Embryology

Question 1

3 vesicles = __ weeks

5 vesicles = __ weeks

Answer 1

4

5

Question 2

Week #?

Neural plate is formed

Answer 2

3

Question 3

Week #?

Closure of pores

Answer 3

4

Question 4

Form all CNS neurons

Answer 4

neuroblasts

Question 5

Glioblasts form:

Answer 5

radial glial cells, astrocytes, oligodendrites, ependymocytes, choroid plexus

Question 6

When are radial glial cells formed?

Answer 6

before neuroblasts differentiate into neurons

Question 7

Microglia arise from…

Answer 7

monocytes in the circulation (invade CNS –> cerebral blood vessels)

Question 8

Where are neuroblasts and glioblasts generates?

Answer 8

ventricular zone

Question 9

Function of radial glial cells?

Answer 9

“guide wires” for neuron migration

Question 10

Alar plate –>

Basal plate –>

Answer 10

sensory neurons, and nuclei of spinal cord + brainstem

motor neurons and nuclei of spinal cord

Question 11

Spinal column grows (faster/slower) than the spinal cord

Answer 11

faster

Question 12

In the 3 month fetus, the conus medullaris terminates…

Answer 12

end of the spinal column

Question 13

In the 9 month fetus, the spinal cord terminates…

Answer 13

at L3

Question 14

In adults, the spinal cord terminates…

Answer 14

at L1/L2

Question 15

What initiates neural plate formation?

Answer 15

notochord

Question 16

Primary vesicles?

Answer 16

prosencephalon, mesencephalon, rhombencephalon

Question 17

Failure of ant neural pole closure results in:

Answer 17

anencephaly

encephalocele

Question 18

Failure of post neural pole closure results in:

Answer 18

spinda bifida
meningocele
myelomeningocele

Question 19

Dx test for neural tube defects?

Answer 19

alpha fetal protein

Question 20

SB occulta involves failure of..

Answer 20

mesodermal cells to form the bony dorsal vertebrae surrounding spinal cord
(neuro nml–no spinal cord involvement; tuft of hair)