Pericardial Disease + Myocarditis Flashcards
What is myocarditis
Inflammation of the myocardium
Acute or chronic
Causes reduced function and conduction
Often associated with pericarditis
What causes myocarditis
Idiopathic = 50% Viral Bacterial Fungal Parasitic Toxins Hypersensitivity Autoimmune
What are viral causes
Adenovirus Enterovirus Coxsackie CMV Influenza EBV HSV Hepatitis Mumps Rubella HIV
What are bacterial causes
Staph and strep Chlamydia Mycoplasma pneumoniae TB Meninigococcus Treponema pallidum (syphillis) Brucellosis Psittacosis
What are fungal causes
Aspergillus
Candida
What are parasitic causes
Schistosomiasis
Toxoplasmosis
Lyme’s
Leptospirosis
What toxins can cause
Alcohol
Lithium
Cocaine
What other drugs can cause
Cephalosporin TCA Penicillin Sulphonamide Cyclophosphamide Spirnolactone Carbamazepine Clozapine
What autoimmune can cause
SLE Sarcoid Churg-Strauss Sjogren Microscopic Macroscopic Kawasai
How does myocarditis present
ACS HF Arrythmia Palpitation Fatgiue Chest pain -pleuritic SOB Fever Tachycardia
How do you Dx myocarditis
ECG Cardiac biomarkers consistent with MI ECHO = diastolic dysfunction / effusion Bloods - raised ESR / CRP MRI if stable Biopsy = diagnostic Serology for cause
What does ECG show
Persistent ST elevation >3 hours - would evolve if ischaemia
T wave inversion
AV block
Prolonged QT
How do you treat myocarditis
Treat cause
Support HF
What are the complications of myocarditis
Impaired function
Impaired conduction
Arrythmia
DCM
What is pericarditis
Inflammation of pericardium (lining of heart) with or without myocardial involvement
What causes pericarditis
POST MI MYOCARDIAL RUPTURE Post viral - cocksackie Aortic dissection Same causes as myocarditis Cancer Hypothyroid