Pharm Flashcards
1
Q
preferred initial PD therapy:
A
D2R agonist
2
Q
MOA of apomorphine
A
NS D receptor agonist
3
Q
MOA of bromocriptine
A
D2 +/- D1 R agonist
4
Q
MOA of pramipexole
A
D2R agonist + free radical scavenger
5
Q
MOA ropinirole
A
D2R agonist (*CYP)
6
Q
CI = seizures, CHF
A
amantadine (antiviral, incr dopamine release)
7
Q
MOA of selegiline + rasagiline
A
MAO-B inh (used when Ldopa response decr)
8
Q
MOA of entacapone
A
periph COMT inh, proongs action of L dopa
9
Q
MOA of tolcapone
A
central and periph COMT inh, proongs action of L dopa
**hepatic failure
10
Q
CI for anticholinergics:
A
BPH, organic brain syndr, glaucoma, currently taking anti-H1 or TCAs
