Peptides Flashcards

1
Q

Carnitine structure

A

Tri-methyl lysine

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2
Q

Carnitine function

A

Transport of FAs into mitochondria

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3
Q

What does carnitine require?

A
  • SAMe
  • Vitamin C
  • Fe
  • NAD+
  • B6
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4
Q

Where is carnitine made?

A
  • Liver
  • Kidney
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5
Q

Where is carnitine stored?

A

Muscle

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6
Q

Creatine structure

A

Arginine + Glycine

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7
Q

Creatine function

A

Source of energy as creatine phosphate
Enzyme: Creatine kinase

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8
Q

Where is creatine made?

A
  • Liver
  • Kidney
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9
Q

Where is creatine stored?

A

Muscle (require SAMe)

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10
Q

Glutathione structure

A

Glu-Cys-Gly

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11
Q

Glutathione function

A

Antioxidant in RBCs and liver

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12
Q

What does glutathione require?

A
  • Glutathione peroxidase (Se)
  • Glutathione reductase (NADPH and FADH2)
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13
Q

Endorphins structure

A

Peptide

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14
Q

Endorphin function

A
  • Receptors in brain, gut and WBCs
  • Runners high, joy
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15
Q

Bradykin structure

A

Peptide

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16
Q

Bradykin function

A

Smooth muscle hypotensive agent released in response to tissue damage

17
Q

What does bradykin begin?

A

Arachidonic cascade (pain and inflammation pathway)

18
Q

Insulin structure

A

Peptide with disulfide bond

19
Q

Insulin function

A

What: Binds to the Glut 4 receptor
Where: in muscle and adipose tissue
Why: to allow glucose to enter the cell

20
Q

What is insulin not needed for?

A
  • Glut 1: RBC and brain
  • Glut 2: Liver
21
Q

What peptides require SAMe?

A
  • Carnitine
  • Creatine