Peripheral neurologic disorders, palsies Flashcards

1
Q

what nerves have the ability to heal

A

PNS nerves

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2
Q

what is CRPS

A

complex regional pain syndrome
pain that is out of proportion or unprovoked within a region of the body
most commonly in distal limb

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3
Q

what is often associated with abnormal sensation, motor function, vasomotor or atrophy

A

CRPS

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4
Q

what are the types 1 CRPS

A

most common
patient has pain but no evidecne of peripheral nerve injury

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5
Q

what is type 2 CRPS

A

peripheral nerve injury that is evident

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6
Q

what is the presentation of CRPS

A

typically seen within 4-6 weeks s/p trauma
pain - burning/stinging pain
sensation changes
motor changes
trophic changes (increased hair growth, changes in nails, fibrosis of tissue)
will have patient with increased pain, erythema, swelling of affected area

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7
Q

what is neuropathy

A

nerve dysfunction that leads to numbness or weakness

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8
Q

what is polyneuropathy

A

affects multiple distal nerves - nerve dysfunction that leads to numbness or weakness

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9
Q

what is peripheral neuropathy

A

nerve dysfunction that leads to numbness or weakness but includes radiculopathies and/or mononeuropathies

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10
Q

what is compression neuropathy

A

compression on the nerve will cause changes in the microvascular function
will ultimately cause structural changes
most common at areas where nerve goes through tight area

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11
Q

what are the different types of radiculopathies

A

avulsion, stretch and rupture

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12
Q

what is B12 deficiency

A

present in neurologic symptoms in late findings
B12 helps to maintain the myelin sheath

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13
Q

what is the presentation with B12 deficiency

A

neuropathy
dementia
neuropsychiatric
optic nerve atrophy

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14
Q

what is Guillain-Barre syndome

A

post infectious autoimmune demyelinating disease
most common after respiratory or GI illness (4+weeks-ish)
progressive neurologic dysfunction

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15
Q

what is the progression of Guillian - Barre syndrome

A

tingling/weakness in the legs working its way up - may lead to paralysis of LE and can progress to respiratory compromise

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16
Q

what Cranial nerve has Oligodendrocytes cells

A

CN2 - optic
optic neuritis

17
Q

what breaks down the myelin in Guillain - Barre syndrome

A

macrophages

18
Q

how long does remyelination occur in guillain-barre syndrome

A

weeks to months -patient may have residual symptoms

19
Q

what is the key characteristic symptoms of Guillain-Barre syndrome

A

symmetrical muscular weakness usually begins in the legs and ascends.