Embryology Flashcards
3 vesicles = __ weeks
5 vesicles = __ weeks
4
5
Week #?
Neural plate is formed
3
Week #?
Closure of pores
4
Form all CNS neurons
neuroblasts
Glioblasts form:
radial glial cells, astrocytes, oligodendrites, ependymocytes, choroid plexus
When are radial glial cells formed?
before neuroblasts differentiate into neurons
Microglia arise from…
monocytes in the circulation (invade CNS –> cerebral blood vessels)
Where are neuroblasts and glioblasts generates?
ventricular zone
Function of radial glial cells?
“guide wires” for neuron migration
Alar plate –>
Basal plate –>
sensory neurons, and nuclei of spinal cord + brainstem
motor neurons and nuclei of spinal cord
Spinal column grows (faster/slower) than the spinal cord
faster
In the 3 month fetus, the conus medullaris terminates…
end of the spinal column
In the 9 month fetus, the spinal cord terminates…
at L3
In adults, the spinal cord terminates…
at L1/L2
What initiates neural plate formation?
notochord
Primary vesicles?
prosencephalon, mesencephalon, rhombencephalon
Failure of ant neural pole closure results in:
anencephaly
encephalocele
Failure of post neural pole closure results in:
spinda bifida
meningocele
myelomeningocele
Dx test for neural tube defects?
alpha fetal protein
SB occulta involves failure of..
mesodermal cells to form the bony dorsal vertebrae surrounding spinal cord
(neuro nml–no spinal cord involvement; tuft of hair)
