Penicillins Flashcards

1
Q

Groups of penicillins

A

Narrow-spectrum
Penicillinase-resistant
Extended spectrum

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2
Q

Groups of extended spectrum penicillins + their drugs (4 drugs)

A

Aminopenicillins - amoxicillin + ampicillin

Antipsuedomonal penicillins - piperacillin + ticarcillin)

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3
Q

Narrow-spectrum penicillins (2 drugs)

A

Penicillin V

Penicillin G

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4
Q

Penicillinase-resistant penicillins (2 drugs)

A

Dicloxacillin

Nafcillin

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5
Q

Acid-stable penicillins (3 drugs)

A

Amoxicillin
Dicloxacillin
Penicillin V

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6
Q

Acid-liable penicillins (2 drugs)

A

Ticarcillin

Piperacillin

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7
Q

Which penicillins can only be adm parenterally?

A

Ticarcillin

Piperacillin

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8
Q

Do penicillins cross BBB?

A

Only when inflamed

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9
Q

Long-acting forms of penicillin G + adm

A

Adm IM
Procaine penicillin G
Benzathine penicillin G

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10
Q

Narrow-spectrum penicillins - indications

A

Streptococcal inf

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11
Q

Penicillin G - indicaions

A

Syphilis, endocarditis, meningitis, pneumonia, gas gangrene

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12
Q

Penicillin V - indications

A

Pharyngitis

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13
Q

Penicillinase-restistant penicillins - indications

A

Osteomyelitis, endocarditis, pneumonia, skin & soft tissue infections

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14
Q

Amoxicillin is often combined with (drug + group of drug)

A

Clavulanate

Beta-lactamase inhibitor

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15
Q

Ampicillin is often combined with (drug + group of drug)

A

Sulbactam

Beta-lactamase inhibitor

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16
Q

Amoxicillin - indications

A
Otitis media, sinusitis, bronchitis, pneumonia, UTIs.
Bite wounds (combo with clavulanate)
17
Q

Ampicillin - indications

A

Meningitis, decubitus, diabetic foot ulcers, endocarditis, lyme disease

18
Q

Piperacillin is often combined with (drug + group of drugs)

A

Tazobactam

Beta-lactamase inhibitor

19
Q

Antipsuedomonal penicillins - indications

A

Intra-abdominal, skin, soft tissue inf.
Pneumonia
Complicated UTIs

20
Q

Penicillins - adverse effects

A

Hypersensitivity (urticaria, anaphylaxis, serum sickness, hepatitis)
Seizures (high doses), superinfections, psuedomembranous colitis

21
Q

Ampicillin - adverse effects

A

Maculopapular rash