Pentose Phosphate Pathway Flashcards
What is ribose-5-P a precursor for? (5)
DNA & RNA synthesis, ATP, NADH, FADH2, CoASH
What is NADPH a precursor for? (3)
Fatty acid synthesis, cholesterol and steroid hormones and protection from antioxidants.
What are the two phases of the PPP
Oxidative and non-oxidative phase
What happens in the oxidative phase of the PPP?
Ribose-5-P and NADPH are formed
What happens in the non-oxidative phase of the PPP?
Recycling of pentose sugars into hexose sugars.
What are the key metabolic products of the pentose phosphate pathway?
Ribose-5-P and NADPH
What general role does NADPH play in metabolism compared to NADH?
NADH is mainly involved in catabolism whereas NADPH is in anabolic processes and detoxification.