other antiulcer drugs Flashcards

1
Q

other antiulcer drugs include

A

Sucralfate [Carafate]
Misoprostol [Cytotec]
Antacids

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2
Q

what is the main thing that sucralfate ( Carafate) do

A

coats stomach lining

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3
Q

you want to administer sucralfate (carafate) without

A

without food or fluids

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4
Q

sucralfate creates a protective barrier for up to ___ hrs

A

up to 6hrs

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5
Q

therapeutic use of sucralfate (carafate) is that it treats ______ ulcers and and is used as a _______ therapy

A

treats acute ulcers; and is a maintenance therapy

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6
Q

adverse effect of sucralfate (carafate ) is ____ which happens to only 2% of patients

A

constipation

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7
Q

drugs interactions with sucralfate (carafate) are ___

A

minimal

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8
Q

____ may interfere with the effects of sucralfate (carafate)

A

antacids may interfere with its effects

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9
Q

sucralfate is common in what settings

A

hospital

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10
Q

why do you want to take sucralfate without foods and fluids

A

because it has to protect the stomach lining

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11
Q

Misoprostol (cytotec) only approved GI indication is to prevent gastric ulcers caused by long term _____

A

long term NSAIDs therapy

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12
Q

the most common adverse effects of misoprostol (cytotec) are

A

dose- related diarrhea; abdominal pain

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13
Q

misoprostol ( cytotec) is contraindicated during ___ which is category X

A

contraindicated during pregnancy

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14
Q

significant actions need to be taken to ensure that ____ does not occur after therapy starts and that the patient is not _____ during therapy initiation

A

pregnancy; pregnant

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15
Q

antacids react with gastric acids to produce ____ or ____ salts

A

produce neutral salts or salts with low acidity

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16
Q

antacids reduces destruction of ___ by neutralizing acid

A

reduces destruction of gut wall

17
Q

antacids may also enhance mucosal protection by stimulating production of _____

A

prostaglandins

18
Q

except for ____; antacids do not alter system PH

A

sodium bicarbonate

19
Q

use antacids with precaution with patients who have ___ impairment

A

renal impairment

20
Q

the 3 adverse effects of antacids are

A

constipation; diarrhea; and sodium loading

21
Q

what antacid causes constipation

A

aluminum hydroxide

22
Q

what antacid causes diarrhea

A

magnesium hydroxide

23
Q

drug interactions of antacids include ___;___; and ___

A

cimetidine; ranitidine; sucralfate