Monobactam & Carbapenems Flashcards
Monobactam (1 drug)
Aztreonam
Aztreonam - indications
UTI, gynecologic, intra-abdominal, skin, lung infections.
Especially for multidrug-resistant strains
Aztreonam - adverse effects
Hypersensitivity, thrombophlebitis
Can aztreonam be used in people with allergy to other betalactams?
Yes
Carbapenems (4 drugs)
Imipenem
Meropenem
Ertapenem
Doripenem
Ultra-broad-spectrum carbapenem
Doripenem
Carbapenems - indications
Endocaridits, pneumonia, UTI, pelvic, skin, soft tissue, intra-abdominal infections
Can carbapenems be used in people with allergy to other betalactams?
No
Carbapenems - adverse effects
Anemia, leukopenia, thrombocytopenia, altered bleeding time.
Seizures (epilepsy), cross-sensitivity