Pentose Phosphate Pathway

Question 1

Where does the pentose pathway occur in the cell? What type of cells?

Answer 1

In the cytosol. In liver cells.

Question 2

The oxidative branch of the PPP is also called?

Answer 2

The hexose monophospate shunt

Question 3

Where does the Oxidative branch of PPP occur in the glycolysis pathway? What enzyme is used and what is mainly produced? Reversible?

Answer 3

At Glucose 6-P. Glucose 6-P Dehydrogenase. Produces 2 NADPH, 1 CO2 and 3 Ribose-5P. Irreversible.

Question 4

What is Glucose 6-P Dehydrogenase inhibited by?

Answer 4

NADPH

Question 5

What is NADPH also involved in? Helps regenerate what?

Answer 5

it is used in the reduction of reactive oxygen species. Used to regenerate Glutathione.

Question 6

What is the most common human deficient enzyme?

Answer 6

G6PDH

Question 7

Where does the non-oxidative branch of PPP start on the Glycolysis pathway? What does it produce? Reversible?

Answer 7

The Fructose 6-P, and splitting phase of GA-3P. Produces 3 Ribose-5P. Reversible.