Peroxisome Flashcards

1
Q

Where are peroxisomes abundant, and what is their crystallized structure?

A

Peroxisomes are abundant in the liver. They have a crystallized structure of catalase.

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2
Q

What is the significance of plasmalogen, and where is its first reaction catalyzed?

A

The first reaction of plasmalogen is catalyzed in the peroxisome. It is particularly important for neurons.

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3
Q

Provide the chemical equation involving RH2, O2, R, and H2O2 related to peroxisomes.

A

“RH2 + O2 → R + H2O2 2H2O ↔ H2 + 2H2O”

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4
Q

Where are glyoxysomes and what is their function?

A

Glyoxysomes are only found in plants, and they convert fatty acids to glucose.

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5
Q

Describe the peroxisomal targeting sequences (PTS) and their receptors.

A

80% of C-terminus ones are named PTS1, and PTS1 goes to the Pex5 receptor. Pex5 goes to the Pex14 receptor, then inside, the Pex5 receptor is recycled.

-20% of N-terminus ones are named PTS2, and PTS2 goes to the Pex7 receptor. Pex5 goes to the Pex14 receptor, then inside, the Pex7 receptor is recycled.

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6
Q

What do PTS and Pex stand for?

A

PTS stands for peroxisomal targeting sequence, and Pex stands for Peroxins.

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7
Q

Is the origin of peroxisomes clear, or is there a debate regarding their formation?

A

The origin of peroxisomes is debated. It is questioned whether peroxisomes are ER vesicles budded off from the ER due to signaling

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