Persons Flashcards

1
Q

Practical experience and theory in pcol

A

Claudius galen

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2
Q

Rational use of drugs

A

Claudius galen

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3
Q

Active ingredients in prescribed medicine

A

Theophrastus von hohenheim

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4
Q

Poisoner

A

Theophrastus von hohenheim

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5
Q

All subs are poison except for the right dose

A

Theophrastus von hohenheim

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6
Q

Animal experiments about pcol and toxi

A

Johann jakob wepfer

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7
Q

First institution of pharmacology

A

Rudolf buchheim, at univ of dorpat (estonia)

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8
Q

Chemical properties of drugs

A

Rudolf buchheim

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9
Q

Father of modern pcol

A

Oswald schmiedeberg

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10
Q

1st journal pcol

A

Archiv for experimental pathology and pharmacology

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11
Q

1st journal pcol who

A

Oswald schmiedeberg, bernhard naunyn, edwin klebs

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12
Q

SAR

A

Thomas richard frazer

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13
Q

Drug receptor

A

J. Langley

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14
Q

Selective toxicity

A

Paul ehrlich

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15
Q

First formalized receptor theory

A

Alexander j. Clark

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16
Q

Apply law of mass action to drug-receptor interactions

A

Alexander j. Clark

17
Q

Father of modern american pharmacology

A

John j. Abel

18
Q

Founder of journal or pharmacology and experimental therapeutics

A

John j. Abel

19
Q

Theoretical background of pcol

A

Claudius galen

20
Q

theory: pcol effect depends on the percentage of receptors occupied, affinity

A

Hypothesis of clark

21
Q

Theory: occupational, effectivenes lasts as long as the receptor is occupied, affinity and intrinsic activity

A

Theory of ariëns and stephenson

22
Q

Theory: rate, effectivenes does not depend upon actual occupation of the recotor but upon obtaining the proper stimulus only

A

Hypothesis of paton

23
Q

Theory: drug molecule must fit into the receptor

A

Lock and key theory