Mitochondria Flashcards
What has more mitochondria - neurons or other cells?
Neurons have more mitochondria.
Where are proteins folded during Mithocondrial transport
Proteins are folded in mitochondria. With chaperones they are held unfolded outside
What is Hsp70?
Hsp70 is a heat shock protein.
What does Hsp70 use as an energy source?
Hsp70 uses ATP.
Where does TOM translocate?
TOM translocates the outer membrane.
Where is SAM located? And What is it?
SAM is a subunit of the assembly machinery. And it’s on Outer mitochondrial membrane
Where are TOM and SAM located?
TOM and SAM are in the outer mitochondrial membrane.
Where is Hsp70 located?
Hsp70 hangs from TIM.
What pulls proteins inside the membrane?
Membrane potentials pull proteins from negative to positive charge.
Describe the process if a protein is inserted into the outer mitochondrial membrane.
It enters TOM, then the inner membrane space, and is kept unfolded by chaperones. Via SAM, it is inserted into the outer membrane.
How is a protein inserted into the inner membrane?
It can occur either from TOM to TIM or after TIM. OXA can also insert proteins synthesized in mitochondria.
Where can proteins be found in addition to the membranes?
Proteins can be found in the intermembrane space.
What is used as energy when there is an inter-signal sequence?
ATP is used as energy.
What inserts membranes into the mitochondrial structure?
TIM, SAM, and OXA insert membranes.
Does TOM insert membranes?
No, TOM does not insert membranes.
