Peripheral Nerve Blocks Flashcards
What class of drug includes bupivacaine, lidocaine, mepivacaine, prilocaine, and ropivacaine?
Amides
What is the maximum dose and duration for bupivacaine?
Max dose = 3 mg/kg
duration = 1.5 to 8 hours
What is the maximum dose and duration for lidocaine?
Max dose = 4.5 mg/kg (7 w epi)
duration = 0.75 to 2 hours
What is the maximum dose and duration for mepivacaine?
Max dose = 4.5 mg/kg ( 7 w epi)
duration = 1 to 2 hours
What is the maximum dose and duration for ropivacaine?
Max dose = 3 mg/kg
duration = 1.5 to 8 hours
What drug can be added to lidocaine in mepivacaine to prolong their action?
Epinephrine
Benzocaine, chloroprocaine, cocaine, procaine, and tetracaine all fall into what category of drugs?
Esters
It is more common to have an allergic reaction to amides or esters? why?
Esters
PABA
A toxic dose of benzocaine can cause what?
Met hemoglobinemia
How is met hemoglobinemia treated?
Methyline blue
Why is epinephrine added to local anesthetics?
Intravascular marker
improves quality of block
decreases absorption (prolong action)
vasoconstriction on surgical field
What are the three major risks of nerve blocks?
Systemic toxicity
infection
peripheral nerve damage
What is LAST?
Local anesthetic systemic toxicity
Which CNS symptoms come first C&S excitation or CNS depression?
CNS excitation
What are the cardiovascular effects of LAST?
Depression of myocardial conduction and contractility
production of arterial vasodilatation
How can LAST be prevented?
Incremental injection Frequent aspiration Adding a marker Limiting local anesthetic dose and concentration Communication with the patient