Peripheral Nervous System Flashcards
What are the two divisions of the autonomic nervous system
Sympathetic and Parasympathetic
How many neurons make up an autonomic pathway, and what are they called
2, preganglionic and postganglionic
Where do the cell bodies of preganglionic neurons lie
the spinal cord
Where do pre and post ganglionic neurons synapse
Ganglion
What is a ganglion
cluster of cell bodies outside of the CNS
Where are the sympathetic chain ganglia
just outside of the spinal cord, the point between where the dorsal root and ventral roots come together and before where the dorsal and ventral rami split
What is the collateral ganglia
It’s when the preganglionic neuron passes the chain ganglia without synapsing and synapses later.
What hormone is released by the parasympathetic preganglionic neuron
Acetylcholine
What hormone is released by the parasympathetic postganglionic neuron
Acetylcholine
What hormone is released by the sympathetic preganglionic neuron
Acetylcholine
What hormone is released by the parasympathetic postganglionic neuron
Norepinephrine
Epinephrine
What is a cholinergic receptor
receptors for ACH
What are the two types of cholinergic receptors
Nicotinic and Muscarinic
What is a nicotinic receptor
receptors at the synapse between pre and postganglionic neurons, they open cation channels (Na & K)
What is a muscarinic receptor
receptors between parasympathetic postganglionic neurons, they initiate cell signaling cascades
What is an adrenergic receptor
Receptor for norepinephrine and epinephrine
What are the two types of adrenergic receptors
alpha and beta
what are the subtypes of alpha and beta adrenergic receptors
alpha 1 and alpha 2
Beta 1 and Beta 2
nicotinic receptor steps
- ACH binds to receptor
- Na and K channel opens
- Na diffuses into the cell
Muscarinic receptor steps (heart)
- ACH binds to receptor
- G-protein subunits break off
- G-protein binds to K channel, opening it
- K diffuses out of the cell
What is the phrase for the sympathetic nervous system
Fight or flight
What is the phrase for the parasympathetic nervous system
Rest and digest
What is the effect of the sympathetic nervous system on the heart
Increases heart rate
increases conduction velocity
increases force of contraction
What is the effect of the parasympathetic nervous system on the heart
decrease heart rate
decreases conduction velocity
decreases force on contraction