Pentose Phosphate Pathway

Question 1

Net ATP?

Answer 1

No ATP used or gained

Question 2

Oxidative phase

Answer 2

Irreversible
Generates NADPH
Glucose 6 phosphate to 
6 phosphogluconate to 
Ribulose then ribose

Question 3

Enzyme in oxidative phase

Answer 3

Glutathione reductase
Glucose 6 phosphate to
6 phosphogluconate

Question 4

Nonoxidative phase

Answer 4

Reversible
Can inter convert sugars to make more ribose

Ribulose 5 phosphate to
Ribose 5 phosphate
Or back to glucose 6 phosphate to
Make more NADPH

Question 5

Enzyme in Nonoxidative

Answer 5

Transketolase

Or transaldolase

Question 6

NADPH

Answer 6

Donator
Antioxidant, protects against super oxides in RBC
Ex fava bean disease

Question 7

Nonoxidative phase

Answer 7

When ribose is not needed but NADPH is

Ribose to Ribulose to xylose to G6P

Question 8

Transketolase

Answer 8

Converts xylose to glyceraldehyde and more

Occurs twice

Question 9

The oxidation of 3 glucose in pentose phosphate pathway may yield

Answer 9

3 CO2
6 NADPH
3 pentose

Question 10

What is it

Answer 10

It’s a metabolic pathway that occurs aside glycolysis, glucose 6 phosphate is shunted from glycolysis and enters the pentose phosphate pathway