Peptides Flashcards
Carnitine structure
Tri-methyl lysine
Carnitine function
Transport of FAs into mitochondria
What does carnitine require?
- SAMe
- Vitamin C
- Fe
- NAD+
- B6
Where is carnitine made?
- Liver
- Kidney
Where is carnitine stored?
Muscle
Creatine structure
Arginine + Glycine
Creatine function
Source of energy as creatine phosphate
Enzyme: Creatine kinase
Where is creatine made?
- Liver
- Kidney
Where is creatine stored?
Muscle (require SAMe)
Glutathione structure
Glu-Cys-Gly
Glutathione function
Antioxidant in RBCs and liver
What does glutathione require?
- Glutathione peroxidase (Se)
- Glutathione reductase (NADPH and FADH2)
Endorphins structure
Peptide
Endorphin function
- Receptors in brain, gut and WBCs
- Runners high, joy
Bradykin structure
Peptide
Bradykin function
Smooth muscle hypotensive agent released in response to tissue damage
What does bradykin begin?
Arachidonic cascade (pain and inflammation pathway)
Insulin structure
Peptide with disulfide bond
Insulin function
What: Binds to the Glut 4 receptor
Where: in muscle and adipose tissue
Why: to allow glucose to enter the cell
What is insulin not needed for?
- Glut 1: RBC and brain
- Glut 2: Liver
What peptides require SAMe?
- Carnitine
- Creatine
