Perry 1

Question 1

Fed state vs non-fed state

Answer 1

• Fed stae
  
  • glucose used preferentially after meals
  • fats are stored
  • protein generally used for structural/functiona purposes
• Non-fed state
  
  • body uses endogenous sources
  • maintain serum glucose while limiting protein loss
  • glycogen –> storage of glucose (depleted after 12 hours
  • Protein and fats (glycerol then produce glucose
• Starvation
  
  • metabolic changes –> alternate fuel (ketones from fatty acids);
  • decrease protein catablism to allow conservation of lean tissue

Question 2

Potential clinical effects of higher glycemic index dietary carbohydrates

Answer 2

• reduced satiety and more rapid return of hunger
• increased prevalence of obesity
• increased risk for type 2 DM (insulin resistance increases)
• increased risk of coronary heart disease
  
  • serum glucose and insulin increase
  • increases Triglycerides, decrease HDL

Question 3

High fructose Corn Syrup

Answer 3

• HFCS-55 is the most commonly used
• similar structure to sucrose/table sugar
• Fructose absorption facilitated by glucose and other monosacchardies
• excess fructose consumption can lead to gastric distress/diarrhea
• fructose may impact hormone levels, satiety and food consumption