Peptic Ulcer Disease/Gastitis/GERD

Question 1

What suffix is used when there is a discontinuation from the mucosa to the submucosa in the GIT

Answer 1

Itis

Example: gastritis

Question 2

What suffix is used when there is a discontinuation from the mucosa to the muscular layer in the GIT

Answer 2

Erosion

Question 3

What suffix is used when there is a discontinuation from the mucosa to the serosa in the GIT

Answer 3

Ulcer

Question 4

Where are the parietal cells found

Answer 4

In the midsection of the oxyntic glands

Question 5

What are some defensive factors of the GIT

Answer 5

Mucus production
Bicarbonate production
Mucosal blood flow (more important in the development of stress cancer)
High epithelial cell turnover
PGE2 (produces bicarbonate and mucus, blood flow)

Question 6

What are some aggressive factors of the GIT

Answer 6

H. pylori
Acid secretion
Pepsinogen secretion
NSAIDs
Cigarette smoking
Corticosteroid use

Question 7

At which pH is pepsinogen converted to pepsin

Answer 7

pH<3.5

Question 8

What are some sites of ulcer preparation

Answer 8

First portion of the duodenum
Stomach
Margins of a gasterectomy
In the duodenum, jejenum and ileum with patients with Zollinger-Ellinson syndrome