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N4 > Peripheral Auditory > Flashcards

Peripheral Auditory Flashcards

1
Q

Low-frequency cochlea has broad tuning with non-linear amplification

A

Recio-Spinoso and Oghalai, 2018

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2
Q

Cochlear amplification/tuning depend on Organ of Corti arrangement

A

Soons et al, 2018

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3
Q

Vibration hotspots reveal lungitudinal funnelling of sound-evokes motion in mammalian cochlea

A

Cooper et al, 2018

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4
Q

Mammalian behaviour and physiology converge to confirm sharper cochlea tuning in humans

A

Sumner et al, 2018

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5
Q

Muscarinic agonists and ATP increase intracellular Ca2+ concentration in chick cochlear hair cells, mediating efferent innervation

A

Shigemoto and Ohmori, 1990

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6
Q

Calcium capacitor shapes cholinergic inhibition of cochlear hair cells

A

Fuchs, 2014

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7
Q

Cytoskeleton/ECM may focus force on MET channel

A

Fettiplace et al, 2014

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8
Q

Heterogeneity of MET channel across taxa = difficult to isolate via homology

A

Fettiplace et al, 2014

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9
Q

Current step elicits dampened oscillation in membrane potential superimposed on step

A

Crawford and Fettiplace, 1981

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10
Q

Force generatiob by mammalian hair bundles supports role in cochlear amplification

A

Kennedy et al, 2005

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11
Q

Active hair bundle motion (towards kinocilium, then recoil) linked to fast transducer adaptation

A

Ricci et al, 2000

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12
Q

Hair bundle stiffness declines to steady-state, with time course comparable to adaptation

A

Howard and Hudspeth, 1987

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13
Q

Difference in IHC/OHC properties accounted for by combination of MET channels and tip link number

A

Beurg et al, 2006

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14
Q

TRPV4 knockouts show no auditory defects

A

Liedtke and Friedman, 2003

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15
Q

Characteristic frequency changes with position; conductance positively correlated with CF

A

Ricci et al, 2003

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16
Q

Transduction without tip links in cochlear hair cells mediated by ion channels with permeation properties distinct from those of MET channel

A

Marcotti et al, 2014

17
Q

Lipid bilayer mediates ion channel cooperativity in model of hair-cell mechanotransduction

A

Gianoli et al, 2017

18
Q

Ca2+ dependent adaptation of current with bundle displacement

A

Crawford et al, 1989

19
Q

Graded depolarisation with membrane resistance decrease and APs

A

Hudspeth and Corey, 1977

20
Q

Hair bundle drives fibre via active force-generating mechanism

A

Crawford and Fettiplace, 1985

N4 (7 decks)

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