pepsin Flashcards

1
Q

______ is a proteolytic enzyme that can contribute to ulcer formation

A

pepsin

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2
Q

pepsin forms ulcers by breaking down protein in the ______ wall

A

gut wall

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3
Q

activity of pepsin is _____ dependent

A

PH dependent

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4
Q

what are the types of drugs that elevate gastric PH

A

antacids; histamine 2; antagonists; PPIs

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5
Q

drugs that elevate gastric PH for example antacids; histamine 2; antagonists; PPIs can cause ____ to increase thereby enhancing pepsin’s destructive effects

A

peptic activity to increase

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6
Q

to avoid activation of pepsin, drugs that reduce acidity should be administered in doses sufficient to raise the gastric ph above ______

A

5

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