
29
HMG-CoA Reductase Inhibitors Contra
Active liver disease, pregnancy
30
HMG-CoA Reductase Inhibitors Nsg
*Take @ HS, not recommended for people younger than 20, monitor liver fx, lipid levels, may need low-fat diet.
31
Filgrastim Class/Tx
Granulocyte CSF/neutropenia
32
Filgrastim AE
*Bone Pain, leukocytosis, Splenomegaly
33
Filgrastim Nsg
*Do NOT shake vial, * Do not give w/in 24 hrs of Chemo, * Increases WBC production, monitor for infection
34
Cinacalcet Class/Tx
Calcimimetic/primary hyperparathyroidism
35
Cinacalcet AE
N/V/D, hypoCa
36
Cinacalcet NSG
*Give w/ food, monitor serum Phos & Ca, *IF hyperCa give Furosemide and Glucocorticoids.
37
Ca Acetate Tx
hyperPhos, mild hypoCa, supplement for dietary Ca.
38
Ca Acetate AE
Contipation, hyperCa, N/V, polyuria, lethargy, depression
39
Ca Acetate Contra
HyperCa, renal calculi, hypoPhos
40
Ca Acetate Nsg
*Must be taken w/ meals, separate from tetracyclines & thyroid drugs
41
Gemfibrozil Class/Tx
Fibric Acid/Lowers triglycerides
42
Gemfibrozil AE
*GI distress, *gallstones, myopathy & liver injury w/ Statins
43
Gemfibrozil Contra
Gallbladder disease, renal problems, liver or bilary cirrhosis, pregnancy
44
Gemfibrozil Nsg
*Take 30 minutes before breakfast & supper, *Assess bowel sounds
45
Gemfibrozil D-D
*Warfarin (increased bleeding time), statins (liver)
46
Niacin Class/Tx
Nicotinic Acid/Lowers LDL & triglycerides
47
Niacin AE
*Intense flushing, hepatotoxicity, hyperuricemia
48
Niacin Contra
*Caution in DM. Liver disease, severe gout
49
Niacin Nsg
*Report excess thirst, *increased appetite, *increased urine, *avoid direct exposure to sunlight, * take ASA 30 minutes before w/ COOL water to prevent flushing.
50
Colesevelam Class/Tx
Bile Acid Sequestrant/Lowers LDL
51
Colesevelam AE
*Constipation, bloating, indigestion
52
Colesevelam Contra
Biliary obstruction, DM
53
Colesevelam D-D
Can Decrease absorption of other meds, *take other meds 1 hr before or 4 hrs after
54
Colesevelam Nsg
*Take w/ food and no other meds, long-term can increase bleeding tendancy
55
Amiodarone Class/Tx
K-channel blocker/Tachy dysrhythmias
56
Amiodarone AE
Pulmonary toxicity, cardiotoxicity, skin discolorization (bluish gray), hepatits, thyroid toxicity
57
Amiodarone Contra
Cardiogenic shock, severe sinus brady, hepatic disease
58
Amiodarone Nsg
*No grapefruit juice, Assess pulmonary fx, monitor HR, BP, labs (liver), ECG
59
Isosorbide Mononitrate Class/Tx
Organic Nitrate (long-acting)/promotes vasodilation, decreases Oxygen demand
60
Isosorbide Mononitrate AE
*HA, hypoTN, dizziness
61
Isosorbide Mononitrate Contra
hypoTN, acute MI, CHF, volume depletion
62
Isosorbide Mononitrate Nsg
IV should be mixed in a glass bottle, Monitor BP & HR every 15 min if IV drip, keep nitro tabs @ bedside
63
Furosemide Class/Tx
Loop Diuretic/blocks reabsorption of Na & Cl, preventing water reabsorption
64
Furosemide AE
*hypoK, hypoNa, dehydration, hypoCl, hypoTN, ototoxicity
65
Furosemide D-D
Digoxin, aminoglycoside abx
66
Furosemide Nsg
Monitor K, change position slowly, daily weight
67
Spironolactone Class/Tx
K-sparing Aldosterone Agonist/Blocks aldosterone action in distal nephron
68
Spironolactone AE
*hyperK
69
Spironolactone D-D
drugs that raise K
70
Spironolactone Nsg
*Monitor K, insulin may be prescribed to control high K levels, avoid salt substitutes containing K
71
Epoetin Alpha Class/Tx
Hematopoietics/Stimulates erythrocyte production
72
Epoetin Alpha Uses
Chronic renal failure, Anemia 2nd to Chemo, Anemia in HIV
73
Epoetin AE
HTN, cardiovascular events
74
Epoetin Nsg
*Do not shake vial, Assess LOC, monitor for anemia, labs, dietary intake, blood clots
75
Ezetimibe Class
CHO lowering (inhibits CHO absorption)
76
Ezetimibe AE
*Rhabdomyolysis, *Hepatits, thrombocytopenia (elderly), pancreatitis
77
Ezetimibe Nsg
*CAN be used w/ "statins"
78
Ezetimibe Contra
caution in impaired liver fx
79
Nitro Class/Tx
Organic Nitrate (Short acting)/promotes vasodilation, decreases Oxygen demand
80
Nitro AE
*HA, hypoTN, reflex tachycardia
81
Nitro Contra
Cardiac tamponade, pericarditis, head injury, shock
82
Nitro Nsg
*For HA take Acetaminophen, should feel slight sting during application, must dissolve completely under tongue
83
HCTZ Class/Tx
Thiazide/block reabsorption of Na & Cl in early segment of distal convoluted tubule
84
HCTZ AE
*hypoK, dehydration, hypoNa, hypoCl
85
HCTZ D-D
Digoxin, NSAIDs
86
K AE
GI irritation, hyperK
87
K Nsg
Take oral w/ meals or full glass of water for GI irritation, IV should be diluted & given slowly
88
Beta Blockers in Angina
*Decreased Oxygen demand (block-beta1 receptors in heart, *Increased oxygen supply (decrease arterial pressure[afterload]), *Goal tnage for HR is 50-60 to give med, prevent pain of stable angina (decreased HR & contractility), not used for varient angina,
89
Clopidogrel Class/Tx
Anti-platelet/Unstable angina
90
Clopidogrel AE
*Hemorrhage, abd pain, dyspnea, diarrhea, rash
91
Clopidogrel Nsg
*monitor for bleeding, No in pregnancy, report weakness, HA, & dizziness, monitor heart rhythm for ST resolve
92
Clopidogrel Contra
*intracranial hemorrhage, *active GI bleed, PUD
93
Ramipril Class/Tx
ACE inhibitor/angina & STEMI
94
Ramipril uses
promotes water loss, decreases volume which lowers preload & afterload
95
Aspirin Class/TX
Antiplatelet/Angina
96
Aspirin Nsg
*chew the first dose, watch for bleeding