Perfusion Part One Flashcards
Very Nice Drugs
Verapamil,Nifedipine, Diltiazem
-pril
ACE inhibitors
-sartan
Angiotensin II. Receptor Blockers
-OLOL
Beta Blockers
RAAS
Renin Angiotensin Aldosterone System
1. Receptors recognize pressure change in vessels which stimulates kidneys to release renin into the bloodstream ( whenever BP is low)
2. Liver makes angiotensinogen which reacts with renin
3. This forms angiotensin I
4.Angiotensin 1 to Angiotensin II occurs in the lungs
5. Angiotensin II makes blood vessels small in diameter increasing BP (vasoconstrictor)
6. Angiotensin II to Angiotensin III releasing aldosterone
7. Aldosterone - BV increases and BP increases
Once optimal BP is reaches the kidneys will stop producing renin
Primary HTN
cause is unknown 90%
Secondary HTN
Cause/reason is known
10%
ANtihypertensive Drug Classifications
Ace inhibitors, ARBs, Beta Blockers, Ca Channel Blockers, Diuretics, Vasodilators
Antihypertensive Assess
Risk Factors (non modifiable and modifiable)
Check for High BP on multiple measurements
How many readings do you need to verify hypertension?
2
Antihypertensives Implement/Teach
Lifestyle change, take as prescribed, do not stop abruptly, proper BP taking technique, reduce coffee, ETOH, OTC meds
Antihypertensive Evaluate
BP WNL
Ace Inhibitors Use
HTN, heart failure
Ace Inhibitor Action
Prevents the conversion angiotensin I to II which prevents the release of aldosterone
Ace Inhibitor Adverse Effects
dry, nonproductive cough, which reverses when therapy is stopped, impotence, angioedema, Possible hyperkalemia~ K (> 5 meq/L) Mg, cardiac rhythm changes, cramping, diarrhea
What foods should you avoid when taking ace inhibitors?
Avoid high potassium items like bananas, zucchini, dried fruit, potatoes, spinach and salt substitutes
Arbs
Well tolerated, newer class
Do not cause a dry cough
Arbs Action
Allow angiotensin I to be converted to angiotensin II, but block the receptors that receive angiotensin II
Blocks vasoconstriction and release of aldosterone which lowers BP
ARBs drug examples
Losartan valsartan
Beta Blocker Use
HTN
Beta Blocker Action
Prevent/block beta receptors to accept epinephrine/nor- epinephrine
Beta Blocker Assess
• HTN,
•S/s of asthma, decreased HR, check for postural hypotension