Perinatal adaptions Flashcards
What is the function of the placenta?
Fetal homeostasis Gas change Nutrient and IgG transports Waste product removal Maintains acid base balance Produces hormones
What three shunts can be found within foetal circulation?
Foramen ovale
Ductus arteriosus
Ductus Venosus
What is the function of the foramen oval?
Allows oxygenated blood from the IVC to pass through the right atria into the lef.
What is the ductus arteriosus?
A shunt allowing blood from the pulmonary arteries to pass into the arch of the aorta
What is the ductus venosus?
A direct shunt between the umbilical vein and the IVC
What happens to the ductus venosus?
Becomes the ligamentum terres when it closes
What happens to the ductus arteriosus?
Closes and becomes the ligamentum arteriosus
What happens to the foramen ovale and why does this happen?
Closes as systemic pressure becomes higher than pulmonary.
What circulatory changes occur when the first breath occurs?
Pulmonary vascular resistance drops while systemic rises
Oxygen tension increases and PDE4 levels drop
What is PDE4 ?
The prostaglandin responsible for maintaining a patent ductus arteriosus
What can be administered to close the ductus arteriosus?
Indomethican or ibuprofen (NSAIDS)
What does the foetus do to prepare for birth?
Synthesis of surfactant and reduce the production of lung fluid.
Production of brown and subcutaneous fat
Swallos amniotic fluid
Where is brown fat located?
In between the scapulae and surrounding internal organs
What during labour occurs to the baby?
Increased maternal and foetal catelchoamines and cortisol
Vaginal delivery squeezes the lungs
What is PPHN?
Persistant Pulmonary Hypertension of the Newborn