histamine 2 receptor antagonists/ cimetidine (tagamet) Flashcards
the drugs listed are called ____
Cimetidine [Tagamet]
Ranitidine [Zantac]
Famotidine [Pepcid]
Nizatidine [Axid
histamine 2 receptor antagonists
when taking cimetidine (tagamet); the theophylline dose needs to be _____while taking this medication
reduced
_______ are the first choice drugs for treating gastric and duodenal ulcers
histamine 2 receptor antagonists
histamine 2 receptors promote healing by suppressing secretion of _________
suppresses gastric acid
all four are equally ____
effective
serious side effects are _______
uncommon
H2Rantagonist cimetidine (tagamet) is absorbed slowly if taken with ________
meals
cimetidine (tagamet) cross the ____ ____ barrier with difficultly
blood brain barrier
cimetidine (tagamet) may cause _____ symptoms such as dizziness; drowsiness; headache
CNS symptoms
what are the therapeutic uses that H2R antagonist cimetidine (tagamet) used for
gastric and duodenal ulcers
GERD
Zollinger- Ellison syndrome
aspiration pneumonitis
heartburn; acid indigestion; sour stomach
adverse effects of cimetidine (tagamet)
antiandrogenic effects
CNS effects
pneumonia
IV bolus
adverse effects of cimetidine (tagamet) IV bolus can cause
hypotension and dysrhythmias
drug interactions of cimetidine (tagamet)
warfarin; theophylline; lidocaine; antacids
taking cimetidine (tagamet) with antacids can reduce absorption of ________
cimetidine (tagamet)
cimetidine and antacids should be administered at least _____ hour apart
1 hr apart